Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix]

Stable Identifier
R-HSA-9837979
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
mitochondrial inner membrane, mitochondrial matrix
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Literature References
PubMed ID Title Journal Year
36629048 LONP1 targets HMGCS2 to protect mitochondrial function and attenuate chronic kidney disease

Bai, M, Wu, M, Jiang, M, He, J, Deng, X, Xu, S, Fan, J, Miao, M, Wang, T, Li, Y, Yu, X, Wang, L, Zhang, Y, Huang, S, Yang, L, Jia, Z, Zhang, A

EMBO Mol Med 2023
12198491 Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism

Bota, DA, Davies, KJ

Nat Cell Biol 2002
33637676 LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival

Lee, YG, Kim, HW, Nam, Y, Shin, KJ, Lee, YJ, Park, DH, Rhee, HW, Seo, JK, Chae, YC

Oncogenesis 2021
23201127 Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease

Lu, B, Lee, J, Nie, X, Li, M, Morozov, YI, Venkatesh, S, Bogenhagen, DF, Temiakov, D, Suzuki, CK

Mol Cell 2013
15870080 Cleavage site selection within a folded substrate by the ATP-dependent lon protease

Ondrovicová, G, Liu, T, Singh, K, Tian, B, Li, H, Gakh, O, Perecko, D, Janata, J, Granot, Z, Orly, J, Kutejova, E, Suzuki, CK

J Biol Chem 2005
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Inferred To
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Bos taurus)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Caenorhabditis elegans)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Canis familiaris)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Danio rerio)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Dictyostelium discoideum)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Drosophila melanogaster)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Gallus gallus)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Mus musculus)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Rattus norvegicus)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Saccharomyces cerevisiae)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Schizosaccharomyces pombe)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Sus scrofa)
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