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IGF2R [cytoplasmic vesicle membrane]
Stable Identifier
R-HSA-434213
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytoplasmic vesicle membrane
Synonyms
Cation-independent mannose-6-phosphate receptor, MPRI_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Golgi Associated Vesicle Biogenesis (Homo sapiens)
trans-Golgi Network Derived Vesicle Uncoating (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [cytoplasmic vesicle membrane] (Homo sapiens)
Golgi-associated Vesicle Cargo [cytoplasmic vesicle membrane] (Homo sapiens)
IGF2R [cytoplasmic vesicle membrane] (Homo sapiens)
Golgi-associated Vesicle Cargo [cytoplasmic vesicle membrane] (Homo sapiens)
IGF2R [cytoplasmic vesicle membrane] (Homo sapiens)
trans-Golgi Network Vesicle Scission (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [cytoplasmic vesicle membrane] (Homo sapiens)
Golgi-associated Vesicle Cargo [cytoplasmic vesicle membrane] (Homo sapiens)
IGF2R [cytoplasmic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P11717 IGF2R
Gene Names
IGF2R, MPRI
Chain
signal peptide:1-40, chain:41-2491
Reference Genes
BioGPS Gene:3482 IGF2R
COSMIC (genes):IGF2R IGF2R
CTD Gene:3482 IGF2R
dbSNP Gene:3482 IGF2R
ENSEMBL:ENSG00000197081 IGF2R
ENSEMBL_homo_sapiens_GENE:ENSG00000197081.16 IGF2R
HGNC:5467 IGF2R
KEGG Gene (Homo sapiens):3482 IGF2R
Monarch:3482 IGF2R
NCBI Gene:3482 IGF2R
OMIM:147280 IGF2R
UCSC:P11717 IGF2R
Reference Transcript
RefSeq:NM_000876.3 IGF2R
Other Identifiers
11716128_at
11716129_at
11753961_a_at
1569052_PM_at
1569052_at
160027_s_at
17014364
201392_PM_s_at
201392_s_at
201393_PM_s_at
201393_s_at
2934310
2934311
2934312
2934314
2934319
2934320
2934322
2934327
2934329
2934332
2934339
2934340
2934341
2934349
2934351
2934352
2934353
2934354
2934355
2934360
2934361
2934362
2934363
2934365
2934367
2934368
2934370
2934372
2934373
2934374
2934375
2934377
2934379
2934381
2934382
2934383
2934384
2934388
2934391
2934392
2934394
2934395
2934397
2934398
2934401
2934402
2934403
2934405
2934407
2934408
2934409
2934428
2934429
2934431
2934432
2934433
2934435
2934436
2934437
2934438
2934439
2934440
2934442
2934443
2934445
2934447
2934449
2934450
3482
8123181
972_s_at
A_14_P119493
A_23_P156953
A_23_P334021
GE60227
GE613451
GO:0000139
GO:0001889
GO:0001965
GO:0001972
GO:0003824
GO:0005010
GO:0005515
GO:0005520
GO:0005537
GO:0005576
GO:0005615
GO:0005634
GO:0005635
GO:0005641
GO:0005768
GO:0005769
GO:0005770
GO:0005794
GO:0005802
GO:0005886
GO:0005925
GO:0006898
GO:0007041
GO:0007165
GO:0007186
GO:0007283
GO:0008289
GO:0009791
GO:0009986
GO:0010008
GO:0012501
GO:0016020
GO:0016192
GO:0016740
GO:0019899
GO:0022414
GO:0023052
GO:0030118
GO:0030133
GO:0030139
GO:0030140
GO:0030667
GO:0030669
GO:0031100
GO:0031410
GO:0031995
GO:0032526
GO:0032588
GO:0038023
GO:0042802
GO:0042981
GO:0043065
GO:0043226
GO:0044794
GO:0048009
GO:0048471
GO:0048856
GO:0051219
GO:0060089
GO:0070062
GO:0140096
GO:1904772
GO:1905394
HMNXSV003007415
Hs.76473.0.S1_3p_a_at
Hs2.391924.1.S1_3p_at
Hs2.391924.1.S1_3p_x_at
ILMN_1807662
PH_hs_0004415
PH_hs_0018933
TC06001152.hg
Y00285_s_at
g4504610_3p_a_at
Participates
as a candidate of
Golgi-associated Vesicle Cargo [cytoplasmic vesicle membrane] (Homo sapiens)
Other forms of this molecule
IGF2R [clathrin-coated endocytic vesicle membrane]
IGF2R [Golgi membrane]
IGF2R [transport vesicle]
IGF2R [trans-Golgi network membrane]
IGF2R [plasma membrane]
IGF2R [secretory granule membrane]
Inferred To
Igf2r [cytoplasmic vesicle membrane]
(Mus musculus)
Igf2r [cytoplasmic vesicle membrane]
(Rattus norvegicus)
Lerp [cytoplasmic vesicle membrane]
(Drosophila melanogaster)
IGF2R [cytoplasmic vesicle membrane]
(Bos taurus)
IGF2R [cytoplasmic vesicle membrane]
(Dictyostelium discoideum)
IGF2R [cytoplasmic vesicle membrane]
(Gallus gallus)
IGF2R [cytoplasmic vesicle membrane]
(Sus scrofa)
igf2r [cytoplasmic vesicle membrane]
(Xenopus tropicalis)
CI-MPR/IGF2R [cytoplasmic vesicle membrane]
(Canis familiaris)
Cross References
RefSeq
NP_000867.2
OpenTargets
ENSG00000197081
HPA
ENSG00000197081-IGF2R
GeneCards
P11717
ZINC - Substances
MPRI_HUMAN
ZINC target
P11717
Ensembl
ENSG00000197081
,
ENSP00000349437
,
ENST00000356956
PRO
P11717
Pharos - Targets
P11717
ZINC - Predictions - Purchasable
MPRI_HUMAN
HMDB Protein
HMDBP01754
PDB
1JWG
,
2L29
,
8AFZ
,
6Z31
,
2M68
,
1GP0
,
6Z30
,
1GP3
,
6V02
,
2M6T
,
1GQB
,
6N5Y
,
6N5X
,
2V5P
,
2CNJ
,
1E6F
,
1JPL
,
2L2A
,
2V5O
,
5IEI
,
6Z32
,
6P8I
,
2V5N
,
1LF8
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NZ52 GGA3
3
GGA3 [endosome membrane]
(R-HSA-5692936)
GGA3 [recycling endosome membrane]
(R-HSA-8875655)
GGA3 [early endosome membrane]
(R-HSA-8854137)
0.761
8
UniProt:P27824 CANX
2
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
0.483
2
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