Reactome | CD209 [plasma membrane]

CD209 [plasma membrane]

Stable Identifier

R-HSA-2079928

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

DC-SIGN, CD209 antigen, CD209_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NNX6 CD209

Gene Names

CD209, CLEC4L

Chain

chain:1-404

Reference Genes

BioGPS Gene:30835 CD209

COSMIC - genes:CD209 CD209

CTD Gene:30835 CD209

dbSNP Gene:30835 CD209

ENSEMBL:ENSG00000090659 CD209

HGNC:1641 CD209

KEGG:hsa:30835 CD209

Monarch:30835 CD209

NCBI Gene:30835 CD209

OMIM:604672 CD209

UCSC:Q9NNX6 CD209

Reference Transcript

Participates

as a component of

as an input of

as a member of

Other forms of this molecule

CD209 [endosome membrane]

Inferred To

si:dkey-9i23.5 [plasma membrane] (Danio rerio)

cd209 [plasma membrane] (Danio rerio)

Cd209a [plasma membrane] (Rattus norvegicus)

si:ch73-343l4.8 [plasma membrane] (Danio rerio)

CD209 [plasma membrane] (Danio rerio)

CD209 [plasma membrane] (Mus musculus)

si:ch73-111e15.1 [plasma membrane] (Danio rerio)

si:ch73-122g19.1 [plasma membrane] (Danio rerio)

si:dkey-9i23.4 [plasma membrane] (Danio rerio)

Homologues of CD209 [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_001138366.1, NP_001138365.1, NP_001138368.1, NP_066978.1, NP_001138367.1, NP_001138369.1

Guide to Pharmacology - Targets

2930

OpenTargets

ENSG00000090659

ENSEMBL

ENSP00000346373, ENSP00000377716, ENST00000315599, ENSP00000315477, ENST00000602261, ENST00000204801, ENSP00000470658, ENSP00000471137, ENSG00000090659, ENSP00000204801, ENSP00000468827, ENST00000394161, ENST00000601951, ENSP00000315407, ENST00000601256, ENST00000354397, ENST00000315591

ZINC - Substances

CD209_HUMAN

ZINC target

Q9NNX6

PRO

Q9NNX6

GlyGen

Q9NNX6

PDB

6GHV, 2IT5, 2IT6, 2B6B, 1K9I, 1SL5, 1SL4, 9EMR, 2XR5, 2XR6, 9EMS, 9EMQ, 7NL6, 7NL7

HPA

ENSG00000090659-CD209

GeneCards

CD209

Pharos - Targets

Q9NNX6

HMDB Protein

HMDBP02780

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC2 S	20	S(686-815) [plasma membrane] (R-COV-9770188) Spike S2' Fragment [plasma membrane] (R-COV-9770189) S1 [plasma membrane] (R-COV-9769950) fully glycosylated Spike [plasma membrane] (R-COV-9733472) nascent Spike [endoplasmic reticulum lumen] (R-COV-9694796) 14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9694459) Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696892) high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696875) high-mannose N-glycan folded Spike [endoplasmic reticulum lumen] (R-COV-9696880) high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9766369) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696943) di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696920) fully glycosylated Spike [virion membrane] (R-COV-9698327) complex N-glycan-PALM-Spike S1 Fragment [virion membrane] (R-COV-9694638) complex N-glycan-PALM-Spike S2 Fragment [virion membrane] (R-COV-9694791) complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] (R-COV-9694343) complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] (R-COV-9694745) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698330) complex N-glycan-PALM-Spike S2 Fragment [plasma membrane] (R-COV-9769952) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696997)	0.848	11
UniProt:Q08AM6 VAC14	3	VAC14 [Golgi membrane] (R-HSA-1806235) VAC14 [early endosome membrane] (R-HSA-1806207) VAC14 [late endosome membrane] (R-HSA-1806219)	0.666	4
UniProt:Q03463-PRO_0000278734			0.544	2

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