Reactome | PSMG2 [cytosol]

PSMG2 [cytosol]

Stable Identifier

R-HSA-9908053

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Proteasome assembly chaperone 2, PSMG2_HUMAN, PAC2, Yeast Pba2 ortholog

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q969U7 PSMG2

Gene Names

PSMG2, HCCA3, PAC2, TNFSF5IP1

Chain

chain:1-264

Reference Genes

BioGPS Gene:56984 PSMG2

COSMIC (genes):PSMG2 PSMG2

CTD Gene:56984 PSMG2

dbSNP Gene:56984 PSMG2

ENSEMBL:ENSG00000128789 PSMG2

HGNC:24929 PSMG2

KEGG:hsa:56984 PSMG2

Monarch:56984 PSMG2

NCBI Gene:56984 PSMG2

OMIM:609702 PSMG2

UCSC:Q969U7 PSMG2

Reference Transcript

Other Identifiers

11718507_a_at

16851104

16851108

218467_PM_at

218467_at

3655406

3779685

3779686

3779687

3779688

3779690

3779693

3779694

3779695

3779696

3779697

3779698

3779700

3779701

3779703

3779704

3779705

3779706

3779707

3779708

3779709

3779710

3779711

3779712

3779713

3779714

3779715

56984

64113_at

80187_r_at

8020241

A_14_P113466

A_14_P127660

A_23_P118909

A_24_P399362

A_33_P3357653

GE54607

GO:0005515

GO:0005634

GO:0005829

GO:0007094

GO:0043066

GO:0043226

GO:0043248

GO:0051131

GO:0051726

GO:0060090

GO:0065003

GO:0101031

HMNXSV003043750

HMNXSV003045655

ILMN_2088410

PH_hs_0024404

PH_hs_0035884

TC18001006.hg

TC18001007.hg

g9910421_3p_at

g9910421_3p_s_at

p33479

p7915

Participates

as an input of

PSMG1 binds PSMG2 (Homo sapiens)

as a component of

PSMG1:PSMG2 [cytosol] (Homo sapiens)

Inferred To

PSMG2 [cytosol] (Bos taurus)

PSMG2 [cytosol] (Canis familiaris)

PSMG2 [cytosol] (Gallus gallus)

PSMG2 [cytosol] (Sus scrofa)

Psmg2 [cytosol] (Mus musculus)

Psmg2 [cytosol] (Rattus norvegicus)

psmg2 [cytosol] (Danio rerio)

psmg2 [cytosol] (Xenopus tropicalis)

ADD66 [cytosol] (Saccharomyces cerevisiae)

psmG2 [cytosol] (Dictyostelium discoideum)

Dmel\CG12321 [cytosol] (Drosophila melanogaster)

Ghost homologue of PSMG2 [cytosol] (Caenorhabditis elegans)

Ghost homologue of PSMG2 [cytosol] (Plasmodium falciparum)

Ghost homologue of PSMG2 [cytosol] (Schizosaccharomyces pombe)

Cross References

OpenTargets

ENSG00000128789

ENSEMBL

ENSP00000476763, ENST00000699164, ENSG00000128789, ENSP00000325919, ENST00000317615, ENSP00000514171, ENST00000585331

HPA

ENSG00000128789-PSMG2

GeneCards

PSMG2

PRO

Q969U7

Pharos - Targets

Q969U7

GlyGen

Q969U7

PDB

8TM5, 8QYJ, 8QZ9, 8TM4, 8QYM, 8QYS, 8QYL, 8QYN, 8TM6, 8TM3

Interactors (28)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95456 PSMG1	1	PSMG1 [cytosol] (R-HSA-9908050)	0.801	11
UniProt:Q9Y244 POMP	1	POMP [cytosol] (R-HSA-9908067)	0.725	5
UniProt:Q15323 KRT31	1	KRT31 [cytosol] (R-HSA-6809616)	0.718	6
UniProt:Q9BT73 PSMG3	1	PSMG3 [cytosol] (R-HSA-9908033)	0.643	5
UniProt:Q5JS54 PSMG4	1	PSMG4 [cytosol] (R-HSA-9908036)	0.643	4
UniProt:P28065 PSMB9	3	PSMB9 [cytosol] (R-HSA-68765) pro-PSMB9 [cytosol] (R-HSA-9908136) PSMB9(1-20) [cytosol] (R-HSA-9908132)	0.643	5
UniProt:P20618 PSMB1	7	PSMB1 [cytosol] (R-HSA-68738) PSMB1 [nucleoplasm] (R-HSA-174347) pro-PSMB1 [cytosol] (R-HSA-9908139) PSMB1(1-28) [cytosol] (R-HSA-9908143) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340) PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [secretory granule lumen] (R-HSA-6803287)	0.643	4
UniProt:Q06323 PSME1	1	PSME1 [cytosol] (R-HSA-68812)	0.643	3
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.569	7
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:P15884 TCF4	1	TCF4 [nucleoplasm] (R-HSA-445672)	0.556	3
UniProt:P25789 PSMA4	2	PSMA4 [cytosol] (R-HSA-68730) PSMA4 [nucleoplasm] (R-HSA-174324)	0.527	3
UniProt:P49720 PSMB3	2	PSMB3 [cytosol] (R-HSA-68747) PSMB3 [nucleoplasm] (R-HSA-174341)	0.527	4
UniProt:P25787 PSMA2	5	PSMA2 [cytosol] (R-HSA-68726) PSMA2 [nucleoplasm] (R-HSA-174345) PSMA2 [ficolin-1-rich granule lumen] (R-HSA-6803285) PSMA2 [extracellular region] (R-HSA-6806506) PSMA2 [secretory granule lumen] (R-HSA-6803329)	0.527	4
UniProt:Q9BRX9 WDR83	1	WDR83 [endosome membrane] (R-HSA-5672942)	0.527	2
UniProt:P28066 PSMA5	5	PSMA5 [cytosol] (R-HSA-68732) PSMA5 [nucleoplasm] (R-HSA-174340) PSMA5 [ficolin-1-rich granule lumen] (R-HSA-6803328) PSMA5 [extracellular region] (R-HSA-6806459) PSMA5 [secretory granule lumen] (R-HSA-6803316)	0.527	4
UniProt:Q9NQ35 NRIP3			0.527	2
UniProt:Q6PJQ5 FOXR2			0.527	2
UniProt:Q92530 PSMF1	1	PSMF1 [cytosol] (R-HSA-68818)	0.527	3
UniProt:Q8WTP9 XAGE3			0.527	2
UniProt:Q9BQB4 SOST	1	SOST [extracellular region] (R-HSA-3769322)	0.527	2
UniProt:P49721 PSMB2	2	PSMB2 [cytosol] (R-HSA-68744) PSMB2 [nucleoplasm] (R-HSA-174335)	0.527	3
UniProt:Q9NS85 CAH10			0.527	2
UniProt:Q6RVD6 SPAT8			0.527	2
UniProt:Q9Y3I1 FBXO7	1	FBXO7 [cytosol] (R-HSA-8862627)	0.527	2
UniProt:Q99436 PSMB7	7	PSMB7 [cytosol] (R-HSA-68759) PSMB7 [nucleoplasm] (R-HSA-174331) pro-PSMB7 [cytosol] (R-HSA-9908145) PSMB7(1-43) [cytosol] (R-HSA-9908129) PSMB7 [ficolin-1-rich granule lumen] (R-HSA-6803312) PSMB7 [extracellular region] (R-HSA-6806449) PSMB7 [secretory granule lumen] (R-HSA-6803279)	0.527	3
UniProt:O14818 PSMA7	2	PSMA7 [cytosol] (R-HSA-68736) PSMA7 [nucleoplasm] (R-HSA-174351)	0.527	3
UniProt:P28070 PSMB4	4	PSMB4 [cytosol] (R-HSA-68750) PSMB4 [nucleoplasm] (R-HSA-174343) pro-PSMB4 [cytosol] (R-HSA-9908138) PSMB4(1-45) [cytosol] (R-HSA-9908122)	0.527	3

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