Reactome | CDC42:GTP [plasma membrane]

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CDC42:GTP [plasma membrane] Show undefined attributes

candidateOf	[CandidateSet:R-CFA-9959034] RAC1:GTP,(CDC42:GTP) [plasma membrane] - Canis familiaris
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-CFA-9013240] CDC42:GTP:CDC42 effectors [plasma membrane] - Canis familiaris [Complex:R-CFA-418820] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-9013157] CDC42 binds effectors at the plasma membrane - Canis familiaris [BlackBoxEvent:R-CFA-9692800] CDC42 translocates to the endoplasmic reticulum membrane - Canis familiaris [Reaction:R-CFA-9013161] CDC42 GAPs stimulate CDC42 GTPase activity - Canis familiaris [Reaction:R-CFA-5218832] CDC42:GTP binds PAK2 - Canis familiaris [Reaction:R-CFA-5218832] CDC42:GTP binds PAK2 - Canis familiaris [Reaction:R-CFA-5665727] FMNL2 binds CDC42:GTP - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10240940
displayName	CDC42:GTP [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-CFA-449545] CDC42 [plasma membrane] [SimpleEntity:R-ALL-29438] GTP [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-449518] CDC42:GTP [plasma membrane] - Homo sapiens [Complex:R-HSA-182921] CDC42:GTP [plasma membrane] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-CFA-389778] CDC42:GTP, RAC1:GTP [plasma membrane] - Canis familiaris
name	CDC42:GTP
producedByEvent	[Reaction:R-CFA-9013159] CDC42 GEFs activate CDC42 - Canis familiaris [Reaction:R-CFA-389350] Activation of Cdc42 by pVav1 - Canis familiaris [Reaction:R-CFA-8964599] Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-182921
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-CFA-9013157] CDC42 binds effectors at the plasma membrane [BlackBoxEvent:R-CFA-9692800] CDC42 translocates to the endoplasmic reticulum membrane [Reaction:R-CFA-9013161] CDC42 GAPs stimulate CDC42 GTPase activity [Reaction:R-CFA-5218832] CDC42:GTP binds PAK2 [Reaction:R-CFA-5665727] FMNL2 binds CDC42:GTP
(hasComponent)	[Complex:R-CFA-9013240] CDC42:GTP:CDC42 effectors [plasma membrane] [Complex:R-CFA-3928566] p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] [Complex:R-CFA-448875] Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] [Complex:R-CFA-9014577] G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] [Complex:R-CFA-5218772] p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] [Complex:R-CFA-5218800] p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] [Complex:R-CFA-5218770] PAK2 dimer:CDC42:GTP [plasma membrane] [Complex:R-CFA-5665735] CDC42:GTP:FMNL2 [plasma membrane] [Complex:R-CFA-182915] Ub-Beta-Pix:CDC42:GTP [cytosol] [Complex:R-CFA-182917] Beta-Pix:CDC42:GTP [cytosol] [Complex:R-CFA-418820] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] [Complex:R-CFA-442584] CDC42:GTP:WASP/N-WASP [plasma membrane] [Complex:R-CFA-2197683] CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] [Complex:R-CFA-2197680] CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane]
(output)	[Reaction:R-CFA-9013159] CDC42 GEFs activate CDC42 [Reaction:R-CFA-8964599] Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex [Reaction:R-CFA-389350] Activation of Cdc42 by pVav1
(inferredTo)	[Complex:R-HSA-449518] CDC42:GTP [plasma membrane] [Complex:R-HSA-182921] CDC42:GTP [plasma membrane]
(hasMember)	[DefinedSet:R-CFA-389778] CDC42:GTP, RAC1:GTP [plasma membrane]
(hasCandidate)	[CandidateSet:R-CFA-9959034] RAC1:GTP,(CDC42:GTP) [plasma membrane]

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