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HMGCL(1-325) [cytosol]
Stable Identifier
R-HSA-9033112
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Hydroxymethylglutaryl-CoA lyase, mitochondrial, HMGCL_HUMAN
Locations in the PathwayBrowser
Expand all
Protein localization (Homo sapiens)
Peroxisomal protein import (Homo sapiens)
Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Homo sapiens)
PEX5S,L:Cargo:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5S,L:Cargo protein [cytosol] (Homo sapiens)
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
HMGCL(1-325) [cytosol] (Homo sapiens)
PEX5S,L binds cargo proteins containing PTS1 (Homo sapiens)
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
HMGCL(1-325) [cytosol] (Homo sapiens)
PEX5S,L:Cargo protein [cytosol] (Homo sapiens)
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
HMGCL(1-325) [cytosol] (Homo sapiens)
PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Homo sapiens)
PEX5S,L:Cargo protein [cytosol] (Homo sapiens)
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
HMGCL(1-325) [cytosol] (Homo sapiens)
PEX5S,L:Cargo:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5S,L:Cargo protein [cytosol] (Homo sapiens)
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
HMGCL(1-325) [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P35914 HMGCL
Gene Names
HMGCL
Chain
transit peptide:1-27, chain:28-325
Reference Genes
BioGPS Gene:3155 HMGCL
COSMIC (genes):HMGCL HMGCL
CTD Gene:3155 HMGCL
dbSNP Gene:3155 HMGCL
ENSEMBL:ENSG00000117305 HMGCL
ENSEMBL_homo_sapiens_GENE:ENSG00000117305.15 HMGCL
HGNC:5005 HMGCL
KEGG Gene (Homo sapiens):3155 HMGCL
Monarch:3155 HMGCL
NCBI Gene:3155 HMGCL
OMIM:613898 HMGCL
UCSC:P35914 HMGCL
Reference Transcript
RefSeq:NM_000191.2 HMGCL
RefSeq:NM_001166059.1 HMGCL
Other Identifiers
11756250_s_at
16683423
202772_PM_at
202772_at
2401610
2401611
2401612
2401615
2401621
2401626
2401630
2401634
2401635
2401636
2401637
2401638
3155
38425_at
7913682
A_23_P145
GE57571
GE60540
GO:0000287
GO:0003824
GO:0004419
GO:0005198
GO:0005739
GO:0005759
GO:0005777
GO:0005782
GO:0005829
GO:0006091
GO:0006520
GO:0006552
GO:0006629
GO:0007005
GO:0016829
GO:0016833
GO:0030145
GO:0032991
GO:0043226
GO:0046872
GO:0046951
HMNXSV003022254
ILMN_2122420
L07033_at
PH_hs_0026011
TC01005330.hg
g4504426_3p_at
Participates
as a member of
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
Other forms of this molecule
HMGCL(1-325) [peroxisomal matrix]
HMGCL [mitochondrial matrix]
Inferred To
hmgcl [cytosol]
(Xenopus tropicalis)
Hmgcl [cytosol]
(Drosophila melanogaster)
HMGCL [cytosol]
(Canis familiaris)
HMGCL [cytosol]
(Sus scrofa)
HMGCL(1-325) [cytosol]
(Bos taurus)
HMGCL(1-325) [cytosol]
(Caenorhabditis elegans)
HMGCL(1-325) [cytosol]
(Gallus gallus)
HMGCL(1-325) [cytosol]
(Mus musculus)
HMGCL(1-325) [cytosol]
(Rattus norvegicus)
hmgL [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_000182.2
,
NP_001159531.1
OpenTargets
ENSG00000117305
HPA
ENSG00000117305-HMGCL
GeneCards
P35914
Ensembl
ENST00000374490
,
ENST00000436439
,
ENSP00000363614
,
ENSG00000117305
,
ENSP00000389281
PRO
P35914
Pharos - Targets
P35914
Orphanet
16207
HMDB Protein
HMDBP00009
PDB
2CW6
,
3MP3
,
3MP5
,
3MP4
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