Reactome | SOX10, POU3F1 and POU3F2 bind EGR2 gene

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SOX10, POU3F1 and POU3F2 bind EGR2 gene Show undefined attributes

authored	[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9613767] Rothfels, Karen, 2018-07-18
dbId	9613768
displayName	SOX10, POU3F1 and POU3F2 bind EGR2 gene
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
eventOf	[Pathway:R-HSA-9619665] EGR2 and SOX10-mediated initiation of Schwann cell myelination - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9613760] EGR2 gene expression - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9612057] EGR2 gene [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9613634] POU3F1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9613754] POU3F2 [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-HSA-9613639] SOX10 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9613705] The molecular machinery of myelin gene transcription in Schwann cells [LiteratureReference:9613749] Control of myelination in Schwann cells: a Krox20 cis-regulatory element integrates Oct6, Brn2 and Sox10 activities [LiteratureReference:9614261] Activation of Krox20 gene expression by Sox10 in myelinating Schwann cells [LiteratureReference:9613933] HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells [LiteratureReference:9614286] HDAC-mediated deacetylation of NF-?B is critical for Schwann cell myelination [LiteratureReference:9613916] Chromatin-remodeling factor Brg1 is required for Schwann cell differentiation and myelination
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SOX10, POU3F1 and POU3F2 bind EGR2 gene
output	[Complex:R-HSA-9613761] EGR2 gene:POU3F1:POU3F2:SOX10 [nucleoplasm]
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9613768
summation	[Summation:9614307] During the process of peripheral nerve myelination, EGR2 exp...

Referrals

(hasEvent)	[Pathway:R-HSA-9619665] EGR2 and SOX10-mediated initiation of Schwann cell myelination
(precedingEvent)	[BlackBoxEvent:R-HSA-9613760] EGR2 gene expression