Reactome | nascent Spike [endoplasmic reticulum lumen]

6VSB, 6ZP1, 7BZ5, 6ZER, 6ZOX, 6X2A, 7C2L, 6ZOZ, 6X2C, 6XS6, 6XC2, 6M17, 7C8V, 6W41, 6ZGG, 6XEY, 6WPT, 6VYB, 6ZFO, 6XKL, 6YZ7, 7C01, 6XR8, 6XCN, 6M1V, 6LZG, 6XC3, 6XC7, 6LVN, 6X6P, 6LXT, 7BYR, 6YLA, 6ZP2, 6X29, 6ZOY, 6XDG, 7C8W, 6X2B, 6ZCZ, 6YOR, 6VXX, 6ZGE, 6WPS, 6XRA, 6ZP0, 6M0J, 7BWJ, 6ZGI, 6YZ5, 6Z2M, 6VW1, 6XCM, 6XE1, 6XC4, 6Z43, 6YM0, 6ZDH, 7CAN

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BYF1 ACE2	5	ACE2 [endocytic vesicle membrane] (R-HSA-9698958) ACE2(18-805) [plasma membrane] (R-HSA-2022344) glycosylated-ACE2 [endocytic vesicle membrane] (R-HSA-9686721) glycosylated-ACE2 [plasma membrane] (R-HSA-9683480) ACE2 [endoplasmic reticulum lumen] (R-HSA-9683474)	0.991	84
UniProt:P0DTC2 S	16	tri-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9697006) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696997) di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696920) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696943) nascent Spike [endoplasmic reticulum lumen] (R-COV-9694796) 14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9694459) Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696892) high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696875) high-mannose N-glycan folded Spike [endoplasmic reticulum lumen] (R-COV-9696880) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum lumen] (R-COV-9696917) complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] (R-COV-9694343) complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] (R-COV-9694745) complex N-glycan-PALM-Spike S1 Fragment [virion membrane] (R-COV-9694638) complex N-glycan-PALM-Spike S2 Fragment [virion membrane] (R-COV-9694791) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698330) fully glycosylated Spike [virion membrane] (R-COV-9698327)	0.937	13
UniProt:P09958 FURIN	4	FURIN [Golgi lumen] (R-HSA-448351) FURIN [plasma membrane] (R-HSA-2159856) FURIN [extracellular region] (R-HSA-1181103) FURIN [Golgi membrane] (R-HSA-157049)	0.801	4
UniProt:Q9H2X3 CLC4M			0.71	5
UniProt:Q9NNX6 CD209	1	CD209 [plasma membrane] (R-HSA-2079928)	0.683	4
UniProt:Q7Z5G4 GOLGA7	3	GOLGA7 [tertiary granule lumen] (R-HSA-6800164) GOLGA7 [extracellular region] (R-HSA-6800449) GOLGA7 [Golgi membrane] (R-HSA-9647777)	0.643	3
UniProt:Q9C0B5 ZDHC5			0.643	3
UniProt:P35613 BSG	2	BSG [Golgi membrane] (R-HSA-204478) BSG [plasma membrane] (R-HSA-197673)	0.618	5
UniProt:Q8IUN9-2 CLEC10A			0.558	3
UniProt:Q61830 Mrc1	4	Mrc1 [plasma membrane] (R-MMU-1216515) Mrc1 [plasma membrane] (R-MMU-1236776) Mrc1 [clathrin-coated endocytic vesicle membrane] (R-MMU-1236818) Mrc1 [early endosome membrane] (R-MMU-1236785)	0.558	2
lipopolysaccharide [ChEBI:16412]	5	LPS [cell wall] (R-ALL-6803081) LPS [endocytic vesicle lumen] (R-ALL-2239413) LPS [endosome lumen] (R-ALL-2201311) LPS [plasma membrane] (R-ALL-433850) LPS [extracellular region] (R-ALL-166005)	0.558	3
cholesterol [ChEBI:16113]	20	CHOL [lipid droplet] (R-ALL-163586) cholesterol [endocytic vesicle lumen] (R-ALL-2239405) CHOL [lysosomal membrane] (R-ALL-8876478) cholesterol [endosome lumen] (R-ALL-171083) cholesterol [endosome membrane] (R-ALL-171135) cholesterol [clathrin-coated endocytic vesicle membrane] (R-ALL-171069) CHOL [smooth endoplasmic reticulum] (R-ALL-8866305) CHOL [lysosomal lumen] (R-ALL-8848047) CHOL [mitochondrial matrix] (R-ALL-193840) CHOL [transport vesicle membrane] (R-ALL-216762) CHOL [early endosome] (R-ALL-2429660) CHOL [endoplasmic reticulum lumen] (R-ALL-174672) CHOL [cornified envelope] (R-ALL-8847704) CHOL [mitochondrial outer membrane] (R-ALL-8951853) CHOL [cytosol] (R-ALL-176478) cholesterol [mitochondrial intermembrane space] (R-ALL-196084) CHOL [mitochondrial inner membrane] (R-ALL-193156) CHOL [plasma membrane] (R-ALL-171095) CHOL [endoplasmic reticulum membrane] (R-ALL-193384) CHOL [extracellular region] (R-ALL-171149)	0.558	3
UniProt:Q96D42 HAVR1			0.524	5
linoleic acid [ChEBI:17351]	6	LINA [cytosol] (R-ALL-1132021) LINA [endoplasmic reticulum lumen] (R-ALL-2046044) LINA [extracellular region] (R-ALL-879520) LINA [early endosome] (R-ALL-879655) LINA [lipid droplet] (R-ALL-2864095) LINA [nucleoplasm] (R-ALL-400158)	0.522	2