Reactome | PSMG1 [cytosol]

PSMG1 [cytosol]

Stable Identifier

R-HSA-9908050

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Proteasome assembly chaperone 1, PSMG1_HUMAN, PAC1, Yeast Pba1 ortholog

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O95456 PSMG1

Gene Names

PSMG1, C21LRP, DSCR2, PAC1

Chain

initiator methionine:, chain:2-288

Reference Genes

BioGPS Gene:8624 PSMG1

COSMIC (genes):PSMG1 PSMG1

CTD Gene:8624 PSMG1

dbSNP Gene:8624 PSMG1

ENSEMBL:ENSG00000183527 PSMG1

HGNC:3043 PSMG1

KEGG:hsa:8624 PSMG1

Monarch:8624 PSMG1

NCBI Gene:8624 PSMG1

OMIM:605296 PSMG1

UCSC:O95456 PSMG1

Reference Transcript

Other Identifiers

11717856_a_at

16925674

203405_PM_at

203405_at

36088_at

3932132

3932133

3932135

3932136

3932137

3932138

3932139

3932140

3932141

3932142

3932143

3932144

3932145

8070330

8624

A_23_P68717

GE55798

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005783

GO:0005794

GO:0005829

GO:0021930

GO:0043226

GO:0043248

GO:0051131

GO:0060090

GO:0065003

GO:0070628

GO:0080129

GO:0101031

HMNXSV003016749

ILMN_1659285

ILMN_1779264

PH_hs_0000529

TC21000458.hg

g4505022_3p_at

Participates

as an input of

PSMG1 binds PSMG2 (Homo sapiens)

as a component of

PSMG1:PSMG2 [cytosol] (Homo sapiens)

Inferred To

PSMG1 [cytosol] (Bos taurus)

PSMG1 [cytosol] (Drosophila melanogaster)

PSMG1 [cytosol] (Gallus gallus)

PSMG1 [cytosol] (Sus scrofa)

Psmg1 [cytosol] (Mus musculus)

Psmg1 [cytosol] (Rattus norvegicus)

psmg1 [cytosol] (Danio rerio)

psmg1 [cytosol] (Xenopus tropicalis)

Ghost homologue of PSMG1 [cytosol] (Caenorhabditis elegans)

Ghost homologue of PSMG1 [cytosol] (Canis familiaris)

Ghost homologue of PSMG1 [cytosol] (Plasmodium falciparum)

Ghost homologue of PSMG1 [cytosol] (Saccharomyces cerevisiae)

Ghost homologue of PSMG1 [cytosol] (Schizosaccharomyces pombe)

psmG1 [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_982257.1, NP_003711.1

OpenTargets

ENSG00000183527

ENSEMBL

ENSG00000183527, ENST00000331573, ENSP00000370286, ENSP00000329915, ENST00000380900

HPA

ENSG00000183527-PSMG1

GeneCards

PSMG1

PRO

O95456

Pharos - Targets

O95456

GlyGen

O95456

PDB

8QYM, 8QYS, 8TM3, 8TM4, 8QZ9, 8TM5, 8QYN, 8QYL, 8TM6, 8QYJ

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q969U7 PSMG2	1	PSMG2 [cytosol] (R-HSA-9908053)	0.847	12
UniProt:Q99436 PSMB7	7	PSMB7 [cytosol] (R-HSA-68759) PSMB7 [nucleoplasm] (R-HSA-174331) pro-PSMB7 [cytosol] (R-HSA-9908145) PSMB7(1-43) [cytosol] (R-HSA-9908129) PSMB7 [ficolin-1-rich granule lumen] (R-HSA-6803312) PSMB7 [extracellular region] (R-HSA-6806449) PSMB7 [secretory granule lumen] (R-HSA-6803279)	0.725	6
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.671	7
UniProt:Q9Y244 POMP	1	POMP [cytosol] (R-HSA-9908067)	0.657	4
UniProt:P28066 PSMA5	5	PSMA5 [cytosol] (R-HSA-68732) PSMA5 [nucleoplasm] (R-HSA-174340) PSMA5 [ficolin-1-rich granule lumen] (R-HSA-6803328) PSMA5 [extracellular region] (R-HSA-6806459) PSMA5 [secretory granule lumen] (R-HSA-6803316)	0.643	6
UniProt:P31321 PRKAR1B	2	PRKAR1B [cytosol] (R-HSA-57838) PRKAR1B [ciliary base] (R-HSA-5610409)	0.556	3
UniProt:P25787 PSMA2	5	PSMA2 [cytosol] (R-HSA-68726) PSMA2 [nucleoplasm] (R-HSA-174345) PSMA2 [ficolin-1-rich granule lumen] (R-HSA-6803285) PSMA2 [extracellular region] (R-HSA-6806506) PSMA2 [secretory granule lumen] (R-HSA-6803329)	0.527	4
UniProt:P49721 PSMB2	2	PSMB2 [cytosol] (R-HSA-68744) PSMB2 [nucleoplasm] (R-HSA-174335)	0.527	3
UniProt:Q9NS85 CAH10			0.527	2
UniProt:P49720 PSMB3	2	PSMB3 [cytosol] (R-HSA-68747) PSMB3 [nucleoplasm] (R-HSA-174341)	0.527	4
UniProt:Q9BSU1 PHAF1			0.527	2
UniProt:P28065 PSMB9	3	PSMB9 [cytosol] (R-HSA-68765) pro-PSMB9 [cytosol] (R-HSA-9908136) PSMB9(1-20) [cytosol] (R-HSA-9908132)	0.527	4
UniProt:O14818 PSMA7	2	PSMA7 [cytosol] (R-HSA-68736) PSMA7 [nucleoplasm] (R-HSA-174351)	0.527	2
UniProt:P20618 PSMB1	7	PSMB1 [cytosol] (R-HSA-68738) PSMB1 [nucleoplasm] (R-HSA-174347) pro-PSMB1 [cytosol] (R-HSA-9908139) PSMB1(1-28) [cytosol] (R-HSA-9908143) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340) PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [secretory granule lumen] (R-HSA-6803287)	0.527	4

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