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GGA3 [endosome membrane]
Stable Identifier
R-HSA-5692936
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Synonyms
ADP-ribosylation factor-binding protein GGA3, GGA3_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Amyloid fiber formation (Homo sapiens)
BACE1 binds GGA1,2,3 (Homo sapiens)
BACE1:GGA1,2,3 [plasma membrane] (Homo sapiens)
GGA1,2,3 [endosome membrane] (Homo sapiens)
GGA3 [endosome membrane] (Homo sapiens)
GGA1,2,3 [endosome membrane] (Homo sapiens)
GGA3 [endosome membrane] (Homo sapiens)
BACE1:GGA1,2,3 translocates from plasma membrane to endosome (Homo sapiens)
BACE1:GGA1,2,3 [plasma membrane] (Homo sapiens)
GGA1,2,3 [endosome membrane] (Homo sapiens)
GGA3 [endosome membrane] (Homo sapiens)
GGA1,2,3 [endosome membrane] (Homo sapiens)
GGA3 [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NZ52 GGA3
Gene Names
GGA3, KIAA0154
Chain
chain:1-723
Reference Genes
BioGPS Gene:23163 GGA3
COSMIC (genes):GGA3 GGA3
CTD Gene:23163 GGA3
dbSNP Gene:23163 GGA3
ENSEMBL:ENSG00000125447 GGA3
ENSEMBL_homo_sapiens_GENE:ENSG00000125447.18 GGA3
HGNC:17079 GGA3
KEGG Gene (Homo sapiens):23163 GGA3
Monarch:23163 GGA3
NCBI Gene:23163 GGA3
OMIM:606006 GGA3
UCSC:Q9NZ52 GGA3
Reference Transcript
RefSeq:NM_001291642.1 GGA3
RefSeq:NM_014001.4 GGA3
RefSeq:NM_138619.3 GGA3
RefSeq:NM_001172703.2 GGA3
RefSeq:NM_001172704.2 GGA3
RefSeq:NM_001291641.1 GGA3
Other Identifiers
11734365_a_at
11739388_a_at
11746601_a_at
11746602_a_at
11749714_a_at
16848761
209411_PM_s_at
209411_s_at
211815_PM_s_at
211815_s_at
23163
3770664
3770665
3770666
3770667
3770669
3770670
3770672
3770674
3770676
3770677
3770679
3770681
3770682
3770683
3770684
3770685
3770688
3770689
3770697
3770698
37959_at
8018324
A_23_P38181
D63876_at
GE57281
GO:0005515
GO:0005764
GO:0005768
GO:0005769
GO:0005773
GO:0005794
GO:0005802
GO:0006622
GO:0006886
GO:0006893
GO:0008289
GO:0010008
GO:0015031
GO:0016020
GO:0016192
GO:0030163
GO:0031267
GO:0031410
GO:0031647
GO:0031648
GO:0031901
GO:0032456
GO:0032991
GO:0034394
GO:0035091
GO:0043001
GO:0043130
GO:0043226
GO:0044877
GO:0045732
GO:0051641
GO:0055037
GO:0055038
GO:0061462
GO:0072659
GO:0097708
GO:1902430
HMNXSV003022368
HMNXSV003058392
Hs.87726.0.S2_3p_a_at
ILMN_1675982
ILMN_1751135
ILMN_2402972
PH_hs_0004921
TC17001874.hg
TC17002786.hg
g7229485_3p_a_at
Participates
as a member of
GGA1,2,3 [endosome membrane] (Homo sapiens)
Other forms of this molecule
GGA3 [recycling endosome membrane]
GGA3 [early endosome membrane]
Cross References
RefSeq
NP_001166174.1
,
NP_001278570.1
,
NP_054720.1
,
NP_619525.1
,
NP_001166175.1
,
NP_001278571.1
OpenTargets
ENSG00000125447
HPA
ENSG00000125447-GGA3
GeneCards
Q9NZ52
Ensembl
ENST00000649398
,
ENSP00000438085
,
ENST00000538886
,
ENSP00000446421
,
ENST00000578348
,
ENSG00000125447
,
ENSP00000463288
,
ENSP00000462081
,
ENSP00000496890
,
ENST00000582717
,
ENST00000537686
PRO
Q9NZ52
Pharos - Targets
Q9NZ52
HMDB Protein
HMDBP08422
PDB
1P4U
,
1JPL
,
1LF8
,
1JUQ
,
1YD8
,
1WR6
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P11717 IGF2R
7
IGF2R [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869091)
IGF2R [Golgi membrane]
(R-HSA-434345)
IGF2R [cytoplasmic vesicle membrane]
(R-HSA-434213)
IGF2R [transport vesicle]
(R-HSA-6814609)
IGF2R [trans-Golgi network membrane]
(R-HSA-6814608)
IGF2R [plasma membrane]
(R-HSA-6806532)
IGF2R [secretory granule membrane]
(R-HSA-6803320)
0.761
8
UniProt:Q15276 RABEP1
1
RABEP1 [early endosome membrane]
(R-HSA-2029004)
0.698
12
UniProt:P84080
2
ARF1 [cytosol]
(R-BTA-200826)
ARF1 [Golgi membrane]
(R-BTA-199971)
0.646
3
UniProt:Q13258 PTGDR
1
PTGDR [plasma membrane]
(R-HSA-391830)
0.61
5
UniProt:P62330 ARF6
2
ARF6 [recycling endosome membrane]
(R-HSA-2029049)
ARF6 [cytosol]
(R-HSA-8871121)
0.589
3
UniProt:P20645 M6PR
6
M6PR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869100)
M6PR [plasma membrane]
(R-HSA-8864564)
M6PR [Golgi membrane]
(R-HSA-429824)
M6PR [lysosomal membrane]
(R-HSA-432696)
M6PR [trans-Golgi network membrane]
(R-HSA-6814611)
M6PR [transport vesicle]
(R-HSA-6814613)
0.573
2
UniProt:Q6VY07 PACS1
1
PACS1 [cytosol]
(R-HSA-167634)
0.544
5
UniProt:P56817 BACE1
8
BACE1 [endoplasmic reticulum lumen]
(R-HSA-6783326)
7K-BACE1 [endoplasmic reticulum lumen]
(R-HSA-5693006)
BACE1(22-45) [Golgi-associated vesicle lumen]
(R-HSA-5693069)
7K-BACE1 [Golgi-associated vesicle lumen]
(R-HSA-5693095)
7K-BACE1(46-501) [Golgi-associated vesicle lumen]
(R-HSA-5693106)
BACE1(46-501) [Golgi-associated vesicle lumen]
(R-HSA-5693105)
BACE1(46-501) [plasma membrane]
(R-HSA-5692933)
BACE1 [endosome membrane]
(R-HSA-5692942)
0.544
2
UniProt:P18272 NCAP
0.524
2
UniProt:Q9UJY4 GGA2
2
GGA2 [early endosome membrane]
(R-HSA-8854140)
GGA2 [endosome membrane]
(R-HSA-5692937)
0.508
3
UniProt:P0CG47 UBB
20
UBB(77-152) [endocytic vesicle membrane]
(R-HSA-939253)
UBB(1-76) [endocytic vesicle membrane]
(R-HSA-939231)
UBB(153-228) [endocytic vesicle membrane]
(R-HSA-939171)
Ub-33-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783023)
Ub-109-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783008)
Ub-185-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783046)
Ub-215-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783002)
Ub-63-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783148)
Ub-139-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783012)
Ub-158-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783162)
Ub-6-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783014)
Ub-82-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783015)
Ub-163-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783025)
Ub-87-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6782998)
Ub-11-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783109)
Ub-124-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783131)
Ub-200-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783100)
Ub-48-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783165)
Ub-181-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783160)
Ub-29-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783070)
0.508
2
UniProt:Q9UJY5 GGA1
2
GGA1 [early endosome membrane]
(R-HSA-8854136)
GGA1 [endosome membrane]
(R-HSA-5692930)
0.508
4
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