Reactome | RQCD1 [cytosol]

RQCD1 [cytosol]

Stable Identifier

R-HSA-430029

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Cell differentiation protein RCD1 homolog, RCD1_HUMAN

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
        
        TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Homo sapiens)
        
        BTG2 binds CCR4-NOT complex (Homo sapiens)
        
        BTG2:CCR4-NOT [cytosol] (Homo sapiens)
        
        CCR4-NOT Complex [cytosol] (Homo sapiens)
        
        RQCD1 [cytosol] (Homo sapiens)
        
        CCR4-NOT Complex [cytosol] (Homo sapiens)
        
        RQCD1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q92600 RQCD1

Gene Names

RQCD1, CNOT9, RCD1

Chain

chain:1-299

Reference Genes

BioGPS Gene:9125 CNOT9

COSMIC (genes):CNOT9 RQCD1

CTD Gene:9125 RQCD1

dbSNP Gene:9125 RQCD1

ENSEMBL:ENSG00000144580 RQCD1

HGNC:10445 CNOT9

KEGG:hsa:9125 CNOT9

Monarch:9125 CNOT9

NCBI Gene:9125 CNOT9

OMIM:612054 CNOT9

UCSC:Q92600 CNOT9

Reference Transcript

Participates

as a component of

Other forms of this molecule

RQCD1 [nucleoplasm]

Inferred To

Cnot9 [cytosol] (Rattus norvegicus)

CNOT9 [cytosol] (Bos taurus)

CNOT9 [cytosol] (Canis familiaris)

CNOT9 [cytosol] (Gallus gallus)

CNOT9 [cytosol] (Sus scrofa)

Rqcd1 [cytosol] (Mus musculus)

RQCD1 [cytosol] (Dictyostelium discoideum)

cnot9 [cytosol] (Danio rerio)

cnot9 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001258563.1, NP_001258564.1, NP_005435.1

OpenTargets

ENSG00000144580

ENSEMBL

ENSP00000486540, ENST00000295701, ENSP00000295701, ENST00000273064, ENSP00000273064, ENST00000627282, ENSG00000144580

HPA

ENSG00000144580-CNOT9

GeneCards

CNOT9

PRO

Q92600

Pharos - Targets

Q92600

GlyGen

Q92600

PDB

4CRV, 6HOM, 6HON, 2FV2, 5ONB, 5ONA, 4CT6, 5LSW, 4CT7, 4CRU

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UKZ1 CNOT11	1	CNOT11 [cytosol] (R-HSA-429981)	0.725	5
UniProt:P47756 CAPZB	1	CAPZB [cytosol] (R-HSA-879409)	0.643	4
UniProt:P47755 CAPZA2	2	CAPZA2 [cytosol] (R-HSA-879448) CAPZA2(265-276) [extracellular region] (R-HSA-879417)	0.643	5
UniProt:P50616 TOB1			0.643	4
UniProt:Q8N443 RIBC1			0.643	4
UniProt:Q96LI5 CNOT6L	1	CNOT6L [cytosol] (R-HSA-430027)	0.564	3
UniProt:Q8IYV9 IZUMO1	1	IZUMO1 [plasma membrane] (R-HSA-508399)	0.527	2
UniProt:P09237 MMP7	6	MMP7(95-267) [extracellular region] (R-HSA-1442479) MMP7(18-267) [extracellular region] (R-HSA-1604734) MMP7(18-94) [extracellular region] (R-HSA-1604729) MMP7(51-267) [extracellular region] (R-HSA-1604766) MMP7(18-50) [extracellular region] (R-HSA-1604759) MMP7(51-94) [extracellular region] (R-HSA-1604760)	0.527	3
UniProt:Q9P2S5 WRP73			0.527	2
UniProt:Q96PS1 FACOS			0.527	3
UniProt:Q9BXU3 TX13A			0.527	3
UniProt:Q8N4C8 MINK1	1	MINK1 [cytosol] (R-HSA-2532788)	0.527	2
UniProt:O75293 GA45B			0.527	2
UniProt:O75175 CNOT3	1	CNOT3 [cytosol] (R-HSA-429872)	0.527	3
UniProt:Q9UIV1 CNOT7	1	CNOT7 [cytosol] (R-HSA-429877)	0.527	2
UniProt:P60321 NANO2			0.527	2
UniProt:Q9NZN8 CNOT2	1	CNOT2 [cytosol] (R-HSA-429902)	0.508	2
UniProt:Q60809 Cnot7	1	Cnot7 [cytosol] (R-MMU-9817672)	0.462	2

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