Reactome | PRPF19 [nucleoplasm]

PRPF19 [nucleoplasm]

Stable Identifier

R-HSA-5420907

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Pre-mRNA-processing factor 19, PRP19_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UMS4 PRPF19

Gene Names

PRPF19, NMP200, PRP19, SNEV

Chain

initiator methionine:, chain:2-504

Reference Genes

BioGPS Gene:27339 PRPF19

COSMIC (genes):PRPF19 PRPF19

CTD Gene:27339 PRPF19

dbSNP Gene:27339 PRPF19

ENSEMBL:ENSG00000110107 PRPF19

ENSEMBL_homo_sapiens_GENE:ENSG00000110107.9 PRPF19

HGNC:17896 PRPF19

KEGG Gene (Homo sapiens):27339 PRPF19

Monarch:27339 PRPF19

NCBI Gene:27339 PRPF19

OMIM:608330 PRPF19

UCSC:Q9UMS4 PRPF19

Reference Transcript

RefSeq:NM_014502.4 PRPF19

Other Identifiers

11716736_at

16738869

203103_PM_s_at

203103_s_at

27339

33230_at

3375050

3375051

3375052

3375053

3375055

3375056

3375058

3375059

3375060

3375061

3375062

3375063

3375064

3375065

3375066

3375067

3375069

3375070

3375071

3375075

7948476

A_33_P3363012

GE55215

GE88487

GO:0000077

GO:0000209

GO:0000228

GO:0000244

GO:0000245

GO:0000398

GO:0000974

GO:0003824

GO:0004842

GO:0005515

GO:0005634

GO:0005654

GO:0005662

GO:0005681

GO:0005694

GO:0005737

GO:0005811

GO:0005819

GO:0005856

GO:0006281

GO:0006303

GO:0006397

GO:0006629

GO:0006974

GO:0008104

GO:0008380

GO:0008610

GO:0010498

GO:0016020

GO:0016071

GO:0016567

GO:0016607

GO:0016740

GO:0023052

GO:0030163

GO:0034450

GO:0035861

GO:0036211

GO:0042802

GO:0043226

GO:0048026

GO:0061630

GO:0065003

GO:0070534

GO:0071006

GO:0071007

GO:0071013

GO:0140096

HMNXSV003015621

ILMN_1769545

PH_hs_0010429

TC11001844.hg

TC11003169.hg

g7657380_3p_a_at

Participates

as a component of

Inferred To

prp-19 [nucleoplasm] (Caenorhabditis elegans)

PRP19 [nucleoplasm] (Saccharomyces cerevisiae)

prp19 [nucleoplasm] (Dictyostelium discoideum)

prp19 [nucleoplasm] (Schizosaccharomyces pombe)

PRPF19 [nucleoplasm] (Bos taurus)

PRPF19 [nucleoplasm] (Canis familiaris)

PRPF19 [nucleoplasm] (Gallus gallus)

PRPF19 [nucleoplasm] (Plasmodium falciparum)

PRPF19 [nucleoplasm] (Sus scrofa)

prpf19 [nucleoplasm] (Danio rerio)

prpf19 [nucleoplasm] (Xenopus tropicalis)

Prp19 [nucleoplasm] (Drosophila melanogaster)

Prpf19 [nucleoplasm] (Mus musculus)

Prpf19 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_055317.1

OpenTargets

ENSG00000110107

HPA

ENSG00000110107-PRPF19

GeneCards

Q9UMS4

Ensembl

ENST00000227524, ENSG00000110107, ENSP00000227524

PRO

Q9UMS4

Pharos - Targets

Q9UMS4

PDB

6ICZ, 6ID1, 5MQF, 6ID0, 5XJC, 4LG8, 7W5B, 7W5A, 6FF7, 8CH6, 8C6J, 6QDV, 5Z56, 5YZG, 5Z57, 7A5P, 7W59

HMDB Protein

HMDBP09278

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P52756 RBM5	1	RBM5 [nucleoplasm] (R-HSA-72049)	0.736	8
UniProt:O60508 CDC40	1	CDC40 [nucleoplasm] (R-HSA-72062)	0.716	5
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.643	4
UniProt:Q8WUD4 CCDC12	1	CCDC12 [nucleoplasm] (R-HSA-9769561)	0.643	4
UniProt:Q9CSN1 Snw1	1	Snw1 [nucleoplasm] (R-MMU-2065315)	0.564	2
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.527	3
UniProt:O95926 SYF2	1	SYF2 [nucleoplasm] (R-HSA-8867884)	0.527	3
UniProt:O43815 STRN	5	STRN [cytosol] (R-HSA-9037081) STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673902) p-11Y-STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673908) STRN(1-137)-ALK(1058-1620) fusion [cytosol] (R-HSA-9700485) STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9700467)	0.527	2
UniProt:Q2TBE0 CWF19L2	1	CWF19L2 [nucleoplasm] (R-HSA-9770846)	0.527	3
UniProt:Q9BW85 YJU2	1	YJU2 [nucleoplasm] (R-HSA-9770430)	0.527	2
UniProt:Q9H5Z1 DHX35	1	DHX35 [nucleoplasm] (R-HSA-9770427)	0.527	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.527	3
UniProt:Q9BRR8 GPATCH1	1	GPATCH1 [nucleoplasm] (R-HSA-9770419)	0.527	3
UniProt:P16383 GCFC2	1	GCFC2 [nucleoplasm] (R-HSA-8869311)	0.527	3

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