Reactome | PRPF19 [nucleoplasm]

PRPF19 [nucleoplasm]

Stable Identifier

R-PFA-5420907

Type

Protein [EntityWithAccessionedSequence]

Species

Plasmodium falciparum

Compartment

nucleoplasm

Synonyms

O77325

Locations in the PathwayBrowser

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DNA Repair (Plasmodium falciparum)

- Nucleotide Excision Repair (Plasmodium falciparum)
  - Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Plasmodium falciparum)
    - Dual incision in TC-NER (Plasmodium falciparum)
      - 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Plasmodium falciparum)
        
        TC-NER incision complex [nucleoplasm] (Plasmodium falciparum)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Plasmodium falciparum)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Plasmodium falciparum)
        
        XAB2 complex [nucleoplasm] (Plasmodium falciparum)
        
        PRPF19 [nucleoplasm] (Plasmodium falciparum)
        
        TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Plasmodium falciparum)
        
        XAB2 complex [nucleoplasm] (Plasmodium falciparum)
        
        PRPF19 [nucleoplasm] (Plasmodium falciparum)
      - DNA polymerases delta, epsilon or kappa bind the TC-NER site (Plasmodium falciparum)
        
        TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Plasmodium falciparum)
        
        XAB2 complex [nucleoplasm] (Plasmodium falciparum)
        
        PRPF19 [nucleoplasm] (Plasmodium falciparum)
        
        TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Plasmodium falciparum)
        
        XAB2 complex [nucleoplasm] (Plasmodium falciparum)
        
        PRPF19 [nucleoplasm] (Plasmodium falciparum)
    - Gap-filling DNA repair synthesis and ligation in TC-NER (Plasmodium falciparum)
      - Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Plasmodium falciparum)
        
        TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Plasmodium falciparum)
        
        XAB2 complex [nucleoplasm] (Plasmodium falciparum)
        
        PRPF19 [nucleoplasm] (Plasmodium falciparum)
        
        TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Plasmodium falciparum)
        
        XAB2 complex [nucleoplasm] (Plasmodium falciparum)
        
        PRPF19 [nucleoplasm] (Plasmodium falciparum)

External Reference Information

External Reference

UniProt:O77325

Reference Genes

BioGPS Gene:814402

ENSEMBL:PF3D7_0308600

KEGG Gene (Plasmodium falciparum):PF3D7_0308600

Monarch:814402

NCBI Gene:814402

PlasmoDB:PF3D7_0308600

Reference Transcript

RefSeq:XM_001351124.1

Participates

as a component of

Inferred From

PRPF19 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_001351160.1

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