I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol

Stable Identifier
R-HSA-1855232
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Inositol polyphosphate 1-phosphatase (INPP1) dephosphorylates inositol 1,3,4-trisphosphate (I(1,3,4)P3) to inositol 3,4-bisphosphate (I(3,4)P2) (York et al. 1993).

Literature References
PubMed ID Title Journal Year
8390685 Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase

York, JD, Veile, RA, Donis-Keller, H, Majerus, PW

Proc Natl Acad Sci U S A 1993
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
inositol-1,3,4-trisphosphate 1-phosphatase activity of INPP1:Mg2+ [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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