Reactome | SARS-CoV-2-host interactions

authored	[InstanceEdit:9757087] Shamovsky, Veronica, 2021-10-27 [InstanceEdit:9729688] Stephan, Ralf, 2021-05-03
created	[InstanceEdit:9705656] Shamovsky, Veronica, 2020-10-28
crossReference	[DatabaseIdentifier:12020746] Mondo:0100096
dbId	9705683
disease	[Disease:9683912] COVID-19
displayName	SARS-CoV-2-host interactions
doi	10.3180/R-HSA-9705683.1
edited	[InstanceEdit:9766200] Shamovsky, Veronica, 2022-02-18
eventOf	[Pathway:R-HSA-9694516] SARS-CoV-2 Infection - Homo sapiens
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-HSA-9705671] SARS-CoV-2 activates/modulates innate and adaptive immune responses - Homo sapiens [Pathway:R-HSA-9705677] SARS-CoV-2 targets PDZ proteins in cell-cell junction - Homo sapiens [Pathway:R-HSA-9754560] SARS-CoV-2 modulates autophagy - Homo sapiens [Pathway:R-HSA-9754678] SARS-CoV-2 modulates host translation machinery - Homo sapiens [Pathway:R-HSA-9755779] SARS-CoV-2 targets host intracellular signalling and regulatory pathways - Homo sapiens
isInDisease	true
isInferred	false
lastUpdatedDate	2023-03-29
literatureReference	[LiteratureReference:9679510] Human Coronavirus: Host-Pathogen Interaction [LiteratureReference:9756653] Innate immune and inflammatory responses to SARS-CoV-2: Implications for COVID-19 [LiteratureReference:9754567] Manipulation of autophagy by SARS-CoV-2 proteins [LiteratureReference:9729781] SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses [LiteratureReference:9756764] Mechanisms of Antiviral Immune Evasion of SARS-CoV-2 [LiteratureReference:9756777] Cellular host factors for SARS-CoV-2 infection [LiteratureReference:9756767] Dysregulation of Cell Signaling by SARS-CoV-2
maxDepth	3
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	SARS-CoV-2-host interactions
relatedSpecies	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
releaseDate	2022-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9766195] Messina, Francesco, 2022-02-18 [InstanceEdit:9767748] Gillespie, Marc E, 2022-03-01
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9705683
summation	[Summation:9705659] Coronaviruses are a group of enveloped viruses with single?s...
updateTrackers	[UpdateTracker:9846719] Update Tracker - [Pathway:9705683] SARS-CoV-2-host interactions - v84:[updateIndirectRLE] [UpdateTracker:9774717] Update Tracker - [Pathway:9705683] SARS-CoV-2-host interactions - v81:[updateIndirectRLE]

(hasEvent)	[Pathway:R-HSA-9694516] SARS-CoV-2 Infection
(hasEncapsulatedEvent)	[Pathway:R-HSA-157858] Gap junction trafficking and regulation [Pathway:R-HSA-168643] Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways [Pathway:R-HSA-445989] TAK1-dependent IKK and NF-kappa-B activation [Pathway:R-HSA-909733] Interferon alpha/beta signaling [Pathway:R-HSA-983169] Class I MHC mediated antigen processing & presentation [Pathway:R-HSA-446728] Cell junction organization [Pathway:R-HSA-1257604] PIP3 activates AKT signaling [Pathway:R-HSA-168928] DDX58/IFIH1-mediated induction of interferon-alpha/beta [Pathway:R-HSA-194441] Metabolism of non-coding RNA [Pathway:R-HSA-448424] Interleukin-17 signaling
(updatedInstance)	[UpdateTracker:9846719] Update Tracker - [Pathway:9705683] SARS-CoV-2-host interactions - v84:[updateIndirectRLE] [UpdateTracker:9774717] Update Tracker - [Pathway:9705683] SARS-CoV-2-host interactions - v81:[updateIndirectRLE]

SARS-CoV-2-host interactions Show undefined attributes

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