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CD2AP [cytosol]
Stable Identifier
R-HSA-373620
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
CD2-associated protein, CD2AP_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Nephrin family interactions (Homo sapiens)
Nephrin binds CD2AP (Homo sapiens)
CD2AP [cytosol] (Homo sapiens)
CD2AP:p-Nephrin:Fyn:NEPH1 [plasma membrane] (Homo sapiens)
CD2AP [cytosol] (Homo sapiens)
p85 associates with both p-Nephrin and CD2AP (Homo sapiens)
CD2AP:p-Nephrin:Fyn:NEPH1 [plasma membrane] (Homo sapiens)
CD2AP [cytosol] (Homo sapiens)
PI3K:CD2AP:p-Nephrin:Fyn:NEPH1 [plasma membrane] (Homo sapiens)
CD2AP:p-Nephrin:Fyn:NEPH1 [plasma membrane] (Homo sapiens)
CD2AP [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y5K6 CD2AP
Gene Names
CD2AP
Chain
chain:1-639
Reference Genes
BioGPS Gene:23607 CD2AP
COSMIC (genes):CD2AP CD2AP
CTD Gene:23607 CD2AP
dbSNP Gene:23607 CD2AP
ENSEMBL:ENSG00000198087 CD2AP
HGNC:14258 CD2AP
KEGG Gene (Homo sapiens):23607 CD2AP
Monarch:23607 CD2AP
NCBI Gene:23607 CD2AP
OMIM:604241 CD2AP
UCSC:Q9Y5K6 CD2AP
Reference Transcript
RefSeq:NM_012120.2 CD2AP
Other Identifiers
0000050138
11724033_s_at
11724034_at
11724035_at
17009399
203593_at
23607
236257_at
2909403
2909405
2909406
2909407
2909408
2909409
2909415
2909423
2909427
2909432
2909441
2909443
2909444
2909447
2909449
2909450
2909454
2909457
2909465
2909467
2909468
2909469
2909471
2909474
2909475
2909476
2909477
2909478
34699_at
8120102
83120_i_at
83122_r_at
A_14_P132797
A_24_P329152
A_32_P155811
GE79577
GO:0001650
GO:0001726
GO:0003674
GO:0005172
GO:0005198
GO:0005200
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005730
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0005911
GO:0006810
GO:0006930
GO:0007010
GO:0007015
GO:0007049
GO:0007155
GO:0007165
GO:0008013
GO:0008022
GO:0008150
GO:0009056
GO:0015031
GO:0015629
GO:0016050
GO:0016192
GO:0016477
GO:0017124
GO:0022607
GO:0030054
GO:0030139
GO:0031252
GO:0031410
GO:0031941
GO:0032911
GO:0032991
GO:0040011
GO:0042802
GO:0042995
GO:0043161
GO:0043226
GO:0044877
GO:0045296
GO:0048259
GO:0048471
GO:0048870
GO:0050714
GO:0051058
GO:0051301
GO:0065003
GO:0070062
GO:0098609
GO:1900182
GO:2000249
Hs.149111.0.A1_3p_at
ILMN_1730433
PH_hs_0018127
TC06000633.hg
g11321633_3p_at
Participant Of
input
Nephrin binds CD2AP
hasComponent
CD2AP:p-Nephrin:Fyn:NEPH1 [plasma membrane]
Cross References
RefSeq
NP_036252.1
OpenTargets
ENSG00000198087
GeneCards
Q9Y5K6
HPA
ENSG00000198087-CD2AP
Ensembl
ENSG00000198087
,
ENST00000359314
,
ENSP00000352264
PRO
Q9Y5K6
Orphanet
19254
PDB
2J6K
,
4WCI
,
2J6F
,
2J6O
,
3AA6
,
3U23
,
4X1V
,
2J7I
,
3LK4
,
2FEI
Interactors (17)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06729 CD2
1
CD2 [plasma membrane]
(R-HSA-197795)
0.802
6
UniProt:P22681 CBL
39
CBL R420Q [cytosol]
(R-HSA-9706186)
CBL R420G [cytosol]
(R-HSA-9706203)
CBL Y371H [cytosol]
(R-HSA-9706680)
CBL H398Y [cytosol]
(R-HSA-9706639)
CBL P417A [cytosol]
(R-HSA-9706636)
CBL S376F [cytosol]
(R-HSA-9706643)
CBL del366-409 [cytosol]
(R-HSA-9706179)
CBL del366-477 [cytosol]
(R-HSA-9706176)
CBL R499L [cytosol]
(R-HSA-9706678)
CBL L380P [cytosol]
(R-HSA-9706630)
CBL L287R [cytosol]
(R-HSA-9706693)
CBL L380R [cytosol]
(R-HSA-9706635)
CBL G375P [cytosol]
(R-HSA-9706219)
CBL P417L [cytosol]
(R-HSA-9706634)
CBL H398Q [cytosol]
(R-HSA-9706633)
CBL P417R [cytosol]
(R-HSA-9706632)
CBL R499* [cytosol]
(R-HSA-9706670)
CBL H398R [cytosol]
(R-HSA-9706638)
CBL H398P [cytosol]
(R-HSA-9706637)
CBL G375fs*16 [cytosol]
(R-HSA-9706211)
CBL R420* [cytosol]
(R-HSA-9706208)
CBL H398D [cytosol]
(R-HSA-9706631)
CBL Y371C [cytosol]
(R-HSA-9706694)
CBL G375S [cytosol]
(R-HSA-9706214)
CBL Y371D [cytosol]
(R-HSA-9706687)
CBL Y371S [cytosol]
(R-HSA-9706674)
CBL P417S [cytosol]
(R-HSA-9706642)
CBL H398N [cytosol]
(R-HSA-9706641)
CBL R420P [cytosol]
(R-HSA-9706193)
CBL Y371N [cytosol]
(R-HSA-9706679)
CBL R499Q [cytosol]
(R-HSA-9706677)
CBL R420L [cytosol]
(R-HSA-9706197)
CBL P417H [cytosol]
(R-HSA-9706644)
p-Y371-CBL [plasma membrane]
(R-HSA-182923)
p-Y-CBL [cytosol]
(R-HSA-8875457)
p-Y371-CBL [cytosol]
(R-HSA-182940)
PolyUb,p-Y700,Y731,Y774-CBL [cytosol]
(R-HSA-8848826)
p-Y700,Y731,Y774-CBL [cytosol]
(R-HSA-912656)
CBL [cytosol]
(R-HSA-112199)
0.796
7
UniProt:Q13191 CBLB
1
CBLB [cytosol]
(R-HSA-976009)
0.747
11
UniProt:P13127 CAPZA1
3
CAPZA1(265-276) [extracellular region]
(R-GGA-879421)
F-actin-capping protein subunit alpha-1 [cytosol]
(R-GGA-994167)
CAPZA1 [cytosol]
(R-GGA-879363)
0.667
3
UniProt:Q96B97 SH3KBP1
3
SH3KBP1 [cytosol]
(R-HSA-182957)
SH3KBP1 [plasma membrane]
(R-HSA-182955)
Ub-SH3KBP1 [cytosol]
(R-HSA-182926)
0.659
4
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.659
3
UniProt:P06241 FYN
6
MyrG2-PalmC3,6-FYN [plasma membrane]
(R-HSA-9606873)
p-S21,Y420-FYN [cytosol]
(R-HSA-5218745)
p-Y531-FYN [cytosol]
(R-HSA-391819)
p-Y420-FYN [cytosol]
(R-HSA-391821)
FYN [cytosol]
(R-HSA-200917)
MyrG-p-Y420-FYN [plasma membrane]
(R-HSA-1810410)
0.573
2
UniProt:Q8WUM4 PDCD6IP
1
PDCD6IP [cytosol]
(R-HSA-917717)
0.573
3
UniProt:P47753
2
Capza1 [cytosol]
(R-MMU-879363)
Capza1 [extracellular region]
(R-MMU-879421)
0.564
2
UniProt:P46940 IQGAP1
3
IQGAP1 [secretory granule membrane]
(R-HSA-6804803)
IQGAP1 [cytosol]
(R-HSA-5626371)
IQGAP1 [plasma membrane]
(R-HSA-381681)
0.556
4
UniProt:Q9Y5K6 CD2AP
1
CD2AP [cytosol]
(R-HSA-373620)
0.547
3
UniProt:P47755 CAPZA2
2
CAPZA2 [cytosol]
(R-HSA-879448)
CAPZA2(265-276) [extracellular region]
(R-HSA-879417)
0.527
2
UniProt:Q9H0H5 RACGAP1
1
RACGAP1 [cytosol]
(R-HSA-195122)
0.527
2
UniProt:Q99816 TSG101
1
TSG101 [endosome membrane]
(R-HSA-2980549)
0.499
2
UniProt:Q8WV28 BLNK
2
p-5Y-BLNK [plasma membrane]
(R-HSA-983579)
BLNK [cytosol]
(R-HSA-912750)
0.499
2
UniProt:Q68CZ1 RPGRIP1L
1
RPGRIP1L [cytosol]
(R-HSA-5610418)
0.462
2
UniProt:Q9Y2H1 ST38L
0.462
4
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