p-8Y-FGFR2b C382R [plasma membrane]

Stable Identifier
R-HSA-9667344
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
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General
also Apert
External Reference Information
External Reference
UniProt:P21802-3 FGFR2
Gene Names
FGFR2, BEK, KGFR, KSAM
Participates
as a component of
Other forms of this molecule
p-8Y-FGFR2-3 [plasma membrane]
FGFR2b long [plasma membrane]
p-8Y-FGFR2b S376C [plasma membrane]
p-8Y-FGFR2b S373C [plasma membrane]
p-8Y-FGFR2b P253R [plasma membrane]
p-8Y-FGFR2b S252W [plasma membrane]
FGFR2b Y376C [plasma membrane]
FGFR2b C382R [plasma membrane]
FGFR2b S373C [plasma membrane]
FGFR2b P253R [plasma membrane]
FGFR2b S252W [plasma membrane]
Modified Residues
Name
O4'-phospho-L-tyrosine at 467
Coordinate
467
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 587
Coordinate
587
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 589
Coordinate
589
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 657
Coordinate
657
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 658
Coordinate
658
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 734
Coordinate
734
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 770
Coordinate
770
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 780
Coordinate
780
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
L-cysteine 382 replaced with L-arginine
Coordinate
382
PsiMod
L-cysteine removal [MOD:01635]
A protein modification that effectively removes or replaces an L-cysteine.
L-arginine residue [MOD:00011]
A protein modification that effectively converts a source amino acid residue to an L-arginine.
Disease
Name Identifier Synonyms
endometrial cancer DOID:1380 primary malignant neoplasm of endometrium, neoplasm of endometrium (disorder), endometrial neoplasm, malignant endometrial neoplasm, endometrial Ca, malignant neoplasm of endometrium, tumor of Endometrium
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
Mondo
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
COSMIC
IntEnz
GeneCards
HPA
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (31)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P09038 FGF2  1 0.779 5
 UniProt:P51812 RPS6KA3  7 0.745 5
 UniProt:P62993 GRB2  1 0.735 6
 ChEBI:73280 SSR      0.683 8
 UniProt:P05230 FGF1  1 0.675 3
 UniProt:P11362 FGFR1  9 0.623 3
 UniProt:O15520 FGF10  1 0.571 2
 UniProt:P06734 FCER2  1 0.558 2
 UniProt:P19174 PLCG1  6 0.528 3
 UniProt:Q3MIR4 CC50B      0.527 2
 UniProt:O60637 TSN3      0.527 2
 UniProt:Q96LL9 DJC30      0.527 2
 UniProt:Q6P047 CH074      0.527 2
 UniProt:Q99732 LITAF      0.527 2
 UniProt:Q8N7X8 SIGL1      0.527 2
 UniProt:Q5T9A4 ATAD3B  3 0.527 2
 UniProt:Q96HB5 CC120      0.527 2
 UniProt:Q8IWX8 CHERP  1 0.527 2
 UniProt:Q92551 IP6K1  2 0.527 2
 UniProt:Q6P995 F171B      0.527 2
 UniProt:P34741 SDC2  20 0.527 2
 UniProt:Q92575 UBXN4      0.527 2
 UniProt:Q96L94 SNX22      0.527 2
 UniProt:P01033 TIMP1  4 0.527 2
 UniProt:Q96G30 MRAP2      0.527 2
 UniProt:P55899 FCGRN      0.527 2
 UniProt:Q5TF58 IFFO2      0.527 2
 UniProt:Q06124 PTPN11  4 0.519 2
 UniProt:Q9ULH0 KIDINS220  2 0.483 2
 UniProt:Q9UBH6 S53A1      0.483 2
 UniProt:Q86VI4 LAP4B      0.463 2
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