Reactome | PACS1 [cytosol]

PACS1 [cytosol]

Stable Identifier

R-HSA-167634

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

PACS-1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q6VY07 PACS1

Gene Names

PACS1, KIAA1175

Chain

initiator methionine:, chain:2-963

Reference Genes

BioGPS Gene:55690 PACS1

COSMIC (genes):PACS1 PACS1

CTD Gene:55690 PACS1

dbSNP Gene:55690 PACS1

ENSEMBL:ENSG00000175115 PACS1

HGNC:30032 PACS1

KEGG:hsa:55690 PACS1

Monarch:55690 PACS1

NCBI Gene:55690 PACS1

OMIM:607492 PACS1

UCSC:Q6VY07 PACS1

Reference Transcript

RefSeq:NM_018026.3 PACS1

Other Identifiers

11717030_x_at

11749799_a_at

16727277

220557_3p_s_at

220557_PM_s_at

220557_s_at

224658_3p_x_at

224658_PM_x_at

224658_x_at

231222_PM_at

231222_at

3335953

3335954

3335955

3335986

3335990

3335991

3335992

3335993

3335994

3335995

3335996

3335997

3335998

3335999

3336000

3336001

3336002

3336003

3336004

3336005

3336008

3336010

3336012

3336014

3336015

3336016

3336017

3336019

3336020

3336021

3336022

3336023

3336025

3336026

3336027

3336028

3336029

3336030

3336031

3336032

3336033

3336034

48875_at

55690

70971_at

7941537

A_14_P104376

A_14_P111730

A_23_P47220

A_23_P500282

A_24_P69784

GE53812

GE82276

GO:0002260

GO:0002376

GO:0005515

GO:0005794

GO:0005829

GO:0030137

GO:0031410

GO:0034067

GO:0043226

GO:0044325

GO:0072659

HMNXSV003047612

Hs.210848.0.A1_3p_at

Hs.260150.1.S1_3p_a_at

ILMN_1716488

PH_hs_0003768

TC11000654.hg

g8922284_3p_a_at

g8922284_3p_x_at

Participates

as an output of

Degradation of MHC I Complex (Homo sapiens)

as a component of

as an input of

Formation of MHC I:Nef:AP-1:PACS-1 Complex (Homo sapiens)

Cross References

ENSEMBL

ENST00000320580, ENSP00000316454

OpenTargets

ENSG00000175115

HPA

ENSG00000175115-PACS1

PRO

Q6VY07

Pharos - Targets

Q6VY07

GlyGen

Q6VY07

Orphanet

PACS1

HMDB Protein

HMDBP10752

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P67870 CSNK2B	5	CSNK2B [cytosol] (R-HSA-201693) CSNK2B [nucleoplasm] (R-HSA-6805067) CSNK2B [secretory granule lumen] (R-HSA-6801319) CSNK2B [extracellular region] (R-HSA-6806508) CSNK2B [ficolin-1-rich granule lumen] (R-HSA-6801290)	0.593	3
UniProt:A0A6Q8PF08 A0A6Q8PF08			0.556	3
UniProt:P54253 ATX1			0.556	6
IntAct:EBI-25865403 EHD27213144			0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:Q92870-2 Q928702			0.556	3
UniProt:Q13148 TADBP			0.556	6
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	18
UniProt:P37840 SNCA	5	SNCA [cytosol] (R-HSA-5658500) p-S129-SNCA [cytosol] (R-HSA-9836432) Ub-SNCA [cytosol] (R-HSA-5660754) SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569)	0.556	3
UniProt:Q9NZ52 GGA3	3	GGA3 [endosome membrane] (R-HSA-5692936) GGA3 [early endosome membrane] (R-HSA-8854137) GGA3 [recycling endosome membrane] (R-HSA-8875655)	0.544	5
UniProt:P23470 PTPRG			0.534	2
UniProt:Q04917 YWHAH	1	YWHAH [cytosol] (R-HSA-1445107)	0.527	2
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.527	2
UniProt:Q9Y2I8 WDR37			0.527	5
UniProt:Q15435 PP1R7			0.508	2

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