Reactome | Interleukin-17 signaling

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Interleukin-17 signaling Show undefined attributes

authored	[InstanceEdit:5578882] Jupe, Steve, 2014-06-04
created	[InstanceEdit:448455] Jupe, S, 2009-11-24
crossReference	[DatabaseIdentifier:12819451] BioModels Database:BIOMD0000000477
dbId	448424
displayName	Interleukin-17 signaling
edited	[InstanceEdit:8854731] Jupe, Steve, 2016-01-28
eventOf	[Pathway:R-HSA-449147] Signaling by Interleukins - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:2588173] interleukin-17-mediated signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[BlackBoxEvent:R-HSA-447246] IL17RA and IL17RC bind IL17A dimer,IL17F dimer,IL17A:IL17F - Homo sapiens [BlackBoxEvent:R-HSA-447219] IL17RA and IL17RB bind IL25 dimer - Homo sapiens [BlackBoxEvent:R-HSA-5678544] IL17RA:IL17RE binds IL17C dimer - Homo sapiens [Pathway:R-HSA-450294] MAP kinase activation - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2022-04-07
literatureReference	[LiteratureReference:5678570] IL-17 family: cytokines, receptors and signaling
maxDepth	6
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	Interleukin-17 signaling
orthologousEvent	[Pathway:R-PFA-448424] Interleukin-17 signaling - Plasmodium falciparum [Pathway:R-SCE-448424] Interleukin-17 signaling - Saccharomyces cerevisiae [Pathway:R-SPO-448424] Interleukin-17 signaling - Schizosaccharomyces pombe [Pathway:R-DDI-448424] Interleukin-17 signaling - Dictyostelium discoideum [Pathway:R-CEL-448424] Interleukin-17 signaling - Caenorhabditis elegans [Pathway:R-DME-448424] Interleukin-17 signaling - Drosophila melanogaster [Pathway:R-GGA-448424] Interleukin-17 signaling - Gallus gallus [Pathway:R-XTR-448424] Interleukin-17 signaling - Xenopus tropicalis [Pathway:R-DRE-448424] Interleukin-17 signaling - Danio rerio [Pathway:R-SSC-448424] Interleukin-17 signaling - Sus scrofa [Pathway:R-BTA-448424] Interleukin-17 signaling - Bos taurus [Pathway:R-CFA-448424] Interleukin-17 signaling - Canis familiaris [Pathway:R-RNO-448424] Interleukin-17 signaling - Rattus norvegicus [Pathway:R-MMU-448424] Interleukin-17 signaling - Mus musculus
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8854753] Meldal, Birgit, 2016-01-28
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-448424
summation	[Summation:5678554] Interleukin-17 (IL17) is a family of cytokines (Kawaguchi et...
updateTrackers	[UpdateTracker:9782031] Update Tracker - [Pathway:448424] Interleukin-17 signaling - v60:[addHasEvent, updateContainedPathway, updateContainedRLE] [UpdateTracker:9775224] Update Tracker - [Pathway:448424] Interleukin-17 signaling - v80:[updateContainedRLE] [UpdateTracker:9780526] Update Tracker - [Pathway:448424] Interleukin-17 signaling - v62:[removeHasEvent] [UpdateTracker:9780228] Update Tracker - [Pathway:448424] Interleukin-17 signaling - v63:[modifyText, updateContainedRLE] [UpdateTracker:9781174] Update Tracker - [Pathway:448424] Interleukin-17 signaling - v61:[modifyText, updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9782031] Update Tracker - [Pathway:448424] Interleukin-17 signaling - v60:[addHasEvent, updateContainedPathway, updateContainedRLE] [UpdateTracker:9775224] Update Tracker - [Pathway:448424] Interleukin-17 signaling - v80:[updateContainedRLE] [UpdateTracker:9780526] Update Tracker - [Pathway:448424] Interleukin-17 signaling - v62:[removeHasEvent] [UpdateTracker:9780228] Update Tracker - [Pathway:448424] Interleukin-17 signaling - v63:[modifyText, updateContainedRLE] [UpdateTracker:9781174] Update Tracker - [Pathway:448424] Interleukin-17 signaling - v61:[modifyText, updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-449147] Signaling by Interleukins
(hasEncapsulatedEvent)	[Pathway:R-HSA-9705683] SARS-CoV-2-host interactions

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