Reactome | atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm]

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5617850] May, Bruce, 2014-08-15
dbId	5617888
displayName	atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-381325] EP300 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5617892] HOXB4 gene [nucleoplasm] [DefinedSet:R-HSA-5619379] MLL3,4 complex [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-442488] NCOA3 [nucleoplasm] [Complex:R-HSA-1214169] Nucleosome with H3K4me3 [nucleoplasm] [Complex:R-HSA-209680] RNA Polymerase II holoenzyme complex (generic) [nucleoplasm] [Complex:R-HSA-5617890] RXRA:RARA,B:atRA [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-MMU-5619406] atRA:Rara,b:Rxra at active Hoxb4 chromatin [nucleoplasm] - Mus musculus
isChimeric	false
literatureReference	[LiteratureReference:4687099] A histone H3 lysine 27 demethylase regulates animal posterior development [LiteratureReference:4687095] Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination
maxDepth	6
modified	[InstanceEdit:6810175] May, Bruce, 2015-11-16
name	atRA:RARA,B:RXRA at active HOXB4 chromatin
positivelyRegulates	[PositiveGeneExpressionRegulation:R-HSA-5634093] Positive gene expression regulation by 'atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm]'
producedByEvent	[BlackBoxEvent:R-HSA-5617859] Retinoic acid activates HOXB4 chromatin - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5617888
updateTrackers	[UpdateTracker:9906575] Update Tracker - [Complex:5617888] atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] - v87:[updateContainedComponent] [UpdateTracker:9894469] Update Tracker - [Complex:5617888] atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] - v57:[updateContainedComponent] [UpdateTracker:9905012] Update Tracker - [Complex:5617888] atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] - v84:[updateContainedComponent]

atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] Show undefined attributes

Referrals

(updatedInstance)	[UpdateTracker:9906575] Update Tracker - [Complex:5617888] atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] - v87:[updateContainedComponent] [UpdateTracker:9894469] Update Tracker - [Complex:5617888] atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] - v57:[updateContainedComponent] [UpdateTracker:9905012] Update Tracker - [Complex:5617888] atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] - v84:[updateContainedComponent]
(inferredTo)	[Complex:R-MMU-5619406] atRA:Rara,b:Rxra at active Hoxb4 chromatin [nucleoplasm]
(output)	[BlackBoxEvent:R-HSA-5617859] Retinoic acid activates HOXB4 chromatin
(regulator)	[PositiveGeneExpressionRegulation:R-HSA-5634093] Positive gene expression regulation by 'atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm]'