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CCDC12 [nucleoplasm]
Stable Identifier
R-HSA-9769561
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Coiled-coil domain-containing protein 12, CCD12_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
CCDC12 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
CCDC12 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
CCDC12 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
CCDC12 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C* complex (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
CCDC12 [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
CCDC12 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
CCDC12 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
CCDC12 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
CCDC12 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
CCDC12 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WUD4 CCDC12
Gene Names
CCDC12
Chain
chain:1-166
Reference Genes
BioGPS Gene:151903 CCDC12
COSMIC (genes):CCDC12 CCDC12
CTD Gene:151903 CCDC12
dbSNP Gene:151903 CCDC12
ENSEMBL:ENSG00000160799 CCDC12
ENSEMBL_homo_sapiens_GENE:ENSG00000160799.12 CCDC12
HGNC:28332 CCDC12
KEGG Gene (Homo sapiens):151903 CCDC12
Monarch:151903 CCDC12
NCBI Gene:151903 CCDC12
UCSC:Q8WUD4 CCDC12
Reference Transcript
RefSeq:NM_001277074.1 CCDC12
Other Identifiers
11718596_a_at
151903
16953035
226011_PM_at
226011_at
2672472
2672473
2672474
2672475
2672477
2672479
2672490
2672505
2672506
2672507
52092_at
8086698
A_23_P372334
GO:0005515
GO:0005634
GO:0005654
GO:0005684
GO:0043226
GO:0071014
HMNXSV003038883
HMNXSV003051879
Hs.43773.0.S1_3p_at
ILMN_1725071
PH_hs_0030144
TC03001363.hg
Participates
as a component of
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
as an input of
Formation of the Spliceosomal Bact complex (Homo sapiens)
as an output of
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
Inferred To
CCDC12 [nucleoplasm]
(Bos taurus)
CCDC12 [nucleoplasm]
(Canis familiaris)
CCDC12 [nucleoplasm]
(Dictyostelium discoideum)
CCDC12 [nucleoplasm]
(Gallus gallus)
CCDC12 [nucleoplasm]
(Plasmodium falciparum)
CCDC12 [nucleoplasm]
(Sus scrofa)
ccdc12 [nucleoplasm]
(Danio rerio)
ccdc12 [nucleoplasm]
(Xenopus tropicalis)
Ccdc12 [nucleoplasm]
(Mus musculus)
Ccdc12 [nucleoplasm]
(Rattus norvegicus)
Dmel\CG15525 [nucleoplasm]
(Drosophila melanogaster)
cwf18 [nucleoplasm]
(Schizosaccharomyces pombe)
ccdc-12 [nucleoplasm]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001264003.1
OpenTargets
ENSG00000160799
HPA
ENSG00000160799-CCDC12
GeneCards
Q8WUD4
Ensembl
ENSP00000416263
,
ENSP00000508011
,
ENSG00000160799
,
ENST00000425441
,
ENST00000683445
PRO
Q8WUD4
Pharos - Targets
Q8WUD4
Interactors (21)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H1Y0 ATG5
3
ATG5 [phagocytic vesicle membrane]
(R-HSA-5205636)
GlyK130-ATG5 [cytosol]
(R-HSA-5683582)
ATG5 [cytosol]
(R-HSA-936010)
0.742
7
UniProt:Q9UMS4 PRPF19
1
PRPF19 [nucleoplasm]
(R-HSA-5420907)
0.643
4
UniProt:Q9BZJ0 CRNKL1
1
CRNKL1 [nucleoplasm]
(R-HSA-8867899)
0.632
4
UniProt:Q9CSN1 Snw1
1
Snw1 [nucleoplasm]
(R-MMU-2065315)
0.564
2
UniProt:P09661 SNRPA1
1
SNRPA1 [nucleoplasm]
(R-HSA-71958)
0.527
4
UniProt:P62304 SNRPE
2
SNRPE [nucleoplasm]
(R-HSA-71905)
SNRPE [cytosol]
(R-HSA-191782)
0.527
4
UniProt:Q8TAD8 SNIP1
1
SNIP1 [nucleoplasm]
(R-HSA-3222315)
0.527
2
UniProt:Q86SE5 RALYL
0.527
2
UniProt:Q96DI7 SNRNP40
1
SNRNP40 [nucleoplasm]
(R-HSA-71877)
0.527
2
UniProt:Q9BQ65 USB1
0.527
2
UniProt:Q9BRX9 WDR83
1
WDR83 [endosome membrane]
(R-HSA-5672942)
0.527
4
UniProt:P63162 SNRPN
1
Me2-R108,R112-SNRPN [nucleoplasm]
(R-HSA-8865931)
0.527
3
UniProt:Q9BW85 YJU2
1
YJU2 [nucleoplasm]
(R-HSA-9770430)
0.527
2
UniProt:Q9BRK4 LZTS2
0.527
2
UniProt:O95926 SYF2
1
SYF2 [nucleoplasm]
(R-HSA-8867884)
0.527
3
UniProt:Q96FV0 LRC46
0.527
2
UniProt:Q92997 DVL3
4
pp-DVL3 [cytosol]
(R-HSA-3772400)
p-DVL3 [cytosol]
(R-HSA-201680)
DVL3 [cytosol]
(R-HSA-201678)
ub-DVL3 [cytosol]
(R-HSA-4652688)
0.527
2
UniProt:Q14562 DHX8
1
DHX8 [nucleoplasm]
(R-HSA-5688092)
0.527
3
UniProt:Q96AT1 K1143
0.527
2
UniProt:O75152 ZC3H11A
1
ZC3H11A [nucleoplasm]
(R-HSA-8850659)
0.483
2
UniProt:Q16629 SRSF7
1
SRSF7 [nucleoplasm]
(R-HSA-72029)
0.483
2
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