Reactome | SOX10 [nucleoplasm]

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SOX10 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9613641] POU3F1 gene:SOX10 dimer:HDAC2:SMARCA4 [nucleoplasm] - Homo sapiens [Complex:R-HSA-9613641] POU3F1 gene:SOX10 dimer:HDAC2:SMARCA4 [nucleoplasm] - Homo sapiens [Complex:R-HSA-9730398] SOX10:PAX3:MITF gene [nucleoplasm] - Homo sapiens [Complex:R-HSA-9825863] MITF-M dimer:SOX10:p-S133 CREB1:LEF1:CTNNB1:DCT gene [nucleoplasm] - Homo sapiens [Complex:R-HSA-9613761] EGR2 gene:POU3F1:POU3F2:SOX10 [nucleoplasm] - Homo sapiens [Complex:R-HSA-9613761] EGR2 gene:POU3F1:POU3F2:SOX10 [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9824582] MAPK1 phosphorylates SOX10 - Homo sapiens [Reaction:R-HSA-9616116] EGR2 and SOX10 bind the MAG gene - Homo sapiens [Reaction:R-HSA-9616116] EGR2 and SOX10 bind the MAG gene - Homo sapiens [Reaction:R-HSA-9730407] SOX10 and PAX3 bind the MITF promoter - Homo sapiens [Reaction:R-HSA-9613648] SOX10 dimer binds the POU3F1 promoter - Homo sapiens [Reaction:R-HSA-9613648] SOX10 dimer binds the POU3F1 promoter - Homo sapiens [Reaction:R-HSA-9773192] SOX10 binds CDH19 gene promoter - Homo sapiens [Reaction:R-HSA-9618725] SOX10, EGR2 and NAB proteins bind the GJB1 promoter - Homo sapiens [Reaction:R-HSA-9618725] SOX10, EGR2 and NAB proteins bind the GJB1 promoter - Homo sapiens [Reaction:R-HSA-9825848] MITF-M dimer, SOX10, pS133 CREB1 and CTNNB1:LEF1 bind the DCT promoter - Homo sapiens [Reaction:R-HSA-9618559] EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene - Homo sapiens [Reaction:R-HSA-9618559] EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene - Homo sapiens [Reaction:R-HSA-9615638] EGR2 and SOX10 bind the MBP gene - Homo sapiens [Reaction:R-HSA-9615638] EGR2 and SOX10 bind the MBP gene - Homo sapiens [Reaction:R-HSA-9619657] EGR2 and SOX10 bind the PRX gene - Homo sapiens [Reaction:R-HSA-9619657] EGR2 and SOX10 bind the PRX gene - Homo sapiens [Reaction:R-HSA-9613768] SOX10, POU3F1 and POU3F2 bind EGR2 gene - Homo sapiens [Reaction:R-HSA-9613768] SOX10, POU3F1 and POU3F2 bind EGR2 gene - Homo sapiens [Reaction:R-HSA-9614790] EGR2, SOX10 and SMARCA4 bind the MPZ gene - Homo sapiens [Reaction:R-HSA-9614790] EGR2, SOX10 and SMARCA4 bind the MPZ gene - Homo sapiens
created	[InstanceEdit:9613640] Rothfels, Karen, 2018-07-16
dbId	9613639
displayName	SOX10 [nucleoplasm]
endCoordinate	466
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-9692084] Sox10 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-9614292] Sox10 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-9613639] SOX10 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-9613639] SOX10 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-9613639] SOX10 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-SSC-9613639-2] SOX10 [nucleoplasm] - Sus scrofa [DefinedSet:R-SSC-9613639-3] Homologues of SOX10 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-9613639] sox10 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-9613639] sox10 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-9613639] SOX10 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-9613639] Sox100B [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-SPO-9613639] ste11 [nucleoplasm] - Schizosaccharomyces pombe
maxDepth	1
name	SOX10 Transcription factor SOX-10 SOX10_HUMAN
referenceEntity	[ReferenceGeneProduct:uniprot:P56693] UniProt:P56693 SOX10
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9613639
startCoordinate	1

Referrals

(input)	[Reaction:R-HSA-9824582] MAPK1 phosphorylates SOX10 [Reaction:R-HSA-9825848] MITF-M dimer, SOX10, pS133 CREB1 and CTNNB1:LEF1 bind the DCT promoter [Reaction:R-HSA-9730407] SOX10 and PAX3 bind the MITF promoter [Reaction:R-HSA-9616116] EGR2 and SOX10 bind the MAG gene [Reaction:R-HSA-9618559] EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene [Reaction:R-HSA-9613768] SOX10, POU3F1 and POU3F2 bind EGR2 gene [Reaction:R-HSA-9614790] EGR2, SOX10 and SMARCA4 bind the MPZ gene [Reaction:R-HSA-9615638] EGR2 and SOX10 bind the MBP gene [Reaction:R-HSA-9613648] SOX10 dimer binds the POU3F1 promoter [Reaction:R-HSA-9619657] EGR2 and SOX10 bind the PRX gene [Reaction:R-HSA-9773192] SOX10 binds CDH19 gene promoter [Reaction:R-HSA-9618725] SOX10, EGR2 and NAB proteins bind the GJB1 promoter
(activeUnit)	[PositiveGeneExpressionRegulation:9825891] Positive gene expression regulation by 'MITF-M dimer:SOX10:p-S133 CREB1:LEF1:CTNNB1:DCT gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9730409] Positive gene expression regulation by 'SOX10:PAX3:MITF gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9616128] Positive gene expression regulation by 'MAG gene:EGR2:SOX10 [nucleoplasm]' [PositiveGeneExpressionRegulation:9615630] Positive gene expression regulation by 'MBP gene:EGR2:SOX10 [nucleoplasm]' [PositiveGeneExpressionRegulation:9613645] Positive gene expression regulation by 'POU3F1 gene:SOX10 dimer:HDAC2:SMARCA4 [nucleoplasm]' [PositiveGeneExpressionRegulation:9618565] Positive gene expression regulation by 'PMP22 gene:EGR2:SOX10:TEAD1:WWTR1,YAP1 [nucleoplasm]' [PositiveGeneExpressionRegulation:9613762] Positive gene expression regulation by 'EGR2 gene:POU3F1:POU3F2:SOX10 [nucleoplasm]' [PositiveGeneExpressionRegulation:9614782] Positive gene expression regulation by 'MPZ gene:EGR2:SOX10:SMARCA4 [nucleoplasm]' [PositiveGeneExpressionRegulation:9619644] Positive gene expression regulation by 'PRX gene:EGR2:SOX10 [nucleoplasm]' [PositiveGeneExpressionRegulation:9774245] Positive gene expression regulation by 'SOX10:CDH19 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9618736] Positive gene expression regulation by 'GJB11 gene:SOX10:EGR2:NAB1,2 [nucleoplasm]'
(hasComponent)	[Complex:R-HSA-9825863] MITF-M dimer:SOX10:p-S133 CREB1:LEF1:CTNNB1:DCT gene [nucleoplasm] [Complex:R-HSA-9730398] SOX10:PAX3:MITF gene [nucleoplasm] [Complex:R-HSA-9616114] MAG gene:EGR2:SOX10 [nucleoplasm] [Complex:R-HSA-9618555] PMP22 gene:EGR2:SOX10:TEAD1:WWTR1,YAP1 [nucleoplasm] [Complex:R-HSA-9613761] EGR2 gene:POU3F1:POU3F2:SOX10 [nucleoplasm] [Complex:R-HSA-9614793] MPZ gene:EGR2:SOX10:SMARCA4 [nucleoplasm] [Complex:R-HSA-9615629] MBP gene:EGR2:SOX10 [nucleoplasm] [Complex:R-HSA-9613641] POU3F1 gene:SOX10 dimer:HDAC2:SMARCA4 [nucleoplasm] [Complex:R-HSA-9619633] PRX gene:EGR2:SOX10 [nucleoplasm] [Complex:R-HSA-9774224] SOX10:CDH19 gene [nucleoplasm] [Complex:R-HSA-9618726] GJB11 gene:SOX10:EGR2:NAB1,2 [nucleoplasm]

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