Reactome | SPPL2B [plasma membrane]

Stable Identifier

R-HSA-8863116

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

fullName evidence="14 17"Signal peptide peptidase-like 2B, SPP2B_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8TCT7 SPPL2B

Gene Names

SPPL2B, IMP4, KIAA1532, PSL1

Chain

signal peptide:1-25, chain:26-592

Reference Genes

COSMIC (genes):IMP4 SPPL2B

COSMIC (genes):SPPL2B SPPL2B

dbSNP Gene:56928 SPPL2B

ENSEMBL:ENSG00000005206 SPPL2B

Participates

as a member of

Inferred To

Sppl2b [plasma membrane] (Mus musculus)

Sppl2b [plasma membrane] (Rattus norvegicus)

sppl2b [plasma membrane] (Xenopus tropicalis)

SPPL2B [plasma membrane] (Bos taurus)

SPPL2B [plasma membrane] (Canis familiaris)

SPPL2B [plasma membrane] (Sus scrofa)

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBQ6 EXTL2	1	EXTL2 [endoplasmic reticulum membrane] (R-HSA-8953372)	0.527	3
UniProt:P24468 NR2F2	1	NR2F2 [nucleoplasm] (R-HSA-1183002)	0.527	2
UniProt:O14949 UQCRQ	1	UQCRQ [mitochondrial inner membrane] (R-HSA-164283)	0.527	3
UniProt:Q9UL46 PSME2	2	PSME2 [nucleoplasm] (R-HSA-174350) PSME2 [cytosol] (R-HSA-68814)	0.527	2
UniProt:Q7Z434 MAVS	2	MAVS [mitochondrial outer membrane] (R-HSA-913730) K48polyUb-MAVS [mitochondrial outer membrane] (R-HSA-983463)	0.527	2
UniProt:Q9BY67 CADM1	1	CADM1 [plasma membrane] (R-HSA-420589)	0.527	3
UniProt:O43909 EXTL3	1	EXTL3 [endoplasmic reticulum membrane] (R-HSA-535476)	0.527	2
UniProt:P27824 CANX	2	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091)	0.527	2
UniProt:Q9HD23 MRS2	1	MRS2 [mitochondrial inner membrane] (R-HSA-5216072)	0.527	3
UniProt:Q496F6 CD300E	1	CD300E [plasma membrane] (R-HSA-2130162)	0.527	2
UniProt:Q7Z7B1 PIGW	1	PIGW [endoplasmic reticulum membrane] (R-HSA-162693)	0.527	2
UniProt:O95427 PIGN	1	PIGN [endoplasmic reticulum membrane] (R-HSA-162724)	0.527	4
UniProt:Q8TAD4 SLC30A5	2	SLC30A5 [secretory granule membrane] (R-HSA-437105) SLC30A5 [Golgi membrane] (R-HSA-9817559)	0.527	4

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