GSDME(1-270) E177V [cytosol]

Stable Identifier
R-HSA-9710403
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Gasdermin-E (1-270) E177V, Gasdermin-E, N-terminal
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
32188940 Gasdermin E suppresses tumour growth by activating anti-tumour immunity

Zhang, Z, Zhang, Y, Xia, S, Kong, Q, Li, S, Liu, X, Junqueira, C, Meza-Sosa, KF, Mok, TMY, Ansara, J, Sengupta, S, Yao, Y, Wu, H, Lieberman, J

Nature 2020
External Reference Information
External Reference
Gene Names
GSDME, DFNA5, ICERE1
Chain
chain:1-496, chain:1-270, chain:271-496
Other Identifiers
0006550050
11719194_a_at
1687
17055910
203695_s_at
3041817
3041818
3041819
3041820
3041826
3041828
3041829
3041835
3041836
3041837
3041844
3041847
3041848
3041849
3041860
3041861
3041864
3041865
3041866
41872_at
8138602
A_23_P82449
A_33_P3221293
GE54686
GO:0003674
GO:0005515
GO:0005546
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0005886
GO:0006464
GO:0007165
GO:0007605
GO:0008150
GO:0008219
GO:0008283
GO:0008285
GO:0008289
GO:0012501
GO:0016020
GO:0016021
GO:0030154
GO:0043167
GO:0043410
GO:0048856
GO:0050877
GO:0060113
GO:0070265
GO:0070269
GO:0071356
GO:0098586
GO:1901612
GO:2001244
HMNXSV003001929
HMNXSV003019197
ILMN_1670145
PH_hs_0023638
g4758153_3p_a_at
Participates
Other forms of this molecule
Modified Residues
Name
L-glutamic acid 177 replaced with L-valine
Coordinate
177
PsiMod
A protein modification that effectively removes or replaces an L-glutamic acid.
A protein modification that effectively converts a source amino acid residue to an L-valine.
Disease
Name Identifier Synonyms
head and neck squamous cell carcinoma DOID:5520 carcinoma of the head and neck, squamous cell carcinoma of the head and neck
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96CG3 TIFA  2 0.556 3
Cite Us!