Reactome | I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol

I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol

Stable Identifier

R-HSA-1855180

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol

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Type I (INPP4A) and type II inositol-3,4-bisphosphate 4-phosphatase (INPP4B) dephosphorylate inositol 1,3,4-trisphosphate (I(1,3,4)P3) to inositol 1,3-bisphosphate (I(1,3)P2) (Norris et al. 1995, Norris et al. 1997).

Literature References

PubMed ID	Title	Journal	Year
7608176	The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase Auethavekiat, V, Majerus, PW, Norris, FA	J Biol Chem	1995
9295334	The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family Atkins, RC, Majerus, PW, Norris, FA	J Biol Chem	1997