Reactome | Ligand-responsive EGFR mutants sensitive to non-covalent TKIs [plasma membrane]

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Ligand-responsive EGFR mutants sensitive to non-covalent TKIs [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-1220583] Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] - Homo sapiens [Complex:R-HSA-1220580] EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] - Homo sapiens
created	[InstanceEdit:1176055] Orlic-Milacic, Marija, 2011-01-24
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	1176052
disease	[Disease:1500689] cancer
displayName	Ligand-responsive EGFR mutants sensitive to non-covalent TKIs [plasma membrane]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-1177542] EGFR L861Q [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1177532] EGFR G719A [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1177531] EGFR G719C [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1228025] EGFR E746_S752delinsV [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1228031] EGFR E746_T751delinsA [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1228034] EGFR L747_A750delinsP [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1228016] EGFR L747_S752del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1228015] EGFR L747_T751del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1228012] EGFR L747_T751delinsP [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1996327] EGFR A289D [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1996306] EGFR A289T [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1996321] EGFR A289V [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1996314] EGFR G598V [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1996330] EGFR R108K [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1996315] EGFR T263P [plasma membrane] - Homo sapiens
hasMember	[EntityWithAccessionedSequence:R-HSA-1173212] EGFR L858R [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1169418] EGFR G719S [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1181211] EGFR E746_A750del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1228010] EGFR L747_P753delinsS [plasma membrane] - Homo sapiens
inDisease	true
maxDepth	2
memberOf	[DefinedSet:R-HSA-1182966] Ligand-responsive EGFR mutants [plasma membrane] - Homo sapiens
modified	[InstanceEdit:2053973] Orlic-Milacic, Marija, 2012-01-12
name	Ligand-responsive EGFR mutants sensitive to non-covalent TKIs
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-1176052

Referrals

(hasComponent)	[Complex:R-HSA-1220580] EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] [Complex:R-HSA-1220583] Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]
(hasMember)	[DefinedSet:R-HSA-1182966] Ligand-responsive EGFR mutants [plasma membrane]

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