Reactome | STX5 [cytosol]

STX5 [cytosol]

Stable Identifier

R-HSA-9613991

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Syntaxin-5, STX5_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q13190 STX5

Gene Names

STX5, STX5A

Chain

chain:1-355

Reference Genes

BioGPS Gene:6811 STX5

COSMIC (genes):STX5 STX5

CTD Gene:6811 STX5

dbSNP Gene:6811 STX5

ENSEMBL:ENSG00000162236 STX5

ENSEMBL:ENSG00000162236.13 STX5

HGNC:11440 STX5

KEGG Gene (Homo sapiens):6811 STX5

Monarch:6811 STX5

NCBI Gene:6811 STX5

OMIM:603189 STX5

UCSC:Q13190 STX5

Reference Transcript

Other Identifiers

11717259_a_at

11748552_a_at

16739588

203330_PM_s_at

203330_s_at

3376194

3376195

3376196

3376206

3376208

3376210

3376212

3376213

3376215

3376216

3376217

3376222

3376223

3376226

40068_at

6811

7948864

A_23_P24755

GE79529

GO:0000139

GO:0000149

GO:0005484

GO:0005515

GO:0005783

GO:0005789

GO:0005794

GO:0005829

GO:0006886

GO:0006888

GO:0006906

GO:0012505

GO:0012507

GO:0016020

GO:0016192

GO:0030163

GO:0031201

GO:0031410

GO:0031982

GO:0033116

GO:0034498

GO:0042147

GO:0043226

GO:0045296

GO:0045732

GO:0048278

GO:0048280

GO:0060090

GO:0061024

GO:0090166

GO:1903358

HMNXSV003012758

ILMN_1749345

ILMN_1777444

ILMN_1808860

PH_hs_0019737

TC11001881.hg

U26648_at

g4507292_3p_s_at

Participates

as a member of

Tail-anchored proteins [cytosol] (Homo sapiens)

Other forms of this molecule

STX5 [endoplasmic reticulum membrane]

STX5 [ER to Golgi transport vesicle membrane]

STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane]

STX5 [Golgi membrane]

Inferred To

sed5 [cytosol] (Schizosaccharomyces pombe)

SED5 [cytosol] (Saccharomyces cerevisiae)

Stx5 [cytosol] (Mus musculus)

Stx5 [cytosol] (Rattus norvegicus)

wu:fj81f08 [cytosol] (Danio rerio)

STX5 [cytosol] (Bos taurus)

STX5 [cytosol] (Canis familiaris)

STX5 [cytosol] (Gallus gallus)

STX5 [cytosol] (Plasmodium falciparum)

stx5 [cytosol] (Xenopus tropicalis)

syx-5 [cytosol] (Caenorhabditis elegans)

Syx5 [cytosol] (Drosophila melanogaster)

syn5 [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001317223.1, NP_003155.2, NP_001231595.1

OpenTargets

ENSG00000162236

HPA

ENSG00000162236-STX5

GeneCards

Q13190

Ensembl

ENSP00000294179, ENSG00000162236, ENSP00000367129, ENST00000377897, ENSP00000378182, ENST00000394690, ENST00000294179

PRO

Q13190

Pharos - Targets

Q13190

PDB

3EFO

Interactors (33)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12846 STX4	4	STX4 [plasma membrane] (R-HSA-181519) STX4 [phagocytic vesicle membrane] (R-HSA-2029044) STX4 [cytosol] (R-HSA-114505) p-STX4 [cytosol] (R-HSA-114681)	0.718	6
UniProt:P61764 STXBP1	2	STXBP1 [cytosol] (R-HSA-6794256) STXBP1 [plasma membrane] (R-HSA-2980862)	0.718	6
UniProt:Q8N6L0 KASH5			0.718	6
UniProt:Q9H115 NAPB	1	NAPB [cytosol] (R-HSA-5688553)	0.718	9
UniProt:O95183 VAMP5			0.666	4
UniProt:P38932 VPS45			0.556	3
IntAct:EBI-22326698 CCSB ORF ID			0.556	3
UniProt:Q4LEZ3 AARD			0.556	3
UniProt:O75410 TACC1			0.556	3
UniProt:P43360 MAGA6			0.556	3
UniProt:Q8TDT2 GP152			0.556	3
UniProt:Q06481-5 APLP2			0.556	3
UniProt:Q13277 STX3	1	STX3 [plasma membrane] (R-HSA-449131)	0.556	3
UniProt:P32856-2 STX2			0.556	3
UniProt:Q494R4-2 CCDC153			0.556	3
UniProt:Q68CJ9 CREB3L3	10	CREB3L3(1-?) [nucleoplasm] (R-HSA-6784629) CREB3L3(1-?) [cytosol] (R-HSA-6784654) CREB3L3 [endoplasmic reticulum membrane] (R-HSA-6784669) CREB3L3(?-461) [endoplasmic reticulum membrane] (R-HSA-6784710) CREB3L3 [Golgi membrane] (R-HSA-8874144) CREB3L3(365-461) [Golgi membrane] (R-HSA-8874130) CREB3L3(1-364) [Golgi membrane] (R-HSA-8874158) CREB3L3(1-323) [cytosol] (R-HSA-8874214) CREB3L3(1-323) [nucleoplasm] (R-HSA-8874217) CREB3L3(324-364) [Golgi membrane] (R-HSA-8874183)	0.556	3
UniProt:O95872 GPAN1			0.556	3
UniProt:Q9BUF7-2 CRB3			0.556	3
UniProt:Q9H6H4 REEP4			0.556	3
UniProt:Q5JX71 F209A			0.556	3
UniProt:Q9UNK0 STX8			0.556	3
UniProt:Q8N5M9 JAGN1			0.556	3
UniProt:Q86WV6 STING1	5	TMEM173 [plasma membrane] (R-HSA-6804815) TMEM173 [secretory granule membrane] (R-HSA-6804798) K63polyUb-STING [endoplasmic reticulum membrane] (R-HSA-3134805) K63polyUb-STING [cytoplasmic vesicle membrane] (R-HSA-3248021) STING [endoplasmic reticulum membrane] (R-HSA-1834940)	0.556	3
UniProt:Q86VR2 RETR3			0.556	3
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.556	3
UniProt:Q9HCJ2 LRC4C			0.556	3
UniProt:Q9ULD2-3 MTUS1			0.556	3
UniProt:Q7Z5P4 HSD17B13	1	HSD17B13 [cytosol] (R-HSA-8862029)	0.556	3
UniProt:Q8NBQ5 HSD17B11	1	HSD17B11 [cytosol] (R-HSA-5693370)	0.556	3
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:O14653 GOSR2	4	GOSR2 [endoplasmic reticulum membrane] (R-HSA-5689451) GOSR2 [ER to Golgi transport vesicle membrane] (R-HSA-5689800) GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-535472) GOSR2 [Golgi membrane] (R-HSA-6807755)	0.556	3
UniProt:Q16623 STX1A	5	STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.556	3
UniProt:P54920 NAPA	1	NAPA [cytosol] (R-HSA-264469)	0.547	2

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