di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment]

Stable Identifier
R-COV-9696920
Type
Protein [EntityWithAccessionedSequence]
Species
Severe acute respiratory syndrome coronavirus 2
Compartment
endoplasmic reticulum-Golgi intermediate compartment
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
32366695 Site-specific glycan analysis of the SARS-CoV-2 spike

Watanabe, Y, Allen, JD, Wrapp, D, McLellan, JS, Crispin, M

Science 2020
External Reference Information
External Reference
UniProt:P0DTC2 S
Gene Names
S, 2
Chain
signal peptide:1-12, chain:13-1273, chain:13-685, chain:686-1273, chain:816-1273
Reference Genes
BioGPS Gene:43740568 S
Monarch:43740568 S
NCBI Gene:43740568 S
Reference Transcript
Participant Of
hasComponent
Other forms of this molecule
fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment]
tri-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment]
high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment]
nascent Spike [endoplasmic reticulum lumen]
14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen]
Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen]
high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen]
high-mannose N-glycan folded Spike [endoplasmic reticulum lumen]
high-mannose N-glycan-PALM-Spike [endoplasmic reticulum lumen]
complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane]
complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane]
complex N-glycan-PALM-Spike S1 Fragment [virion membrane]
complex N-glycan-PALM-Spike S2 Fragment [virion membrane]
fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane]
fully glycosylated Spike [virion membrane]
Modified Residues
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 1074
Coordinate
1074
Modification
high-mannose N-glycan-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 122
Coordinate
122
Modification
high-mannose N-glycan-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 603
Coordinate
603
Modification
high-mannose N-glycan-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 61
Coordinate
61
Modification
high-mannose N-glycan-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 709
Coordinate
709
Modification
high-mannose N-glycan-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 717
Coordinate
717
Modification
high-mannose N-glycan-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 801
Coordinate
801
Modification
high-mannose N-glycan-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (Man(9) N-glycan group) at 234
Coordinate
234
Modification
Man(9) N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
palmitoylated-L-cysteine at unknown position
PsiMod Name
palmitoylated-L-cysteine
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to a palmitoylated-L-cysteine, such as N-palmitoyl-L-cysteine or S-palmitoyl-L-cysteine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 1098
Coordinate
1098
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 1134
Coordinate
1134
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 1158
Coordinate
1158
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 1173
Coordinate
1173
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 1194
Coordinate
1194
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 149
Coordinate
149
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 165
Coordinate
165
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 17
Coordinate
17
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 282
Coordinate
282
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 331
Coordinate
331
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 343
Coordinate
343
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 616
Coordinate
616
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 657
Coordinate
657
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (di-antennary complex N-glycan group) at 74
Coordinate
74
Modification
di-antennary complex N-glycan group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Disease
Name Identifier Synonyms
COVID-19 0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Cross References
RefSeq
PDB
Interactors (14)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9BYF1 ACE2  5 0.991 84
 UniProt:P0DTC2 S  16 0.937 13
 UniProt:P09958 FURIN  4 0.801 4
 UniProt:Q9H2X3 CLC4M      0.71 5
 UniProt:Q9NNX6 CD209  1 0.683 4
 UniProt:Q7Z5G4 GOLGA7  3 0.643 3
 UniProt:Q9C0B5 ZDHC5      0.643 3
 UniProt:P35613 BSG  2 0.618 5
 UniProt:Q8IUN9-2 CLEC10A      0.558 3
 UniProt:Q61830 Mrc1  4 0.558 2
 lipopolysaccharide [ChEBI:16412]  5 0.558 3
 cholesterol [ChEBI:16113]  20 0.558 3
 UniProt:Q96D42 HAVR1      0.524 5
 linoleic acid [ChEBI:17351]  6 0.522 2
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