Reactome | 2OG [nucleoplasm]

Schema > SimpleEntity > Entries

2OG [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-GGA-353356] Reversal of Alkylation Damage By DNA Dioxygenases - Gallus gallus [Reaction:R-HSA-112124] Oxidative demethylation of 3-meC damaged DNA By ALKBH3 - Homo sapiens [Reaction:R-HSA-112120] Oxidative demethylation of 3-meC damaged DNA by ALKBH2 - Homo sapiens [Reaction:R-HSA-112118] Oxidative demethylation of 1-meA damaged DNA by ALKBH2 - Homo sapiens [Reaction:R-DDI-9630967] RIOX2Fe2+ hydroxylates a histidine residue of RPL27A - Dictyostelium discoideum [Reaction:R-GGA-9630967] RIOX2Fe2+ hydroxylates a histidine residue of RPL27A - Gallus gallus [Reaction:R-SSC-9630967] RIOX2Fe2+ hydroxylates a histidine residue of RPL27A - Sus scrofa [Reaction:R-BTA-9630967] RIOX2Fe2+ hydroxylates a histidine residue of RPL27A - Bos taurus [Reaction:R-CFA-9630967] RIOX2Fe2+ hydroxylates a histidine residue of RPL27A - Canis familiaris [Reaction:R-RNO-9630967] RIOX2Fe2+ hydroxylates a histidine residue of RPL27A - Rattus norvegicus [Reaction:R-MMU-9630967] RIOX2Fe2+ hydroxylates a histidine residue of RPL27A - Mus musculus [Reaction:R-HSA-9630967] RIOX2Fe2+ hydroxylates a histidine residue of RPL27A - Homo sapiens [Reaction:R-CEL-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Caenorhabditis elegans [Reaction:R-CEL-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Caenorhabditis elegans [Reaction:R-DME-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Drosophila melanogaster [Reaction:R-DME-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Drosophila melanogaster [Reaction:R-XTR-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Xenopus tropicalis [Reaction:R-XTR-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Xenopus tropicalis [Reaction:R-DRE-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Danio rerio [Reaction:R-DRE-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Danio rerio [Reaction:R-SSC-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Sus scrofa [Reaction:R-SSC-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Sus scrofa [Reaction:R-BTA-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Bos taurus [Reaction:R-BTA-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Bos taurus [Reaction:R-CFA-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Canis familiaris [Reaction:R-CFA-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Canis familiaris [Reaction:R-RNO-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Rattus norvegicus [Reaction:R-RNO-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Rattus norvegicus [Reaction:R-MMU-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Mus musculus [Reaction:R-MMU-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Mus musculus [Reaction:R-HSA-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Homo sapiens [Reaction:R-HSA-9630022] JMJD6 dimer hydroxylates lysine residues of U2AF2 - Homo sapiens [Reaction:R-DDI-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Dictyostelium discoideum [Reaction:R-CEL-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Caenorhabditis elegans [Reaction:R-DME-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Drosophila melanogaster [Reaction:R-GGA-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Gallus gallus [Reaction:R-XTR-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Xenopus tropicalis [Reaction:R-DRE-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Danio rerio [Reaction:R-SSC-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Sus scrofa [Reaction:R-BTA-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Bos taurus [Reaction:R-CFA-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Canis familiaris [Reaction:R-RNO-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Rattus norvegicus [Reaction:R-MMU-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Mus musculus [Reaction:R-HSA-9630993] RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 - Homo sapiens [Reaction:R-SCE-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Saccharomyces cerevisiae [Reaction:R-SPO-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Schizosaccharomyces pombe [Reaction:R-CEL-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Caenorhabditis elegans [Reaction:R-DME-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Drosophila melanogaster [Reaction:R-GGA-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Gallus gallus [Reaction:R-XTR-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Xenopus tropicalis [Reaction:R-DRE-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Danio rerio [Reaction:R-SSC-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Sus scrofa [Reaction:R-BTA-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Bos taurus [Reaction:R-CFA-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Canis familiaris [Reaction:R-RNO-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Rattus norvegicus [Reaction:R-MMU-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Mus musculus [Reaction:R-HSA-9630769] OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 - Homo sapiens [Reaction:R-MMU-9822448] Kdm5b demethylates histone H3 trimethyllysine-4 (H3K4me3) - Mus musculus [Reaction:R-MMU-9822448] Kdm5b demethylates histone H3 trimethyllysine-4 (H3K4me3) - Mus musculus [Reaction:R-MMU-9822448] Kdm5b demethylates histone H3 trimethyllysine-4 (H3K4me3) - Mus musculus [Reaction:R-HSA-9822461] KDM5B demethylates histone H3 trimethyllysine-4 (H3K4me3) - Homo sapiens [Reaction:R-HSA-9822461] KDM5B demethylates histone H3 trimethyllysine-4 (H3K4me3) - Homo sapiens [Reaction:R-HSA-9822461] KDM5B demethylates histone H3 trimethyllysine-4 (H3K4me3) - Homo sapiens [Reaction:R-HSA-9817458] TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 - Homo sapiens [Reaction:R-MMU-9822463] Kdm5a demethylates histone H3 trimethyllysine-4 (H3K4me3) - Mus musculus [Reaction:R-MMU-9822463] Kdm5a demethylates histone H3 trimethyllysine-4 (H3K4me3) - Mus musculus [Reaction:R-MMU-9822463] Kdm5a demethylates histone H3 trimethyllysine-4 (H3K4me3) - Mus musculus [Reaction:R-HSA-9822467] KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) - Homo sapiens [Reaction:R-HSA-9822467] KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) - Homo sapiens [Reaction:R-HSA-9822467] KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) - Homo sapiens [Reaction:R-MMU-1234165] Nuclear PHD1,3 hydroxylates proline residues on HIF3A - Mus musculus [Reaction:R-HSA-1234165] Nuclear PHD1,3 hydroxylates proline residues on HIF3A - Homo sapiens [Reaction:R-RNO-1234165] Nuclear PHD1,3 hydroxylates proline residues on HIF3A - Rattus norvegicus [Reaction:R-CFA-1234165] Nuclear PHD1,3 hydroxylates proline residues on HIF3A - Canis familiaris [Reaction:R-BTA-1234165] Nuclear PHD1,3 hydroxylates proline residues on HIF3A - Bos taurus [Reaction:R-SSC-1234165] Nuclear PHD1,3 hydroxylates proline residues on HIF3A - Sus scrofa [Reaction:R-DRE-1234165] Nuclear PHD1,3 hydroxylates proline residues on HIF3A - Danio rerio [Reaction:R-XTR-1234165] Nuclear PHD1,3 hydroxylates proline residues on HIF3A - Xenopus tropicalis [Reaction:R-GGA-1234165] Nuclear PHD1,3 hydroxylates proline residues on HIF3A - Gallus gallus [Reaction:R-DME-1234165] Nuclear PHD1,3 hydroxylates proline residues on HIF3A - Drosophila melanogaster [Reaction:R-CEL-1234165] Nuclear PHD1,3 hydroxylates proline residues on HIF3A - Caenorhabditis elegans [Reaction:R-MMU-5220936] Tet1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine - Mus musculus [Reaction:R-HSA-5220952] TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine - Homo sapiens [Reaction:R-MMU-5220931] Tet1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine - Mus musculus [Reaction:R-MMU-5220944] Tet1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine - Mus musculus [Reaction:R-HSA-5220990] TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine - Homo sapiens [Reaction:R-HSA-112125] Oxidative dealkylation of 1-EtA damaged DNA by ABH3 - Homo sapiens [Reaction:R-HSA-112123] Oxidative demethylation of 1-meA damaged DNA By ALKBH3 - Homo sapiens [Reaction:R-GGA-8857692] RNA demethylases demethylate N6-methyladenosine RNA - Gallus gallus [Reaction:R-XTR-8857692] RNA demethylases demethylate N6-methyladenosine RNA - Xenopus tropicalis [Reaction:R-DRE-8857692] RNA demethylases demethylate N6-methyladenosine RNA - Danio rerio [Reaction:R-SSC-8857692] RNA demethylases demethylate N6-methyladenosine RNA - Sus scrofa [Reaction:R-BTA-8857692] RNA demethylases demethylate N6-methyladenosine RNA - Bos taurus [Reaction:R-CFA-8857692] RNA demethylases demethylate N6-methyladenosine RNA - Canis familiaris [Reaction:R-RNO-8857692] RNA demethylases demethylate N6-methyladenosine RNA - Rattus norvegicus [Reaction:R-MMU-8857692] RNA demethylases demethylate N6-methyladenosine RNA - Mus musculus [Reaction:R-HSA-8857692] RNA demethylases demethylate N6-methyladenosine RNA - Homo sapiens [Reaction:R-HSA-112121] Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 - Homo sapiens [Reaction:R-MMU-9822964] Kdm6a (Utx) demethylates trimethylated histone H3 lysine-27 (H3K27me3) - Mus musculus [Reaction:R-MMU-9822964] Kdm6a (Utx) demethylates trimethylated histone H3 lysine-27 (H3K27me3) - Mus musculus [Reaction:R-HSA-9822985] KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) - Homo sapiens [Reaction:R-HSA-9822985] KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) - Homo sapiens [Reaction:R-MMU-9822924] Kdm6b (Jmjd3) demethylates histone H3 trimethyllysine-27 (H3K27me3) - Mus musculus [Reaction:R-MMU-9822924] Kdm6b (Jmjd3) demethylates histone H3 trimethyllysine-27 (H3K27me3) - Mus musculus [Reaction:R-HSA-9822914] KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) - Homo sapiens [Reaction:R-HSA-9822914] KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) - Homo sapiens [Reaction:R-MMU-9817463] Tet3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 dimethylated on lysine-9 - Mus musculus [Reaction:R-SCE-5423117] PHF8 demethylates MeK21-histone H4 - Saccharomyces cerevisiae [Reaction:R-SPO-5423117] PHF8 demethylates MeK21-histone H4 - Schizosaccharomyces pombe [Reaction:R-CEL-5423117] PHF8 demethylates MeK21-histone H4 - Caenorhabditis elegans [Reaction:R-XTR-5423117] PHF8 demethylates MeK21-histone H4 - Xenopus tropicalis [Reaction:R-DRE-5423117] PHF8 demethylates MeK21-histone H4 - Danio rerio [Reaction:R-SSC-5423117] PHF8 demethylates MeK21-histone H4 - Sus scrofa [Reaction:R-BTA-5423117] PHF8 demethylates MeK21-histone H4 - Bos taurus [Reaction:R-CFA-5423117] PHF8 demethylates MeK21-histone H4 - Canis familiaris [Reaction:R-RNO-5423117] PHF8 demethylates MeK21-histone H4 - Rattus norvegicus [Reaction:R-MMU-5423117] PHF8 demethylates MeK21-histone H4 - Mus musculus [Reaction:R-HSA-5423117] PHF8 demethylates MeK21-histone H4 - Homo sapiens [Reaction:R-CEL-4724279] KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-4724279] KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 - Danio rerio [Reaction:R-SSC-4724279] KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 - Sus scrofa [Reaction:R-BTA-4724279] KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 - Bos taurus [Reaction:R-CFA-4724279] KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 - Canis familiaris [Reaction:R-RNO-4724279] KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 - Rattus norvegicus [Reaction:R-MMU-4724279] KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 - Mus musculus [Reaction:R-HSA-4724279] KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 - Homo sapiens [Reaction:R-CEL-4722133] KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-4722133] KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 - Danio rerio [Reaction:R-SSC-4722133] KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 - Sus scrofa [Reaction:R-BTA-4722133] KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 - Bos taurus [Reaction:R-CFA-4722133] KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 - Canis familiaris [Reaction:R-RNO-4722133] KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 - Rattus norvegicus [Reaction:R-MMU-4722133] KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 - Mus musculus [Reaction:R-HSA-4722133] KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 - Homo sapiens [Reaction:R-CEL-5661121] KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-5661121] KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 - Danio rerio [Reaction:R-SSC-5661121] KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 - Sus scrofa [Reaction:R-BTA-5661121] KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 - Bos taurus [Reaction:R-CFA-5661121] KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 - Canis familiaris [Reaction:R-RNO-5661121] KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 - Rattus norvegicus [Reaction:R-MMU-5661121] KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 - Mus musculus [Reaction:R-HSA-5661121] KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 - Homo sapiens [Reaction:R-CEL-5661120] KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-5661120] KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 - Danio rerio [Reaction:R-SSC-5661120] KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 - Sus scrofa [Reaction:R-BTA-5661120] KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 - Bos taurus [Reaction:R-CFA-5661120] KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 - Canis familiaris [Reaction:R-RNO-5661120] KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 - Rattus norvegicus [Reaction:R-MMU-5661120] KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 - Mus musculus [Reaction:R-HSA-5661120] KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 - Homo sapiens [Reaction:R-CEL-5661122] JMJD6 demethylates Me2R3-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-5661122] JMJD6 demethylates Me2R3-histone H3 - Danio rerio [Reaction:R-SSC-5661122] JMJD6 demethylates Me2R3-histone H3 - Sus scrofa [Reaction:R-BTA-5661122] JMJD6 demethylates Me2R3-histone H3 - Bos taurus [Reaction:R-CFA-5661122] JMJD6 demethylates Me2R3-histone H3 - Canis familiaris [Reaction:R-RNO-5661122] JMJD6 demethylates Me2R3-histone H3 - Rattus norvegicus [Reaction:R-MMU-5661122] JMJD6 demethylates Me2R3-histone H3 - Mus musculus [Reaction:R-HSA-5661122] JMJD6 demethylates Me2R3-histone H3 - Homo sapiens [Reaction:R-PFA-4724284] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 - Plasmodium falciparum [Reaction:R-CEL-4724284] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-4724284] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 - Danio rerio [Reaction:R-SSC-4724284] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 - Sus scrofa [Reaction:R-BTA-4724284] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 - Bos taurus [Reaction:R-CFA-4724284] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 - Canis familiaris [Reaction:R-RNO-4724284] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 - Rattus norvegicus [Reaction:R-MMU-4724284] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 - Mus musculus [Reaction:R-HSA-4724284] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 - Homo sapiens [Reaction:R-CEL-5661125] JMJD6 demethylates Me2sR4-HIST1H4 - Caenorhabditis elegans [Reaction:R-DME-5661125] JMJD6 demethylates Me2sR4-HIST1H4 - Drosophila melanogaster [Reaction:R-GGA-5661125] JMJD6 demethylates Me2sR4-HIST1H4 - Gallus gallus [Reaction:R-XTR-5661125] JMJD6 demethylates Me2sR4-HIST1H4 - Xenopus tropicalis [Reaction:R-DRE-5661125] JMJD6 demethylates Me2sR4-HIST1H4 - Danio rerio [Reaction:R-SSC-5661125] JMJD6 demethylates Me2sR4-HIST1H4 - Sus scrofa [Reaction:R-BTA-5661125] JMJD6 demethylates Me2sR4-HIST1H4 - Bos taurus [Reaction:R-CFA-5661125] JMJD6 demethylates Me2sR4-HIST1H4 - Canis familiaris [Reaction:R-RNO-5661125] JMJD6 demethylates Me2sR4-HIST1H4 - Rattus norvegicus [Reaction:R-MMU-5661125] JMJD6 demethylates Me2sR4-HIST1H4 - Mus musculus [Reaction:R-HSA-5661125] JMJD6 demethylates Me2sR4-HIST1H4 - Homo sapiens [Reaction:R-CEL-5661124] JMJD6 demethylates MeR4-HIST1H4 - Caenorhabditis elegans [Reaction:R-DME-5661124] JMJD6 demethylates MeR4-HIST1H4 - Drosophila melanogaster [Reaction:R-GGA-5661124] JMJD6 demethylates MeR4-HIST1H4 - Gallus gallus [Reaction:R-XTR-5661124] JMJD6 demethylates MeR4-HIST1H4 - Xenopus tropicalis [Reaction:R-DRE-5661124] JMJD6 demethylates MeR4-HIST1H4 - Danio rerio [Reaction:R-SSC-5661124] JMJD6 demethylates MeR4-HIST1H4 - Sus scrofa [Reaction:R-BTA-5661124] JMJD6 demethylates MeR4-HIST1H4 - Bos taurus [Reaction:R-CFA-5661124] JMJD6 demethylates MeR4-HIST1H4 - Canis familiaris [Reaction:R-RNO-5661124] JMJD6 demethylates MeR4-HIST1H4 - Rattus norvegicus [Reaction:R-MMU-5661124] JMJD6 demethylates MeR4-HIST1H4 - Mus musculus [Reaction:R-HSA-5661124] JMJD6 demethylates MeR4-HIST1H4 - Homo sapiens [Reaction:R-CEL-4754181] KDM5A-D demethylate Me2K5-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-4754181] KDM5A-D demethylate Me2K5-histone H3 - Danio rerio [Reaction:R-SSC-4754181] KDM5A-D demethylate Me2K5-histone H3 - Sus scrofa [Reaction:R-BTA-4754181] KDM5A-D demethylate Me2K5-histone H3 - Bos taurus [Reaction:R-CFA-4754181] KDM5A-D demethylate Me2K5-histone H3 - Canis familiaris [Reaction:R-RNO-4754181] KDM5A-D demethylate Me2K5-histone H3 - Rattus norvegicus [Reaction:R-MMU-4754181] KDM5A-D demethylate Me2K5-histone H3 - Mus musculus [Reaction:R-HSA-4754181] KDM5A-D demethylate Me2K5-histone H3 - Homo sapiens [Reaction:R-PFA-5661115] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 - Plasmodium falciparum [Reaction:R-CEL-5661115] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-5661115] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 - Danio rerio [Reaction:R-SSC-5661115] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 - Sus scrofa [Reaction:R-BTA-5661115] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 - Bos taurus [Reaction:R-CFA-5661115] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 - Canis familiaris [Reaction:R-RNO-5661115] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 - Rattus norvegicus [Reaction:R-MMU-5661115] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 - Mus musculus [Reaction:R-HSA-5661115] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 - Homo sapiens [Reaction:R-CEL-5661114] KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-5661114] KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 - Danio rerio [Reaction:R-SSC-5661114] KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 - Sus scrofa [Reaction:R-BTA-5661114] KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 - Bos taurus [Reaction:R-CFA-5661114] KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 - Canis familiaris [Reaction:R-RNO-5661114] KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 - Rattus norvegicus [Reaction:R-MMU-5661114] KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 - Mus musculus [Reaction:R-HSA-5661114] KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 - Homo sapiens [Reaction:R-CEL-5661116] KDM5A-D demethylate Me3K5-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-5661116] KDM5A-D demethylate Me3K5-histone H3 - Danio rerio [Reaction:R-SSC-5661116] KDM5A-D demethylate Me3K5-histone H3 - Sus scrofa [Reaction:R-BTA-5661116] KDM5A-D demethylate Me3K5-histone H3 - Bos taurus [Reaction:R-CFA-5661116] KDM5A-D demethylate Me3K5-histone H3 - Canis familiaris [Reaction:R-RNO-5661116] KDM5A-D demethylate Me3K5-histone H3 - Rattus norvegicus [Reaction:R-MMU-5661116] KDM5A-D demethylate Me3K5-histone H3 - Mus musculus [Reaction:R-HSA-5661116] KDM5A-D demethylate Me3K5-histone H3 - Homo sapiens [Reaction:R-CEL-4754176] JMJD6 demethylates MeR3-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-4754176] JMJD6 demethylates MeR3-histone H3 - Danio rerio [Reaction:R-SSC-4754176] JMJD6 demethylates MeR3-histone H3 - Sus scrofa [Reaction:R-BTA-4754176] JMJD6 demethylates MeR3-histone H3 - Bos taurus [Reaction:R-CFA-4754176] JMJD6 demethylates MeR3-histone H3 - Canis familiaris [Reaction:R-RNO-4754176] JMJD6 demethylates MeR3-histone H3 - Rattus norvegicus [Reaction:R-MMU-4754176] JMJD6 demethylates MeR3-histone H3 - Mus musculus [Reaction:R-HSA-4754176] JMJD6 demethylates MeR3-histone H3 - Homo sapiens [Reaction:R-CEL-4754187] KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 - Caenorhabditis elegans [Reaction:R-DRE-4754187] KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 - Danio rerio [Reaction:R-SSC-4754187] KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 - Sus scrofa [Reaction:R-BTA-4754187] KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 - Bos taurus [Reaction:R-CFA-4754187] KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 - Canis familiaris [Reaction:R-RNO-4754187] KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 - Rattus norvegicus [Reaction:R-MMU-4754187] KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 - Mus musculus [Reaction:R-HSA-4754187] KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 - Homo sapiens [Reaction:R-HSA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Homo sapiens [Reaction:R-HSA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Homo sapiens [Reaction:R-HSA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Homo sapiens [Reaction:R-RNO-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Rattus norvegicus [Reaction:R-RNO-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Rattus norvegicus [Reaction:R-RNO-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Rattus norvegicus [Reaction:R-CFA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Canis familiaris [Reaction:R-CFA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Canis familiaris [Reaction:R-CFA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Canis familiaris [Reaction:R-BTA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Bos taurus [Reaction:R-BTA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Bos taurus [Reaction:R-BTA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Bos taurus [Reaction:R-SSC-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Sus scrofa [Reaction:R-SSC-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Sus scrofa [Reaction:R-SSC-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Sus scrofa [Reaction:R-DRE-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Danio rerio [Reaction:R-DRE-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Danio rerio [Reaction:R-DRE-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Danio rerio [Reaction:R-XTR-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Xenopus tropicalis [Reaction:R-XTR-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Xenopus tropicalis [Reaction:R-XTR-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Xenopus tropicalis [Reaction:R-DME-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Drosophila melanogaster [Reaction:R-DME-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Drosophila melanogaster [Reaction:R-DME-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Drosophila melanogaster [Reaction:R-DDI-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Dictyostelium discoideum [Reaction:R-DDI-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Dictyostelium discoideum [Reaction:R-DDI-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Dictyostelium discoideum [Reaction:R-MMU-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Mus musculus [Reaction:R-MMU-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Mus musculus [Reaction:R-HSA-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Homo sapiens [Reaction:R-HSA-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Homo sapiens [Reaction:R-RNO-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Rattus norvegicus [Reaction:R-RNO-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Rattus norvegicus [Reaction:R-CFA-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Canis familiaris [Reaction:R-CFA-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Canis familiaris [Reaction:R-BTA-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Bos taurus [Reaction:R-BTA-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Bos taurus [Reaction:R-SSC-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Sus scrofa [Reaction:R-SSC-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Sus scrofa [Reaction:R-DRE-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Danio rerio [Reaction:R-DRE-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Danio rerio [Reaction:R-XTR-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Xenopus tropicalis [Reaction:R-XTR-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Xenopus tropicalis [Reaction:R-GGA-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Gallus gallus [Reaction:R-GGA-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Gallus gallus [Reaction:R-DME-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Drosophila melanogaster [Reaction:R-DME-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Drosophila melanogaster [Reaction:R-CEL-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Caenorhabditis elegans [Reaction:R-CEL-1234181] Nuclear PHD1,3 hydroxylates proline residues on HIF1A - Caenorhabditis elegans [Reaction:R-HSA-1234166] Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) - Homo sapiens [Reaction:R-HSA-1234166] Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) - Homo sapiens [Reaction:R-HSA-2172678] PHF8 demethylates histone H4K20me1 - Homo sapiens [Reaction:R-RNO-2172678] PHF8 demethylates histone H4K20me1 - Rattus norvegicus [Reaction:R-CFA-2172678] PHF8 demethylates histone H4K20me1 - Canis familiaris [Reaction:R-BTA-2172678] PHF8 demethylates histone H4K20me1 - Bos taurus [Reaction:R-SSC-2172678] PHF8 demethylates histone H4K20me1 - Sus scrofa [Reaction:R-DRE-2172678] PHF8 demethylates histone H4K20me1 - Danio rerio [Reaction:R-XTR-2172678] PHF8 demethylates histone H4K20me1 - Xenopus tropicalis [Reaction:R-DDI-2172678] PHF8 demethylates histone H4K20me1 - Dictyostelium discoideum [Reaction:R-SPO-2172678] PHF8 demethylates histone H4K20me1 - Schizosaccharomyces pombe [Reaction:R-SCE-2172678] PHF8 demethylates histone H4K20me1 - Saccharomyces cerevisiae [Reaction:R-HSA-5221014] TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine - Homo sapiens [Reaction:R-DME-5625870] KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters - Drosophila melanogaster [Reaction:R-XTR-5625870] KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters - Xenopus tropicalis [Reaction:R-DRE-5625870] KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters - Danio rerio [Reaction:R-SSC-5625870] KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters - Sus scrofa [Reaction:R-BTA-5625870] KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters - Bos taurus [Reaction:R-CFA-5625870] KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters - Canis familiaris [Reaction:R-RNO-5625870] KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters - Rattus norvegicus [Reaction:R-DME-5625848] KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters - Drosophila melanogaster [Reaction:R-XTR-5625848] KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters - Xenopus tropicalis [Reaction:R-DRE-5625848] KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters - Danio rerio [Reaction:R-SSC-5625848] KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters - Sus scrofa [Reaction:R-BTA-5625848] KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters - Bos taurus [Reaction:R-CFA-5625848] KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters - Canis familiaris [Reaction:R-RNO-5625848] KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters - Rattus norvegicus [Reaction:R-DME-5625797] KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters - Drosophila melanogaster [Reaction:R-XTR-5625797] KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters - Xenopus tropicalis [Reaction:R-DRE-5625797] KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters - Danio rerio [Reaction:R-SSC-5625797] KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters - Sus scrofa [Reaction:R-BTA-5625797] KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters - Bos taurus [Reaction:R-CFA-5625797] KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters - Canis familiaris [Reaction:R-RNO-5625797] KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters - Rattus norvegicus [Reaction:R-HSA-5625870] KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters - Homo sapiens [Reaction:R-HSA-5625848] KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters - Homo sapiens [Reaction:R-HSA-5625797] KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters - Homo sapiens
created	[InstanceEdit:113672] Gopinathrao, G, 2004-06-15 18:05:00
crossReference	[DatabaseIdentifier:29407] COMPOUND:C00026
dbId	113671
displayName	2OG [nucleoplasm]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9630008] D'Eustachio, Peter, 2018-11-27
name	2OG 2-Oxoglutarate 2-oxoglutaric acid alpha-ketoglutarate
referenceEntity	[ReferenceMolecule:chebi:16810] 2-oxoglutarate(2-) [ChEBI:16810]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-113671
updateTrackers	[UpdateTracker:9873938] Update Tracker - [SimpleEntity:113671] 2OG [nucleoplasm] - v43:[addName] [UpdateTracker:9891609] Update Tracker - [SimpleEntity:113671] 2OG [nucleoplasm] - v52:[addName] [UpdateTracker:9900330] Update Tracker - [SimpleEntity:113671] 2OG [nucleoplasm] - v68:[add_removeReferenceEntity]

Referrals

(input)

(updatedInstance)

© 2026 Reactome

Cite Us!