FURIN [plasma membrane]

Stable Identifier
R-HSA-2159856
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Furin
FURIN [plasma membrane] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
1629222 Activation of human furin precursor processing endoprotease occurs by an intramolecular autoproteolytic cleavage

Leduc, R, Molloy, S S, Thorne, BA, Thomas, G

J Biol Chem 1992
External Reference Information
External Reference
Gene Names
FURIN, FUR, PACE, PCSK3
Chain
signal peptide:1-26, propeptide:27-107, chain:108-794
Other Identifiers
0004780672
11716282_s_at
16804942
201945_PM_at
201945_at
35338_at
3608399
3608401
3608402
3608404
3608405
3608406
3608407
3608408
3608409
3608411
3608412
3608413
3608414
3608415
3608417
3608418
3608420
3608421
3608422
3608423
3608424
3608425
3608426
3608428
3608429
3608430
3608431
3608432
5045
7986092
A_23_P3368
GO:0000139
GO:0001825
GO:0002020
GO:0002376
GO:0002862
GO:0003674
GO:0004175
GO:0004252
GO:0004867
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005768
GO:0005783
GO:0005794
GO:0005796
GO:0005802
GO:0005886
GO:0006465
GO:0006508
GO:0006810
GO:0006950
GO:0007165
GO:0007179
GO:0008150
GO:0008201
GO:0008233
GO:0008236
GO:0009056
GO:0009058
GO:0009790
GO:0009966
GO:0009986
GO:0010008
GO:0010951
GO:0016020
GO:0016021
GO:0016485
GO:0016486
GO:0016787
GO:0019058
GO:0019082
GO:0019899
GO:0022617
GO:0030140
GO:0030173
GO:0030198
GO:0030234
GO:0030574
GO:0031410
GO:0031638
GO:0032374
GO:0032804
GO:0032902
GO:0032911
GO:0032940
GO:0034641
GO:0042176
GO:0042277
GO:0043043
GO:0043167
GO:0043226
GO:0045121
GO:0046872
GO:0048406
GO:0048646
GO:0048856
GO:0051004
GO:0051044
GO:0051604
GO:0052548
GO:0070062
GO:0090472
GO:1901394
GO:1904399
GO:1990000
HMNXSV003039920
ILMN_1790228
PH_hs_0003807
TC15000870.hg
TC15002368.hg
X17094_at
g4505578_3p_at
Participates
This entity regulates
Other forms of this molecule
Inferred To
Cross References
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
IntEnz
GeneCards
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (6)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P0DTC2 S  16 0.854 5
 UniProt:O14793 MSTN  1 0.623 2
 UniProt:K9N5Q8 SPIKE      0.623 3
 UniProt:P50281 MMP14  3 0.564 3
 UniProt:Q9H239 MMP28      0.556 3
 UniProt:P05067 APP  20 0.556 3
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