Reactome | CD209 [plasma membrane]

CD209 [plasma membrane]

Stable Identifier

R-HSA-2079928

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

DC-SIGN, CD209 antigen, CD209_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NNX6 CD209

Gene Names

CD209, CLEC4L

Chain

chain:1-404

Reference Genes

BioGPS Gene:30835 CD209

COSMIC (genes):CD209 CD209

CTD Gene:30835 CD209

dbSNP Gene:30835 CD209

ENSEMBL:ENSG00000090659 CD209

ENSEMBL:ENSG00000090659.18 CD209

HGNC:1641 CD209

KEGG Gene (Homo sapiens):30835 CD209

Monarch:30835 CD209

NCBI Gene:30835 CD209

OMIM:604672 CD209

UCSC:Q9NNX6 CD209

Reference Transcript

Other Identifiers

11731871_a_at

11731872_x_at

11731873_a_at

11741961_a_at

1555729_PM_a_at

1555729_a_at

16868000

207277_PM_at

207277_at

207278_PM_s_at

207278_s_at

30835

3819136

3819137

3819138

3819139

3819140

3819144

3848541

3848542

3848543

3848544

3848545

3848546

3848547

3848549

3848550

3848551

3848552

3848553

3848554

3848555

3848556

3848557

3848558

3848559

3848560

4131489

57461_at

8033445

A_24_P186539

A_24_P305345

A_33_P3272493

GE82595

GO:0001618

GO:0002250

GO:0002376

GO:0005515

GO:0005537

GO:0005576

GO:0005737

GO:0005886

GO:0006897

GO:0006955

GO:0007155

GO:0007157

GO:0007159

GO:0009897

GO:0009986

GO:0009988

GO:0016020

GO:0016192

GO:0019062

GO:0019079

GO:0019882

GO:0023052

GO:0030246

GO:0035556

GO:0042102

GO:0042129

GO:0042605

GO:0043657

GO:0045087

GO:0046718

GO:0046790

GO:0046872

GO:0046968

GO:0075733

GO:0097323

GO:0098542

GO:1903902

HMNXSV003047786

HMNXSV003056820

ILMN_1676372

PH_hs_0014301

TC19001118.hg

TC19002313.hg

g10863956_3p_s_at

g13383467_3p_at

Participates

as a component of

as an input of

Inferred To

CD209 [plasma membrane] (Danio rerio)

CD209 [plasma membrane] (Gallus gallus)

Cd209e [plasma membrane] (Mus musculus)

Cd209e [plasma membrane] (Rattus norvegicus)

BEST:GH10831 [plasma membrane] (Drosophila melanogaster)

clec-1 [plasma membrane] (Caenorhabditis elegans)

Homologues of CD209 [plasma membrane] (Danio rerio)

Homologues of CD209 [plasma membrane] (Gallus gallus)

Cross References

RefSeq

NP_066978.1, NP_001138368.1, NP_001138369.1, NP_001138366.1, NP_001138367.1, NP_001138365.1

Guide to Pharmacology - Targets

2930

OpenTargets

ENSG00000090659

HPA

ENSG00000090659-CD209

GeneCards

Q9NNX6

ZINC target

Q9NNX6

Ensembl

ENSP00000315407, ENST00000602261, ENST00000354397, ENSP00000315477, ENSP00000377716, ENST00000204801, ENSP00000204801, ENST00000394161, ENSP00000470658, ENSP00000471137, ENST00000315591, ENSP00000468827, ENST00000601256, ENSG00000090659, ENST00000315599, ENST00000601951, ENSP00000346373

PRO

Q9NNX6

Pharos - Targets

Q9NNX6

HMDB Protein

HMDBP02780

PDB

7NL6, 2B6B, 1SL5, 2IT5, 6GHV, 2XR5, 2IT6, 1K9I, 2XR6, 7NL7, 1SL4

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC2 S	20	S(686-815) [plasma membrane] (R-COV-9770188) Spike S2' Fragment [plasma membrane] (R-COV-9770189) S1 [plasma membrane] (R-COV-9769950) fully glycosylated Spike [plasma membrane] (R-COV-9733472) nascent Spike [endoplasmic reticulum lumen] (R-COV-9694796) 14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9694459) Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696892) high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696875) high-mannose N-glycan folded Spike [endoplasmic reticulum lumen] (R-COV-9696880) high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9766369) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696943) di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696920) tri-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9697006) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696997) complex N-glycan-PALM-Spike S2 Fragment [plasma membrane] (R-COV-9769952) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698330) fully glycosylated Spike [virion membrane] (R-COV-9698327) complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] (R-COV-9694745) complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] (R-COV-9694343) complex N-glycan-PALM-Spike S2 Fragment [virion membrane] (R-COV-9694791)	0.888	12
UniProt:Q08AM6 VAC14	3	VAC14 [Golgi membrane] (R-HSA-1806235) VAC14 [early endosome membrane] (R-HSA-1806207) VAC14 [late endosome membrane] (R-HSA-1806219)	0.666	4
UniProt:Q03463-PRO_0000278734			0.544	2

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