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CRNKL1 [nucleoplasm]
Stable Identifier
R-HSA-8867899
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Crooked neck-like protein 1, CRNL1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)
Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C* complex (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
CRNKL1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BZJ0 CRNKL1
Gene Names
CRNKL1, CRN, CGI-201, MSTP021
Chain
initiator methionine:, chain:1-848
Reference Genes
BioGPS Gene:51340 CRNKL1
COSMIC (genes):CRNKL1 CRNKL1
CTD Gene:51340 CRNKL1
dbSNP Gene:51340 CRNKL1
ENSEMBL:ENSG00000101343 CRNKL1
ENSEMBL_homo_sapiens_GENE:ENSG00000101343.15 CRNKL1
HGNC:15762 CRNKL1
KEGG Gene (Homo sapiens):51340 CRNKL1
Monarch:51340 CRNKL1
NCBI Gene:51340 CRNKL1
OMIM:610952 CRNKL1
UCSC:Q9BZJ0 CRNKL1
Reference Transcript
RefSeq:NM_001278626.1 CRNKL1
RefSeq:NM_016652.5 CRNKL1
RefSeq:NM_001278628.1 CRNKL1
RefSeq:NM_001278625.1 CRNKL1
RefSeq:NM_001278627.1 CRNKL1
Other Identifiers
11730749_a_at
11730750_a_at
11730751_s_at
11745076_a_at
11745077_a_at
16917655
219913_PM_s_at
219913_s_at
3899948
3899950
3899951
3899953
3899955
3899956
3899957
3899958
3899959
3899960
3899961
3899964
3899966
3899968
3899969
3899970
3899971
3899972
3899975
3899976
3899977
3899979
3899980
3899981
3899982
3899983
3899984
3899985
3899986
3899987
3899988
3899989
3899990
3899991
51340
65609_at
77990_at
8065256
A_23_P131967
A_24_P40229
GE653978
GE88121
GO:0000245
GO:0000398
GO:0000974
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0006396
GO:0006397
GO:0008380
GO:0016071
GO:0016607
GO:0043226
GO:0065003
GO:0071007
GO:0071013
GO:0071014
HMNXSV003022171
ILMN_1768640
PH_hs_0022832
TC20000681.hg
g11072090_3p_a_at
Participates
as a component of
Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
PRP19-CDC5L related complex [nucleoplasm] (Homo sapiens)
Inferred To
crn [nucleoplasm]
(Drosophila melanogaster)
cwf4 [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of CRNKL1 [nucleoplasm]
(Xenopus tropicalis)
syf-3 [nucleoplasm]
(Caenorhabditis elegans)
crnkl1 [nucleoplasm]
(Danio rerio)
crnkl1 [nucleoplasm]
(Dictyostelium discoideum)
CRNKL1 [nucleoplasm]
(Bos taurus)
CRNKL1 [nucleoplasm]
(Canis familiaris)
CRNKL1 [nucleoplasm]
(Gallus gallus)
CRNKL1 [nucleoplasm]
(Plasmodium falciparum)
CRNKL1 [nucleoplasm]
(Sus scrofa)
Crnkl1 [nucleoplasm]
(Mus musculus)
Crnkl1 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_001265555.1
,
NP_001265556.1
,
NP_001265557.1
,
NP_057736.4
,
NP_001265554.1
OpenTargets
ENSG00000101343
HPA
ENSG00000101343-CRNKL1
GeneCards
Q9BZJ0
Ensembl
ENSG00000101343
,
ENST00000496549
,
ENSP00000440733
,
ENSP00000366557
,
ENST00000377340
,
ENSP00000428436
,
ENST00000536226
PRO
Q9BZJ0
Pharos - Targets
Q9BZJ0
PDB
7QTT
,
7W5B
,
5Z58
,
6QDV
,
6FF7
,
7A5P
,
5XJC
,
7DVQ
,
6ID0
,
8C6J
,
7ABI
,
8CH6
,
5Z56
,
6ID1
,
6ZYM
,
5MQF
,
6ICZ
,
7W59
,
5Z57
,
6FF4
,
7W5A
,
5YZG
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8WUD4 CCDC12
1
CCDC12 [nucleoplasm]
(R-HSA-9769561)
0.632
4
UniProt:P14678 SNRPB
4
SNRPB [nucleoplasm]
(R-HSA-71896)
Me2-R108,R112-SNRPB [nucleoplasm]
(R-HSA-192213)
SNRPB [cytosol]
(R-HSA-191798)
2xMe-SNRPB [cytosol]
(R-HSA-192218)
0.527
2
UniProt:P62306 SNRPF
2
SNRPF [nucleoplasm]
(R-HSA-71907)
SNRPF [cytosol]
(R-HSA-191852)
0.527
3
UniProt:P07910 HNRNPC
3
HNRNPC [cytosol]
(R-HSA-9715136)
SUMO1-K250-HNRNPC [nucleoplasm]
(R-HSA-4570543)
HNRNPC [nucleoplasm]
(R-HSA-71933)
0.483
2
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