Reactome | BCAS2 [nucleoplasm]

BCAS2 [nucleoplasm]

Stable Identifier

R-HSA-5420902

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Pre-mRNA-splicing factor SPF27, SPF27_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O75934 BCAS2

Gene Names

BCAS2, DAM1

Chain

initiator methionine:1, chain:2-225

Reference Genes

BioGPS Gene:10286 BCAS2

COSMIC (genes):BCAS2 BCAS2

CTD Gene:10286 BCAS2

dbSNP Gene:10286 BCAS2

ENSEMBL:ENSG00000116752 BCAS2

HGNC:975 BCAS2

KEGG Gene (Homo sapiens):10286 BCAS2

Monarch:10286 BCAS2

NCBI Gene:10286 BCAS2

OMIM:605783 BCAS2

UCSC:O75934 BCAS2

Reference Transcript

RefSeq:NM_005872.2 BCAS2

Other Identifiers

0002230093

10286

11742764_at

16691204

203053_at

2425292

2429165

2429166

2429167

2429168

2429169

2429170

2429172

2429173

2429176

2429178

2429179

2429180

2692163

34286_at

7918759

A_23_P34930

GE53520

GO:0000228

GO:0000375

GO:0000398

GO:0000974

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005662

GO:0005681

GO:0005694

GO:0005730

GO:0005813

GO:0005815

GO:0005856

GO:0006397

GO:0008150

GO:0008380

GO:0016607

GO:0032991

GO:0034641

GO:0043226

GO:0071007

GO:0071013

HMNXSV003044243

ILMN_1751760

ILMN_2148452

PH_hs_0031073

TC01006365.hg

g5031652_3p_at

Participates

as a component of

PRP19-CDC5L complex [nucleoplasm] (Homo sapiens)

Inferred To

cwf7 [nucleoplasm] (Schizosaccharomyces pombe)

spf27 [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of BCAS2 [nucleoplasm] (Sus scrofa)

Bcas2 [nucleoplasm] (Mus musculus)

Bcas2 [nucleoplasm] (Rattus norvegicus)

BCAS2 [nucleoplasm] (Canis familiaris)

BCAS2 [nucleoplasm] (Drosophila melanogaster)

BCAS2 [nucleoplasm] (Gallus gallus)

BCAS2 [nucleoplasm] (Xenopus tropicalis)

bcas-2 [nucleoplasm] (Caenorhabditis elegans)

bcas2 [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_005863.1

OpenTargets

ENSG00000116752

GeneCards

O75934

HPA

ENSG00000116752-BCAS2

Ensembl

ENST00000369541, ENSG00000116752, ENSP00000358554

PRO

O75934

Pharos - Targets

O75934

GlyGen

O75934

PDB

6ID0, 7A5P, 5MQF, 5Z56, 6QDV, 6ID1, 5Z57, 6ICZ, 5XJC, 6FF7, 5YZG

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08379 GOLGA2	3	GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764) p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179)	0.841	9
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.666	4
UniProt:Q99757 TXN2	3	2xHC-TXN2 [mitochondrial matrix] (R-HSA-3323059) TXN2 [mitochondrial matrix] (R-HSA-3323048) HC-TXN2 [mitochondrial matrix] (R-HSA-9035482)	0.556	3
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.556	3
UniProt:Q02548 PAX5	1	PAX5 [nucleoplasm] (R-HSA-158583)	0.556	3
UniProt:Q13077 TRAF1	3	TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204) TRAF1 [cytosol] (R-HSA-5634163)	0.488	2