Reactome | CDC42:GTP [plasma membrane]

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CDC42:GTP [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-SPO-5672334] RAC1,CDC42:GTP:IQGAP1 [plasma membrane] - Schizosaccharomyces pombe [Complex:R-SPO-5626465] RAC1,CDC42:GTP:IQGAPs [plasma membrane] - Schizosaccharomyces pombe
consumedByEvent	[BlackBoxEvent:R-SPO-9692800] CDC42 translocates to the endoplasmic reticulum membrane - Schizosaccharomyces pombe [Reaction:R-SPO-9013161] CDC42 GAPs stimulate CDC42 GTPase activity - Schizosaccharomyces pombe [Reaction:R-SPO-389788] Activation of PAKs by RAC1 and CDC42 - Schizosaccharomyces pombe [Reaction:R-SPO-8981931] RAC1 and CDC42 activate PAK2 - Schizosaccharomyces pombe [Reaction:R-SPO-8981926] RAC1 and CDC42 activate PAK3 - Schizosaccharomyces pombe [Reaction:R-SPO-2029456] RAC1 and CDC42 activate PAK1 - Schizosaccharomyces pombe [Reaction:R-SPO-5626469] GTP-bound RAC1 and CDC42 bind IQGAPs - Schizosaccharomyces pombe
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11059669
displayName	CDC42:GTP [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-SPO-449545] CDC42 [plasma membrane] [SimpleEntity:R-ALL-29438] GTP [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-449518] CDC42:GTP [plasma membrane] - Homo sapiens [Complex:R-HSA-182921] CDC42:GTP [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-389778] CDC42:GTP, RAC1:GTP [plasma membrane] - Homo sapiens
maxDepth	2
name	CDC42:GTP
producedByEvent	[Reaction:R-SPO-9013159] CDC42 GEFs activate CDC42 - Schizosaccharomyces pombe [Reaction:R-SPO-2029454] Autophosphorylation of PAK1 - Schizosaccharomyces pombe [Reaction:R-SPO-5627775] Autophosphorylation of PAK1,2,3 - Schizosaccharomyces pombe [Reaction:R-SPO-5627775] Autophosphorylation of PAK1,2,3 - Schizosaccharomyces pombe [Reaction:R-SPO-5627775] Autophosphorylation of PAK1,2,3 - Schizosaccharomyces pombe
schemaClass	Complex
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-182921
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[BlackBoxEvent:R-SPO-9692800] CDC42 translocates to the endoplasmic reticulum membrane [Reaction:R-SPO-9013161] CDC42 GAPs stimulate CDC42 GTPase activity [Reaction:R-SPO-5626469] GTP-bound RAC1 and CDC42 bind IQGAPs [Reaction:R-SPO-389788] Activation of PAKs by RAC1 and CDC42 [Reaction:R-SPO-8981931] RAC1 and CDC42 activate PAK2 [Reaction:R-SPO-8981926] RAC1 and CDC42 activate PAK3 [Reaction:R-SPO-2029456] RAC1 and CDC42 activate PAK1
(output)	[Reaction:R-SPO-9013159] CDC42 GEFs activate CDC42 [Reaction:R-SPO-2029454] Autophosphorylation of PAK1 [Reaction:R-SPO-5627775] Autophosphorylation of PAK1,2,3
(hasComponent)	[Complex:R-SPO-5672334] RAC1,CDC42:GTP:IQGAP1 [plasma membrane] [Complex:R-SPO-5626465] RAC1,CDC42:GTP:IQGAPs [plasma membrane] [Complex:R-SPO-389782] PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] [Complex:R-SPO-8981927] CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] [Complex:R-SPO-8981928] CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] [Complex:R-SPO-2029159] RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane]
(inferredTo)	[Complex:R-HSA-449518] CDC42:GTP [plasma membrane] [DefinedSet:R-HSA-389778] CDC42:GTP, RAC1:GTP [plasma membrane] [Complex:R-HSA-182921] CDC42:GTP [plasma membrane]

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