Synthesis of IP2, IP, and Ins in the cytosol

Stable Identifier
R-HSA-1855183
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Synthesis of IP2, IP, and Ins in the cytosol
Click the image above or here to open this pathway in the Pathway Browser

Inositol phosphates IP2, IP and the six-carbon cyclic alcohol inositol (Ins) are produced by various phosphatases and the inositol-3-phosphate synthase 1 (ISYNA1) (Ju et al. 2004, Ohnishi et al. 2007, Irvine & Schell 2001, Bunney & Katan 2010).

Literature References
PubMed ID Title Journal Year
17068342 Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1

Ohnishi, T, Ohba, H, Seo, KC, Im, J, Sato, Y, Iwayama, Y, Furuichi, T, Chung, SK, Yoshikawa, T

J Biol Chem 2007
15024000 Human 1-D-myo-inositol-3-phosphate synthase is functional in yeast

Ju, S, Shaltiel, G, Shamir, A, Agam, G, Greenberg, ML

J Biol Chem 2004
11331907 Back in the water: the return of the inositol phosphates

Irvine, RF, Schell, MJ

Nat Rev Mol Cell Biol 2001
20414202 Phosphoinositide signalling in cancer: beyond PI3K and PTEN

Bunney, TD, Katan, M

Nat Rev Cancer 2010
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
inositol phosphate metabolic process (0043647)
Orthologous Events
Synthesis of IP2, IP, and Ins in the cytosol (Bos taurus)
Synthesis of IP2, IP, and Ins in the cytosol (Caenorhabditis elegans)
Synthesis of IP2, IP, and Ins in the cytosol (Canis familiaris)
Synthesis of IP2, IP, and Ins in the cytosol (Danio rerio)
Synthesis of IP2, IP, and Ins in the cytosol (Dictyostelium discoideum)
Synthesis of IP2, IP, and Ins in the cytosol (Drosophila melanogaster)
Synthesis of IP2, IP, and Ins in the cytosol (Gallus gallus)
Synthesis of IP2, IP, and Ins in the cytosol (Mus musculus)
Synthesis of IP2, IP, and Ins in the cytosol (Plasmodium falciparum)
Synthesis of IP2, IP, and Ins in the cytosol (Rattus norvegicus)
Synthesis of IP2, IP, and Ins in the cytosol (Saccharomyces cerevisiae)
Synthesis of IP2, IP, and Ins in the cytosol (Schizosaccharomyces pombe)
Synthesis of IP2, IP, and Ins in the cytosol (Sus scrofa)
Synthesis of IP2, IP, and Ins in the cytosol (Xenopus tropicalis)
Authored
Williams, MG  (2011-10-28)
Reviewed
Wundenberg, T  (2012-11-07)
Created
Williams, MG  (2011-10-28)
Cite Us!