Reactome | phospho-foxo [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[BlackBoxEvent:R-DME-9699581] AKT-phosphorylated FOXO3 translocates to cytosol - Drosophila melanogaster [BlackBoxEvent:R-DME-9624527] AKT-phosphorylated FOXO3 translocates to cytosol - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10843217
displayName	phospho-foxo [nucleoplasm]
endCoordinate	673
hasModifiedResidue	[ModifiedResidue:10843213] O-phospho-L-serine at 253 (in Homo sapiens) [ModifiedResidue:10843214] O-phospho-L-serine at 315 (in Homo sapiens) [ModifiedResidue:10843215] O-phospho-L-threonine at 32 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-199289] p-T32,S253,S315-FOXO3 [nucleoplasm] - Homo sapiens
maxDepth	1
name	phospho-foxo p-T32,S253,S315-FOXO3 Q95V55
producedByEvent	[Reaction:R-DME-9699579] AKT phosphorylates FOXO3 downstream of FLT3 - Drosophila melanogaster [Reaction:R-DME-9624526] AKT phosphorylates FOXO3 downstream of ESR1 and EGFR - Drosophila melanogaster
referenceEntity	[ReferenceGeneProduct:uniprot:Q95V55] UniProt:Q95V55 foxo
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:56210] Drosophila melanogaster
stId	R-DME-199289
startCoordinate	2

(input)	[BlackBoxEvent:R-DME-9699581] AKT-phosphorylated FOXO3 translocates to cytosol [BlackBoxEvent:R-DME-9624527] AKT-phosphorylated FOXO3 translocates to cytosol
(output)	[Reaction:R-DME-9699579] AKT phosphorylates FOXO3 downstream of FLT3 [Reaction:R-DME-9624526] AKT phosphorylates FOXO3 downstream of ESR1 and EGFR
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-199289] p-T32,S253,S315-FOXO3 [nucleoplasm]

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