Reactome | MAPKAPK5 [nucleoplasm]

Stable Identifier

R-HSA-2562517

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

PRAK, MAP kinase-activated protein kinase 5, p38-regulated/activated protein kinase

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External Reference Information

External Reference

UniProt:Q8IW41 MAPKAPK5

Gene Names

MAPKAPK5, PRAK

Chain

chain:1-473

Reference Genes

COSMIC (genes):MAPKAPK5 MAPKAPK5

dbSNP Gene:8550 MAPKAPK5

ENSEMBL:ENSG00000089022 MAPKAPK5

Participates

as an output of

as an input of

as a component of

Other forms of this molecule

p-T182 MAPKAPK5 [cytosol]

p-S115 MAPKAPK5 [cytosol]

p-S115 MAPKAPK5 [nucleoplasm]

p-T182-MAPKAPK5 [nucleoplasm]

Inferred To

MAPKAPK5 [nucleoplasm] (Bos taurus)

MAPKAPK5 [nucleoplasm] (Gallus gallus)

MAPKAPK5 [nucleoplasm] (Mus musculus)

MAPKAPK5 [nucleoplasm] (Plasmodium falciparum)

MAPKAPK5 [nucleoplasm] (Sus scrofa)

mapkapk5 [nucleoplasm] (Danio rerio)

Mapkapk5 [nucleoplasm] (Rattus norvegicus)

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q16659 MAPK6 gene	6	p-3S,T MAPK6 [nucleoplasm] (R-HSA-5692665) MAPK6 [nucleoplasm] (R-HSA-5692686) p-S189 MAPK6 [nucleoplasm] (R-HSA-5687015) p-S189 MAPK6 [cytosol] (R-HSA-5687019) MAPK6 [cytosol] (R-HSA-5686979) ub-MAPK6 [cytosol] (R-HSA-5687000)	0.917	12
UniProt:Q15109 AGER	1	AGER [plasma membrane] (R-HSA-197639)	0.655	6
UniProt:P31152 MAPK4	4	MAPK4 [nucleoplasm] (R-HSA-5686975) MAPK4 [cytosol] (R-HSA-5686973) p-S186 MAPK4 [cytosol] (R-HSA-5687023) p-S186 MAPK4 [nucleoplasm] (R-HSA-5687022)	0.643	5

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