CLIP1(1-1083)-LTK(488-864) fusion [plasma membrane]

Stable Identifier
R-HSA-9842572
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
CAP-Gly domain-containing linker protein 1, CLIP1_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
34819663 The CLIP1-LTK fusion is an oncogenic driverĀ in non-small-cell lung cancer

Ikeda, T, Nakachi, I, Watanabe, K, Kodani, M, Hayashi, K, Sakakibara-Konishi, J, Shibata, Y, Nishino, K, Izumi, H, Okamoto, I, Kirita, K, Goto, K, Nosaki, K, Yoh, K, Niho, S, Ishii, G, Matsumoto, S, Kuyama, S, Sakai, T, Liu, J, Furuya, N, Sugiyama, E, Nakai, T, Tanaka, K, Kumagai, S, Yamasaki, A, Daga, H, Zenke, Y, Taima, K, Ebi, N, Hayashida, T, Kato, T, Fukuhara, T, Mori, S, Kobayashi, SS, Udagawa, H, Ohtsu, A, Nakamura, A

Nature 2021
External Reference Information
External Reference
Gene Names
CLIP1, CYLN1, RSN
Chain
chain:1-1438
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 488 to 864 at 1084 from UniProt:P29376 LTK
Coordinate
1084
Disease
Name Identifier Synonyms
non-small cell lung carcinoma DOID:3908 Non-small cell lung cancer (disorder), NSCLC, NSCLC
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Interactors (6)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q15691 MAPRE1  1 0.751 4
 UniProt:P68366 TUBA4A  9 0.618 3
 UniProt:Q14203 DCTN1  7 0.595 3
 UniProt:Q04864-2 REL      0.556 3
 UniProt:P0DTC6 6  4 0.547 2
 UniProt:P13569 CFTR  17 0.483 4
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