Reactome | GSDME (271-496) [cytosol]

GSDME (271-496) [cytosol]

Stable Identifier

R-HSA-9647615

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Gasdermin-E (271-496), Gasdermin-E, C-terminal

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O60443 GSDME

Gene Names

GSDME, DFNA5, ICERE1

Chain

chain:1-496, chain:1-270, chain:271-496

Reference Genes

BioGPS Gene:1687 GSDME

COSMIC (genes):GSDME GSDME

CTD Gene:1687 GSDME

dbSNP Gene:1687 GSDME

ENSEMBL:ENSG00000105928.16 GSDME

HGNC:2810 GSDME

KEGG Gene (Homo sapiens):1687 GSDME

Monarch:1687 GSDME

NCBI Gene:1687 GSDME

OMIM:608798 GSDME

UCSC:O60443 GSDME

Reference Transcript

Other Identifiers

11719194_a_at

1687

17055910

203695_PM_s_at

203695_s_at

3041817

3041818

3041819

3041820

3041826

3041828

3041829

3041835

3041836

3041837

3041844

3041847

3041848

3041849

3041860

3041861

3041864

3041865

3041866

41872_at

8138602

A_23_P82449

A_33_P3221293

GE54686

GO:0005515

GO:0005546

GO:0005737

GO:0005829

GO:0005886

GO:0007605

GO:0008219

GO:0008285

GO:0008289

GO:0012501

GO:0016020

GO:0023052

GO:0030154

GO:0042491

GO:0043410

GO:0048856

GO:0050877

GO:0070265

GO:0070269

GO:0071356

GO:0098586

GO:1901612

GO:2001244

HMNXSV003001929

HMNXSV003019197

ILMN_1670145

PH_hs_0023638

g4758153_3p_a_at

Participates

as an output of

Other forms of this molecule

GSDME(1-270) G199E [cytosol]

GSDME(1-270) R48I [cytosol]

GSDME(1-270) I137T [cytosol]

GSDME W46* [cytosol]

GSDME(1-270) D18V [cytosol]

GSDME(1-270) D14Y [cytosol]

GSDME(1-270) P212L [cytosol]

GSDME(1-270) W44C [cytosol]

GSDME(1-270) I217N [cytosol]

GSDME E210* [cytosol]

GSDME(1-270) [cytosol]

GSDME [cytosol]

GSDME(1-270) E177V [cytosol]

GSDME(1-270) T196M [cytosol]

GSDME(1-270) G17D [cytosol]

GSDME(1-270) E134A [cytosol]

GSDME(1-270) N24D [cytosol]

Inferred To

GSDME (271-496) [cytosol] (Canis familiaris)

GSDME (271-496) [cytosol] (Gallus gallus)

GSDME [cytosol] (Bos taurus)

GSDME [cytosol] (Sus scrofa)

dfna5 [cytosol] (Danio rerio)

Gsdme [cytosol] (Mus musculus)

Gsdme [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_004394.1, XP_016867291.1, NP_001120925.1, NP_001120926.1

OpenTargets

ENSG00000105928

HPA

ENSG00000105928-GSDME

GeneCards

O60443

Ensembl

ENST00000645220, ENST00000342947, ENST00000409970, ENSP00000494186, ENSP00000401332, ENST00000419307, ENSP00000339587, ENSG00000105928, ENSP00000387119

PRO

O60443

Pharos - Targets

O60443

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96CG3 TIFA	2	TIFA [cytosol] (R-HSA-451582) p-T9-TIFA [cytosol] (R-HSA-9645512)	0.556	3

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