Reactome | TRMT61B [mitochondrial matrix]

TRMT61B [mitochondrial matrix]

Stable Identifier

R-HSA-6787512

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

tRNA, TR61B_HUMAN

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External Reference Information

External Reference

UniProt:Q9BVS5 TRMT61B

Gene Names

TRMT61B

Chain

transit peptide:1-, chain:-477

Reference Genes

BioGPS Gene:55006 TRMT61B

COSMIC (genes):TRMT61B TRMT61B

CTD Gene:55006 TRMT61B

dbSNP Gene:55006 TRMT61B

ENSEMBL:ENSG00000171103 TRMT61B

ENSEMBL_homo_sapiens_GENE:ENSG00000171103.11 TRMT61B

HGNC:26070 TRMT61B

KEGG Gene (Homo sapiens):55006 TRMT61B

Monarch:55006 TRMT61B

NCBI Gene:55006 TRMT61B

OMIM:619404 TRMT61B

UCSC:Q9BVS5 TRMT61B

Reference Transcript

RefSeq:NM_017910.3 TRMT61B

Other Identifiers

11723475_a_at

11756472_x_at

16896026

221229_PM_s_at

221229_s_at

2546298

2546299

2546300

2546301

2546304

2546305

2546306

2546308

2546311

2546314

2546317

2546318

2546319

55006

55674_f_at

60068_i_at

60069_r_at

65663_at

8051226

A_23_P259823

GE55578

GO:0003824

GO:0005515

GO:0005739

GO:0005759

GO:0006399

GO:0008033

GO:0008168

GO:0016071

GO:0016429

GO:0016433

GO:0016740

GO:0030488

GO:0031167

GO:0031515

GO:0032259

GO:0042254

GO:0043226

GO:0061953

GO:0070901

GO:0080009

GO:0090646

GO:0140053

GO:0140098

GO:0160107

HMNXSV003012464

HMNXSV003012543

PH_hs_0002735

TC02001703.hg

g13435382_3p_s_at

Participates

as a component of

TRMT61B tetramer [mitochondrial matrix] (Homo sapiens)

Cross References

RefSeq

NP_060380.3

OpenTargets

ENSG00000171103

IntEnz

2.1.1.220

GeneCards

Q9BVS5

HPA

ENSG00000171103-TRMT61B

Ensembl

ENSG00000171103, ENSP00000302801, ENST00000306108

PRO

Q9BVS5

Pharos - Targets

Q9BVS5

HMDB Protein

HMDBP09048

PDB

2B25

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92985 IRF7	5	K63polyUb-IRF7 [endosome membrane] (R-HSA-975154) IRF7 [endosome membrane] (R-HSA-450274) p-S477,S479-IRF7 [nucleoplasm] (R-HSA-450270) p-S477,S479-IRF7 [cytosol] (R-HSA-450318) IRF7 [cytosol] (R-HSA-450281)	0.623	3
UniProt:Q5TEU4 NDUFAF5	1	NDUFAF5 [mitochondrial inner membrane] (R-HSA-5689127)	0.615	4
UniProt:Q9HA77 CARS2	1	CARS2(1-?) [mitochondrial matrix] (R-HSA-379632)	0.615	3
UniProt:P13196 ALAS1	2	PXLP-ALAS1 [mitochondrial matrix] (R-HSA-1022086) ALAS1 [mitochondrial matrix] (R-HSA-189438)	0.615	3
UniProt:P46199 MTIF2	1	MTIF2 [mitochondrial matrix] (R-HSA-5368271)	0.615	4
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q53FT3 HIKESHI	2	Hikeshi [cytosol] (R-HSA-5216031) Hikeshi [nucleoplasm] (R-HSA-5252048)	0.527	2
UniProt:Q4G176 ACSF3	1	ACSF3 [mitochondrial matrix] (R-HSA-5696011)	0.527	2
UniProt:P11182 DBT	11	DBT [cytosol] (R-HSA-9714663) I98M Lipo-K105-DBT [mitochondrial matrix] (R-HSA-9865057) Lipo-K105-DBT [mitochondrial matrix] (R-HSA-70017) Isobutyryl-lipoH2-K105-DBT [mitochondrial matrix] (R-HSA-9859151) Isovaleryl-lipoH2-K105-DBT [mitochondrial matrix] (R-HSA-9859144) 2-Methylbutyryl-lipoH2-K105-DBT [mitochondrial matrix] (R-HSA-9859145) LipoH2-K105-DBT [mitochondrial matrix] (R-HSA-9859167) DBT [mitochondrial matrix] (R-HSA-6792584) P276C Lipo-K105-DBT [mitochondrial matrix] (R-HSA-9865046) S399C Lipo-K105-DBT [mitochondrial matrix] (R-HSA-9865036) K313_Y338del Lipo-K105-DBT [mitochondrial matrix] (R-HSA-9865051)	0.527	2
UniProt:Q9HC36 MRM3	1	RNMTL1 [mitochondrial matrix] (R-HSA-6793067)	0.483	2
UniProt:Q5U5X0 LYRM7	1	LYRM7 [mitochondrial matrix] (R-HSA-9866252)	0.483	2

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