Reactome | p-T32,S253,S315-FOXO3 [nucleoplasm]

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[BlackBoxEvent:R-HSA-9699581] AKT-phosphorylated FOXO3 translocates to cytosol - Homo sapiens [BlackBoxEvent:R-HSA-9624527] AKT-phosphorylated FOXO3 translocates to cytosol - Homo sapiens
created	[InstanceEdit:199263] Jassal, B, 2007-07-10 07:58:55
dbId	199289
displayName	p-T32,S253,S315-FOXO3 [nucleoplasm]
endCoordinate	673
hasModifiedResidue	[ModifiedResidue:199267] O-phospho-L-serine at 253 [ModifiedResidue:199280] O-phospho-L-serine at 315 [ModifiedResidue:199297] O-phospho-L-threonine at 32
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-199289] phospho-Foxo3 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-199289] phospho-Foxo3 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-199289] phospho-FOXO3 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-199289] phospho-FOXO3 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-199289] phospho-FOXO3 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-199289] phospho-foxo3b [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-199289] phospho-foxo3 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-DME-199289] phospho-foxo [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-199289] phospho-daf-16 [nucleoplasm] - Caenorhabditis elegans
maxDepth	1
memberOf	[DefinedSet:R-HSA-199269] p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4 [nucleoplasm] - Homo sapiens
modified	[InstanceEdit:4084615] Orlic-Milacic, M, 2013-07-29
name	p-T32,S253,S315-FOXO3 Phospho-Forkhead box protein O3A (T32, S253, S315) FOXO3_HUMAN FOXO3A
producedByEvent	[Reaction:R-HSA-9699579] AKT phosphorylates FOXO3 downstream of FLT3 - Homo sapiens [Reaction:R-HSA-9624526] AKT phosphorylates FOXO3 downstream of ESR1 and EGFR - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:O43524] UniProt:O43524 FOXO3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-199289
startCoordinate	2
updateTrackers	[UpdateTracker:9882325] Update Tracker - [EntityWithAccessionedSequence:199289] p-T32,S253,S315-FOXO3 [nucleoplasm] - v45:[addName] [UpdateTracker:9873084] Update Tracker - [EntityWithAccessionedSequence:199289] p-T32,S253,S315-FOXO3 [nucleoplasm] - v42:[addName] [UpdateTracker:9888235] Update Tracker - [EntityWithAccessionedSequence:199289] p-T32,S253,S315-FOXO3 [nucleoplasm] - v46:[modifyStartCoordinate, removeName]

(updatedInstance)	[UpdateTracker:9882325] Update Tracker - [EntityWithAccessionedSequence:199289] p-T32,S253,S315-FOXO3 [nucleoplasm] - v45:[addName] [UpdateTracker:9873084] Update Tracker - [EntityWithAccessionedSequence:199289] p-T32,S253,S315-FOXO3 [nucleoplasm] - v42:[addName] [UpdateTracker:9888235] Update Tracker - [EntityWithAccessionedSequence:199289] p-T32,S253,S315-FOXO3 [nucleoplasm] - v46:[modifyStartCoordinate, removeName]
(output)	[Reaction:R-HSA-9699579] AKT phosphorylates FOXO3 downstream of FLT3 [Reaction:R-HSA-9624526] AKT phosphorylates FOXO3 downstream of ESR1 and EGFR
(input)	[BlackBoxEvent:R-HSA-9699581] AKT-phosphorylated FOXO3 translocates to cytosol [BlackBoxEvent:R-HSA-9624527] AKT-phosphorylated FOXO3 translocates to cytosol
(hasMember)	[DefinedSet:R-HSA-199269] p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4 [nucleoplasm] [CandidateSet:R-HSA-9614997] p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4,(p-T26,S184-FOXO6) [nucleoplasm]

p-T32,S253,S315-FOXO3 [nucleoplasm] Show undefined attributes

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