Reactome | NCOA3 [nucleoplasm]

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NCOA3 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9011926] GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm] - Homo sapiens [Complex:R-HSA-5617470] atRA:RARA,G:RXRA at active HOXB1 chromatin [nucleoplasm] - Homo sapiens [Complex:R-HSA-5617448] atRA:RARA,G:RXRA at active HOXA1 chromatin [nucleoplasm] - Homo sapiens [Complex:R-HSA-9011883] MYC gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300:NCOA3 [nucleoplasm] - Homo sapiens [Complex:R-HSA-381367] PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9008258] NCOA3 binds ESR1:estrogen:TFGA gene - Homo sapiens [Reaction:R-HSA-5687090] p-S MAPK6 phosphorylates NCOA3 - Homo sapiens [BlackBoxEvent:R-HSA-9012000] NR5A2, ZNF217 and NCOA3 bind GREB1 promoter - Homo sapiens [BlackBoxEvent:R-HSA-5617859] Retinoic acid activates HOXB4 chromatin - Homo sapiens [BlackBoxEvent:R-HSA-5617452] Retinoic acid activates HOXB1 chromatin - Homo sapiens [BlackBoxEvent:R-HSA-5617896] Retinoic acid activates HOXD4 chromatin - Homo sapiens [BlackBoxEvent:R-HSA-5617431] Retinoic acid activates HOXA1 chromatin - Homo sapiens [BlackBoxEvent:R-HSA-5617862] Retinoic acid activates HOXA4 chromatin - Homo sapiens [Reaction:R-HSA-381309] PPARG:RXRA heterodimer binds to fatty acid-like ligands - Homo sapiens
created	[InstanceEdit:442522] May, B, 2009-09-27
dbId	442488
displayName	NCOA3 [nucleoplasm]
endCoordinate	1424
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-442488] Ncoa3 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-442488] Ncoa3 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-442488] NCOA3 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-442488] NCOA3 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-442488] NCOA3 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-XTR-442488] ncoa3 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-442488] NCOA3 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-442488] tai [nucleoplasm] - Drosophila melanogaster
memberOf	[CandidateSet:R-HSA-9023843] NCOAs [nucleoplasm] - Homo sapiens [DefinedSet:R-HSA-9023864] NCOA1,NCOA3 [nucleoplasm] - Homo sapiens
modified	[InstanceEdit:3448660] Wu, G, 2013-05-16
name	NCOA3 Nuclear receptor coactivator 3 NCOA3_HUMAN
referenceEntity	[ReferenceGeneProduct:416136] UniProt:Q9Y6Q9 NCOA3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-442488
startCoordinate	1

Referrals

(hasMember)	[DefinedSet:R-HSA-9023864] NCOA1,NCOA3 [nucleoplasm] [CandidateSet:R-HSA-9023843] NCOAs [nucleoplasm]
(hasComponent)	[Complex:R-HSA-9011926] GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm] [Complex:R-HSA-9011883] MYC gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300:NCOA3 [nucleoplasm] [Complex:R-HSA-9008244] ESR1:estrogen:ERE:NCOA3:TFGA gene [nucleoplasm] [Complex:R-HSA-381367] PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] [Complex:R-HSA-5617888] atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] [Complex:R-HSA-5617861] atRA:RARA,B:RXRA at active HOXD4 chromatin [nucleoplasm] [Complex:R-HSA-5617470] atRA:RARA,G:RXRA at active HOXB1 chromatin [nucleoplasm] [Complex:R-HSA-5617448] atRA:RARA,G:RXRA at active HOXA1 chromatin [nucleoplasm] [Complex:R-HSA-5617873] atRA:RARA,B:RXRA at active HOXA4 chromatin [nucleoplasm]
(input)	[BlackBoxEvent:R-HSA-9012000] NR5A2, ZNF217 and NCOA3 bind GREB1 promoter [Reaction:R-HSA-9008258] NCOA3 binds ESR1:estrogen:TFGA gene [Reaction:R-HSA-5687090] p-S MAPK6 phosphorylates NCOA3 [Reaction:R-HSA-381309] PPARG:RXRA heterodimer binds to fatty acid-like ligands [BlackBoxEvent:R-HSA-5617859] Retinoic acid activates HOXB4 chromatin [BlackBoxEvent:R-HSA-5617896] Retinoic acid activates HOXD4 chromatin [BlackBoxEvent:R-HSA-5617452] Retinoic acid activates HOXB1 chromatin [BlackBoxEvent:R-HSA-5617431] Retinoic acid activates HOXA1 chromatin [BlackBoxEvent:R-HSA-5617862] Retinoic acid activates HOXA4 chromatin
(activeUnit)	[PositiveGeneExpressionRegulation:R-HSA-5634074] Positive gene expression regulation by 'atRA:RARA,G:RXRA at active HOXA1 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634093] Positive gene expression regulation by 'atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634091] Positive gene expression regulation by 'atRA:RARA,B:RXRA at active HOXD4 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634072] Positive gene expression regulation by 'atRA:RARA,G:RXRA at active HOXB1 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634068] Positive gene expression regulation by 'atRA:RARA,B:RXRA at active HOXA4 chromatin [nucleoplasm]'

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