Reactome | EGFR A289T [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-1176052] Ligand-responsive EGFR mutants sensitive to non-covalent TKIs [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1996320] Orlic-Milacic, Marija, 2011-11-19
crossReference	[DatabaseIdentifier:12021378] Mondo:0002544 [DatabaseIdentifier:1996297] COSMIC:COSV51770322
dbId	1996306
disease	[Disease:1500689] cancer [Disease:1247632] glioblastoma [Disease:1996312] brain glioma [Disease:1996318] astrocytoma [Disease:1996329] brain oligodendroglioma
displayName	EGFR A289T [plasma membrane]
endCoordinate	1210
hasModifiedResidue	[ReplacedResidue:1996316] L-alanine 289 replaced with L-threonine
inDisease	true
maxDepth	1
modified	[InstanceEdit:3662293] Orlic-Milacic, M, 2013-06-06
name	EGFR A289T Epidermal Growth Factor Receptor A289T EGFR Ala289Thr
referenceEntity	[ReferenceGeneProduct:uniprot:P00533] UniProt:P00533 EGFR
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-1996306
startCoordinate	25
updateTrackers	[UpdateTracker:9887775] Update Tracker - [EntityWithAccessionedSequence:1996306] EGFR A289T [plasma membrane] - v46:[modifyName]

(updatedInstance)	[UpdateTracker:9887775] Update Tracker - [EntityWithAccessionedSequence:1996306] EGFR A289T [plasma membrane] - v46:[modifyName]
(hasCandidate)	[CandidateSet:R-HSA-1176052] Ligand-responsive EGFR mutants sensitive to non-covalent TKIs [plasma membrane]

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