Reactome | CDC42:GTP [plasma membrane]

Schema > Complex > Entries

CDC42:GTP [plasma membrane] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-9959034] RAC1:GTP,(CDC42:GTP) [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9013240] CDC42:GTP:CDC42 effectors [plasma membrane] - Homo sapiens [Complex:R-HSA-418820] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9013157] CDC42 binds effectors at the plasma membrane - Homo sapiens [BlackBoxEvent:R-HSA-9692800] CDC42 translocates to the endoplasmic reticulum membrane - Homo sapiens [Reaction:R-HSA-9013161] CDC42 GAPs stimulate CDC42 GTPase activity - Homo sapiens [Reaction:R-NUL-428519] Inactivation of Cdc42 - Rattus norvegicus [Reaction:R-HSA-428533] Inactivation of CDC42 - Homo sapiens [Reaction:R-HSA-376119] Interaction of Bnip-2 with Cdc42 - Homo sapiens [Reaction:R-HSA-5665727] FMNL2 binds CDC42:GTP - Homo sapiens [Reaction:R-HSA-5665686] FMNL1 binds CDC42:GTP - Homo sapiens [Reaction:R-HSA-442586] Activation of WASP and N-WASP by CDC42 - Homo sapiens [Reaction:R-HSA-9670155] CDC42:GTP binds PtdIns(4,5)P2:WASP,N-WASP - Homo sapiens
created	[InstanceEdit:182919] Jassal, B, 2006-07-21 10:17:37
dbId	182921
displayName	CDC42:GTP [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-449545] CDC42 [plasma membrane] [SimpleEntity:R-ALL-29438] GTP [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-448879] Cdc42:GTP [plasma membrane] - Mus musculus [Complex:R-RNO-182921] CDC42:GTP [plasma membrane] - Rattus norvegicus [Complex:R-CFA-182921] CDC42:GTP [plasma membrane] - Canis familiaris [Complex:R-BTA-182921] CDC42:GTP [plasma membrane] - Bos taurus [Complex:R-SSC-182921] CDC42:GTP [plasma membrane] - Sus scrofa [Complex:R-DRE-182921] CDC42:GTP [plasma membrane] - Danio rerio [Complex:R-XTR-182921] CDC42:GTP [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-182921] CDC42:GTP [plasma membrane] - Gallus gallus [Complex:R-DME-182921] CDC42:GTP [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-182921] CDC42:GTP [plasma membrane] - Caenorhabditis elegans [Complex:R-SPO-182921] CDC42:GTP [plasma membrane] - Schizosaccharomyces pombe [Complex:R-SCE-182921] CDC42:GTP [plasma membrane] - Saccharomyces cerevisiae
maxDepth	2
memberOf	[DefinedSet:R-HSA-389778] CDC42:GTP, RAC1:GTP [plasma membrane] - Homo sapiens
modified	[InstanceEdit:5634775] Orlic-Milacic, Marija, 2014-11-06
name	CDC42:GTP CDC42-GTP
producedByEvent	[Reaction:R-HSA-9013159] CDC42 GEFs activate CDC42 - Homo sapiens [Reaction:R-HSA-389350] Activation of Cdc42 by pVav1 - Homo sapiens [BlackBoxEvent:R-HSA-2029445] An unknown GEF exchanges GTP for GDP on CDC42:GDP - Homo sapiens [Reaction:R-HSA-8964599] Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-182921
updateTrackers	[UpdateTracker:9868475] Update Tracker - [Complex:182921] CDC42:GTP [plasma membrane] - v31:[add_removeHasComponent, modifyName] [UpdateTracker:9870257] Update Tracker - [Complex:182921] CDC42:GTP [plasma membrane] - v38:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9868475] Update Tracker - [Complex:182921] CDC42:GTP [plasma membrane] - v31:[add_removeHasComponent, modifyName] [UpdateTracker:9870257] Update Tracker - [Complex:182921] CDC42:GTP [plasma membrane] - v38:[addName]
(hasComponent)	[Complex:R-HSA-9013240] CDC42:GTP:CDC42 effectors [plasma membrane] [Complex:R-HSA-3928566] p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] [Complex:R-HSA-448875] Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] [Complex:R-HSA-9014577] G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] [Complex:R-HSA-8964618] G-protein beta-gamma complex:PAK1:ARHGEF6:Active CDC42 [plasma membrane] [Complex:R-HSA-5665735] CDC42:GTP:FMNL2 [plasma membrane] [Complex:R-HSA-5665688] CDC42:GTP:FMNL1 [plasma membrane] [Complex:R-HSA-182915] Ub-Beta-Pix:CDC42:GTP [cytosol] [Complex:R-HSA-182917] Beta-Pix:CDC42:GTP [cytosol] [Complex:R-HSA-418820] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] [Complex:R-HSA-442584] CDC42:GTP:WASP/N-WASP [plasma membrane] [Complex:R-HSA-2197683] CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] [Complex:R-HSA-2197680] CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane]
(input)	[Reaction:R-HSA-9013157] CDC42 binds effectors at the plasma membrane [BlackBoxEvent:R-HSA-9692800] CDC42 translocates to the endoplasmic reticulum membrane [Reaction:R-HSA-9013161] CDC42 GAPs stimulate CDC42 GTPase activity [Reaction:R-NUL-428519] Inactivation of Cdc42 [Reaction:R-HSA-428533] Inactivation of CDC42 [Reaction:R-HSA-376119] Interaction of Bnip-2 with Cdc42 [Reaction:R-HSA-5665727] FMNL2 binds CDC42:GTP [Reaction:R-HSA-5665686] FMNL1 binds CDC42:GTP [Reaction:R-HSA-442586] Activation of WASP and N-WASP by CDC42 [Reaction:R-HSA-9670155] CDC42:GTP binds PtdIns(4,5)P2:WASP,N-WASP
(output)	[Reaction:R-HSA-9013159] CDC42 GEFs activate CDC42 [Reaction:R-HSA-8964599] Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex [Reaction:R-HSA-389350] Activation of Cdc42 by pVav1 [BlackBoxEvent:R-HSA-2029445] An unknown GEF exchanges GTP for GDP on CDC42:GDP
(hasMember)	[DefinedSet:R-HSA-389778] CDC42:GTP, RAC1:GTP [plasma membrane]
(hasCandidate)	[CandidateSet:R-HSA-9959034] RAC1:GTP,(CDC42:GTP) [plasma membrane]

Cite Us!