Reactome | EGR2 and SOX10 bind the MAG gene

Schema > Reaction > Entries

EGR2 and SOX10 bind the MAG gene Show undefined attributes

authored	[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9616115] Rothfels, Karen, 2018-08-09
dbId	9616116
displayName	EGR2 and SOX10 bind the MAG gene
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
eventOf	[Pathway:R-HSA-9619665] EGR2 and SOX10-mediated initiation of Schwann cell myelination - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9614778] MAG gene expression - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-977385] EGR2 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9614777] MAG gene [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-HSA-9613639] SOX10 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9615605] Interactions of Sox10 and Egr2 in myelin gene regulation [LiteratureReference:9615601] In vivo detection of Egr2 binding to target genes during peripheral nerve myelination [LiteratureReference:9613730] Neuropathy-associated Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	EGR2 and SOX10 bind the MAG gene
output	[Complex:R-HSA-9616114] MAG gene:EGR2:SOX10 [nucleoplasm]
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9616116
summation	[Summation:9616113] EGR2 and SOX10 bind to elements in the MAG gene to promote e...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-9614778] MAG gene expression
(hasEvent)	[Pathway:R-HSA-9619665] EGR2 and SOX10-mediated initiation of Schwann cell myelination

Cite Us!