STRN(1-265)-PDGFRA(580-1089) fusion [cytosol]

Stable Identifier
R-HSA-9673902
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
17555450 Two novel imatinib-responsive PDGFRA fusion genes in chronic eosinophilic leukaemia

Grand, FH, Clark, A, Curtis, CE, Reiter, A, Minervini, MM, Cross, NC, Perla, G, Musto, P, Murphy, J, Stewart, J

Br. J. Haematol. 2007
External Reference Information
External Reference
UniProt:O43815 STRN
Gene Names
STRN
Chain
chain:1-780
Reference Genes
BioGPS Gene:6801 STRN
COSMIC (genes):STRN STRN
CTD Gene:6801 STRN
dbSNP Gene:6801 STRN
ENSEMBL:ENSG00000115808 STRN
HGNC:11424 STRN
KEGG Gene (Homo sapiens):6801 STRN
Monarch:6801 STRN
NCBI Gene:6801 STRN
OMIM:614765 STRN
UCSC:O43815 STRN
Reference Transcript
Other Identifiers
0004570278
11730500_at
11755875_a_at
16896374
205520_at
215287_at
227422_at
230734_x_at
236388_at
236980_at
242989_at
244354_at
2548253
2548254
2548256
2548257
2548258
2548260
2548262
2548263
2548265
2548266
2548268
2548270
2548271
2548273
2548275
2548276
2548277
2548279
2548281
2548282
2548283
2548285
2548286
2548289
2548291
2548292
2548296
2548299
2548301
2548302
2548303
2548304
2548305
2548317
2548318
2548319
2804784
31736_at
33298_at
4032637
53132_at
60565_at
62989_f_at
62990_r_at
62991_f_at
6801
70775_at
78779_at
8051443
81992_at
82977_at
A_19_P00316199
A_19_P00316200
A_19_P00322614
A_19_P00808033
A_23_P165521
A_32_P174398
A_32_P78904
A_32_P92536
GE81242
GE872109
GO:0003674
GO:0005515
GO:0005516
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0005886
GO:0005923
GO:0007165
GO:0007267
GO:0007626
GO:0008134
GO:0008150
GO:0008283
GO:0008285
GO:0014069
GO:0016020
GO:0016055
GO:0016358
GO:0019899
GO:0022607
GO:0030054
GO:0030154
GO:0030331
GO:0030425
GO:0032991
GO:0034330
GO:0042995
GO:0043025
GO:0043197
GO:0043226
GO:0044877
GO:0045202
GO:0045211
GO:0048856
GO:0051721
GO:0051897
GO:0070016
GO:0070830
GO:0090443
HMNXSV003019811
Hs.127486.0.A1_3p_at
Hs.128434.0.S1_3p_at
Hs.135162.0.A1_3p_at
Hs.211253.0.A1_3p_at
Hs.46667.0.A1_3p_at
Hs.5635.0.A1_3p_at
Hs.90787.0.A1_3p_at
ILMN_1749882
ILMN_2129273
PH_hs_0007315
PH_hs_0033959
TC02001736.hg
TC02004160.hg
g4507282_3p_at
Participates
as a component of
as a candidate of
Other forms of this molecule
STRN [cytosol]
p-11Y STRN(1-265)-PDGFRA(580-1089) fusion [cytosol]
STRN(1-137)-ALK(1058-1620) fusion [cytosol]
STRN(1-137)-p-7Y ALK(1058-1620) fusion [cytosol]
Modified Residues
Name
Insertion of residues 580 to 1089 at 266 from UniProt:P16234 PDGFRA
Coordinate
266
Disease
Name Identifier Synonyms
hypereosinophilic syndrome DOID:999 Eosinophilic leukocytosis, eosinophilia
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
Interactors (32)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P30153 PPP2R1A  2 0.805 8
 UniProt:Q13033 STRN3      0.797 9
 UniProt:Q9Y6E0 STK24  4 0.784 5
 UniProt:Q9P289 STK26  3 0.773 5
 UniProt:O00506 STK25      0.773 5
 UniProt:Q9BUL8 PDC10      0.773 5
 UniProt:Q9P2B4 CT2NL      0.763 6
 UniProt:Q9Y3A3 PHOCN      0.737 5
 UniProt:P67775 PPP2CA  4 0.737 5
 UniProt:Q5VSL9 STRP1      0.708 4
 UniProt:Q9BRV8 SIKE1  1 0.643 4
 UniProt:P62714 PPP2CB  4 0.643 3
 UniProt:Q9NRL3 STRN4      0.643 3
 UniProt:P30154 PPP2R1B  2 0.643 3
 UniProt:Q14BN4 SLMAP      0.615 4
 UniProt:Q6NUQ1 RINT1  1 0.556 3
 UniProt:Q9UBB9 TFIP11  1 0.556 3
 UniProt:P78371 CCT2  3 0.527 2
 UniProt:Q8WZ74 CTTB2      0.527 2
 UniProt:Q9NVK5 FGFR1OP2  2 0.527 3
 UniProt:Q99832 CCT7  1 0.527 2
 UniProt:P49368 CCT3  1 0.527 2
 UniProt:P50990 CCT8  5 0.527 2
 UniProt:P50991 CCT4  1 0.527 2
 UniProt:P40227 CCT6A  1 0.527 2
 UniProt:P48643 CCT5  1 0.527 2
 UniProt:Q9ULQ0 STRP2      0.527 2
 UniProt:P17987 TCP1  1 0.527 2
 UniProt:Q9H2K2 TNKS2  1 0.525 2
 UniProt:Q9Y228 T3JAM      0.499 2
 UniProt:Q13188 STK3  4 0.483 3
 UniProt:Q13043 STK4  4 0.483 3
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