Reactome | CAPZA2(265-276) [extracellular region]

CAPZA2(265-276) [extracellular region]

Stable Identifier

R-HSA-879417

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

F-actin-capping protein subunit alpha-2 fragment TRTK-12, CAPZA2, CAZA2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P47755 CAPZA2

Gene Names

CAPZA2

Chain

initiator methionine:, chain:2-286

Reference Genes

BioGPS Gene:830 CAPZA2

COSMIC (genes):CAPZA2 CAPZA2

CTD Gene:830 CAPZA2

dbSNP Gene:830 CAPZA2

ENSEMBL:ENSG00000198898 CAPZA2

ENSEMBL_homo_sapiens_GENE:ENSG00000198898.16 CAPZA2

HGNC:1490 CAPZA2

KEGG Gene (Homo sapiens):830 CAPZA2

Monarch:830 CAPZA2

NCBI Gene:830 CAPZA2

OMIM:601571 CAPZA2

UCSC:P47755 CAPZA2

Reference Transcript

RefSeq:NM_006136.2 CAPZA2

Other Identifiers

11723011_s_at

11723012_a_at

11723013_x_at

11747046_x_at

11750192_x_at

17050622

201237_PM_at

201237_at

201238_PM_s_at

201238_s_at

3020446

3020447

3020464

3020468

3020471

3020473

3020475

3020480

3020481

3020484

3020486

3020487

3020488

3020489

3020491

3638241

3638244

36641_at

8135625

830

A_14_P108438

A_23_P307940

GE58868

GE79906

GE86004

GO:0003779

GO:0005515

GO:0005576

GO:0005615

GO:0005829

GO:0005856

GO:0005903

GO:0007010

GO:0008092

GO:0008290

GO:0015629

GO:0016020

GO:0030036

GO:0030863

GO:0043226

GO:0051015

GO:0051016

GO:0051693

GO:0065003

GO:0070062

HMNXSV003017687

Hs.75546.0.S3_3p_at

ILMN_1768870

U03851_at

g13529130_3p_a_at

Participates

as a member of

F-actin capping protein alpha protein fragment TRTK-12 [extracellular region] (Homo sapiens)

Other forms of this molecule

CAPZA2 [cytosol]

Inferred To

cap-1 [extracellular region] (Caenorhabditis elegans)

acp1 [extracellular region] (Schizosaccharomyces pombe)

acpB [extracellular region] (Dictyostelium discoideum)

Capza2 [extracellular region] (Mus musculus)

Capza2 [extracellular region] (Rattus norvegicus)

CAP1 [extracellular region] (Saccharomyces cerevisiae)

CAPZA1(265-276) [extracellular region] (Plasmodium falciparum)

capza2 [extracellular region] (Xenopus tropicalis)

CAPZA2 [extracellular region] (Bos taurus)

CAPZA2 [extracellular region] (Canis familiaris)

CAPZA2 [extracellular region] (Gallus gallus)

CAPZA2 [extracellular region] (Sus scrofa)

cpa [extracellular region] (Drosophila melanogaster)

Cross References

RefSeq

NP_006127.1

OpenTargets

ENSG00000198898

GeneCards

P47755

HPA

ENSG00000198898-CAPZA2

Ensembl

ENSG00000198898, ENSP00000354947, ENST00000361183

PRO

P47755

Pharos - Targets

P47755

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96B97 SH3KBP1	3	SH3KBP1 [plasma membrane] (R-HSA-182955) SH3KBP1 [cytosol] (R-HSA-182957) Ub-SH3KBP1 [cytosol] (R-HSA-182926)	0.643	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	15
UniProt:Q9JLQ0 Cd2ap	1	CD2AP_MOUSE [cytosol] (R-MMU-451711)	0.564	2
UniProt:P52907 CAPZA1	2	CAPZA1 [cytosol] (R-HSA-879363) CAPZA1(265-276) [extracellular region] (R-HSA-879421)	0.527	2
UniProt:Q9Y5K6 CD2AP	1	CD2AP [cytosol] (R-HSA-373620)	0.527	2
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.527	5
UniProt:Q14203 DCTN1	7	DCTN1(1-1065)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711969) DCTN1(1-599)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711960) DCTN1(1-1177)-ALK(1058-1620) fusion [cytosol] (R-HSA-9701997) DCTN1(1-1065)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711959) DCTN1(1-599)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711953) DCTN1(1-1177)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711962) DCTN1 [cytosol] (R-HSA-535580)	0.483	2

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