Reactome | NAPA [cytosol]

NAPA [cytosol]

Stable Identifier

R-HSA-264469

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Alpha-soluble NSF attachment protein, SNAA_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P54920 NAPA

Gene Names

NAPA, SNAPA

Chain

chain:1-295

Reference Genes

BioGPS Gene:8775 NAPA

COSMIC (genes):NAPA NAPA

CTD Gene:8775 NAPA

dbSNP Gene:8775 NAPA

ENSEMBL:ENSG00000105402 NAPA

ENSEMBL:ENSG00000105402.8 NAPA

HGNC:7641 NAPA

KEGG Gene (Homo sapiens):8775 NAPA

Monarch:8775 NAPA

NCBI Gene:8775 NAPA

OMIM:603215 NAPA

UCSC:P54920 NAPA

Reference Transcript

RefSeq:NM_003827.3 NAPA

Other Identifiers

11744101_s_at

11744824_a_at

11745116_a_at

11745117_x_at

16873751

206491_PM_s_at

206491_s_at

208751_PM_at

208751_at

36977_at

3866606

3866607

3866608

3866609

3866611

3866612

3866615

3866618

3866620

3866625

3866626

3866634

3866638

3866645

3866646

3866647

8037913

8775

A_23_P55990

GE59128

GO:0000149

GO:0005483

GO:0005515

GO:0005576

GO:0005615

GO:0005829

GO:0005886

GO:0006886

GO:0006891

GO:0007420

GO:0010807

GO:0015031

GO:0016020

GO:0016082

GO:0016192

GO:0019905

GO:0023052

GO:0030154

GO:0030182

GO:0035249

GO:0035494

GO:0043226

GO:0044877

GO:0045176

GO:0048856

GO:0060090

GO:0061024

GO:0061025

GO:0065003

GO:0070044

GO:0070062

GO:0098793

GO:0098978

HMNXSV003009256

ILMN_1713285

PH_hs_0031325

TC19001666.hg

TC19002531.hg

U39412_at

g12654654_3p_a_at

Participates

as a component of

BLOC-1 Complex [lysosomal membrane] (Homo sapiens)

as an input of

Formation Of Bloc-1 Complex (Homo sapiens)

as a member of

SNAPs [cytosol] (Homo sapiens)

Inferred To

snap-1 [cytosol] (Caenorhabditis elegans)

alphaSnap [cytosol] (Drosophila melanogaster)

snpA [cytosol] (Dictyostelium discoideum)

napa [cytosol] (Xenopus tropicalis)

NAPA [cytosol] (Bos taurus)

NAPA [cytosol] (Canis familiaris)

NAPA [cytosol] (Danio rerio)

NAPA [cytosol] (Gallus gallus)

NAPA [cytosol] (Plasmodium falciparum)

NAPA [cytosol] (Sus scrofa)

SEC17 [cytosol] (Saccharomyces cerevisiae)

Napa [cytosol] (Mus musculus)

Napa [cytosol] (Rattus norvegicus)

sec17 [cytosol] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_003818.2

OpenTargets

ENSG00000105402

HPA

ENSG00000105402-NAPA

GeneCards

P54920

Ensembl

ENSP00000263354, ENST00000263354, ENSG00000105402

PRO

P54920

Pharos - Targets

P54920

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P46459 NSF	1	NSF [cytosol] (R-HSA-264471)	0.669	3
UniProt:O00161 SNAP23	5	SNAP23 [phagocytic vesicle membrane] (R-HSA-8863966) p-S95-SNAP23 [phagocytic vesicle membrane] (R-HSA-8863923) SNAP23 [tertiary granule membrane] (R-HSA-6806141) SNAP23 [plasma membrane] (R-HSA-376345) SNAP23 [specific granule membrane] (R-HSA-6806157)	0.632	3
UniProt:Q12846 STX4	4	STX4 [plasma membrane] (R-HSA-181519) STX4 [phagocytic vesicle membrane] (R-HSA-2029044) STX4 [cytosol] (R-HSA-114505) p-STX4 [cytosol] (R-HSA-114681)	0.632	3
UniProt:O15155 BET1	3	BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688142) BET1 [transport vesicle] (R-HSA-6808719) BET1 [Golgi membrane] (R-HSA-6807743)	0.569	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q13190 STX5	5	STX5 [endoplasmic reticulum membrane] (R-HSA-5689474) STX5 [ER to Golgi transport vesicle membrane] (R-HSA-5689838) STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688157) STX5 [Golgi membrane] (R-HSA-6807771) STX5 [cytosol] (R-HSA-9613991)	0.547	2
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.527	2
UniProt:Q6NUQ1 RINT1	1	RINT1 [cytosol] (R-HSA-6810991)	0.527	2
UniProt:Q99747 NAPG	1	NAPG [cytosol] (R-HSA-5688555)	0.527	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P0DTD8 NS7B			0.527	2
UniProt:Q9UEU0 VTI1B	2	VTI1B [extracellular region] (R-HSA-8862983) VTI1B [platelet alpha granule lumen] (R-HSA-8862964)	0.527	2