Reactome | SART1 [nucleoplasm]

SART1 [nucleoplasm]

Stable Identifier

R-HSA-4615999

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

U4/U6.U5 tri-snRNP-associated protein 1, SNUT1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43290 SART1

Gene Names

SART1

Chain

chain:1-800

Reference Genes

BioGPS Gene:9092 SART1

COSMIC (genes):SART1 SART1

CTD Gene:9092 SART1

dbSNP Gene:9092 SART1

ENSEMBL:ENSG00000175467 SART1

ENSEMBL_homo_sapiens_GENE:ENSG00000175467.15 SART1

HGNC:10538 SART1

KEGG Gene (Homo sapiens):9092 SART1

Monarch:9092 SART1

NCBI Gene:9092 SART1

OMIM:605941 SART1

UCSC:O43290 SART1

Reference Transcript

RefSeq:NM_005146.4 SART1

Other Identifiers

11724472_at

11748442_a_at

11754994_a_at

11761260_x_at

16727194

18671293

18671294

18671295

18671298

18671299

18671300

18671301

18671302

18671304

18671305

18671306

18671307

18671308

18671309

18671312

18671313

18671314

200051_PM_at

200051_at

3335775

3335776

3335777

3335778

3335779

3335781

3335782

3335783

3335784

3335785

3335786

3335789

3335791

3335792

3335793

3335795

3335796

3335797

3335798

3335799

3335801

3335802

3335803

3335804

33706_at

50455_at

7892670

7893229

7893232

7893413

7893517

7893587

7893714

7893747

7893905

7894146

7894199

7894251

7894435

7894884

7895056

7895187

7895620

7895759

7895841

7896325

7896476

7896677

7941478

9092

A_23_P86884

A_33_P3299435

GE61573

GO:0000387

GO:0000398

GO:0000481

GO:0002376

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005737

GO:0005794

GO:0005829

GO:0006397

GO:0007155

GO:0008380

GO:0015030

GO:0016071

GO:0016607

GO:0030154

GO:0042254

GO:0043226

GO:0045292

GO:0045585

GO:0046540

GO:0048856

GO:0065003

GO:0071005

GO:0071013

HMNXSV003055009

ILMN_1680145

PH_hs_0025263

TC11000649.hg

g10863888_3p_at

Participates

as an output of

Formation of the Spliceosomal B complex (Homo sapiens)

as a component of

U4:U5:U6 tri-snRNP complex [nucleoplasm] (Homo sapiens)

Inferred To

Dmel\CG6686 [nucleoplasm] (Drosophila melanogaster)

Sart1 [nucleoplasm] (Mus musculus)

Sart1 [nucleoplasm] (Rattus norvegicus)

Ghost homologue of SART1 [nucleoplasm] (Gallus gallus)

snu66 [nucleoplasm] (Schizosaccharomyces pombe)

SART1 [nucleoplasm] (Bos taurus)

SART1 [nucleoplasm] (Canis familiaris)

SART1 [nucleoplasm] (Dictyostelium discoideum)

SART1 [nucleoplasm] (Plasmodium falciparum)

SART1 [nucleoplasm] (Sus scrofa)

sart1 [nucleoplasm] (Xenopus tropicalis)

sart-1 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_005137.1

OpenTargets

ENSG00000175467

HPA

ENSG00000175467-SART1

GeneCards

O43290

Ensembl

ENSP00000310448, ENSG00000175467, ENST00000312397

PRO

O43290

Pharos - Targets

O43290

PDB

5O9Z, 6QX9, 6QW6, 8Q7N, 8QO9, 4PYU, 6AHD, 8Y6O

Interactors (24)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43395 PRPF3	1	PRPF3 [nucleoplasm] (R-HSA-6806806)	0.716	7
UniProt:O94906 PRPF6	1	PRPF6 [nucleoplasm] (R-HSA-71881)	0.681	6
UniProt:Q9BZL1 UBL5	1	UBL5 [nucleoplasm] (R-HSA-9770255)	0.667	4
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.632	3
UniProt:Q6P2Q9 PRPF8	1	PRPF8 [nucleoplasm] (R-HSA-83810)	0.564	2
UniProt:Q15428 SF3A2	1	SF3A2 [nucleoplasm] (R-HSA-71964)	0.564	2
UniProt:O75554 WBP4	1	WBP4 [nucleoplasm] (R-HSA-8867895)	0.564	2
UniProt:O75031 HSF2B			0.556	6
UniProt:P14678 SNRPB	4	SNRPB [nucleoplasm] (R-HSA-71896) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [cytosol] (R-HSA-191798) 2xMe-SNRPB [cytosol] (R-HSA-192218)	0.527	2
UniProt:Q9BTD8 RBM42	1	RBM42 [nucleoplasm] (R-HSA-9769526)	0.527	2
UniProt:P62304 SNRPE	2	SNRPE [nucleoplasm] (R-HSA-71905) SNRPE [cytosol] (R-HSA-191782)	0.527	4
UniProt:P62306 SNRPF	2	SNRPF [nucleoplasm] (R-HSA-71907) SNRPF [cytosol] (R-HSA-191852)	0.527	2
UniProt:Q13523 PRPF4B	1	PRPF4B [nucleoplasm] (R-HSA-9769525)	0.527	2
UniProt:O43172 PRPF4	1	PRPF4 [nucleoplasm] (R-HSA-71890)	0.527	2
UniProt:Q9BUQ8 DDX23	1	DDX23 [nucleoplasm] (R-HSA-71879)	0.527	4
UniProt:O95400 CD2BP2	1	CD2BP2 [nucleoplasm] (R-HSA-72054)	0.527	2
UniProt:Q96DI7 SNRNP40	1	SNRNP40 [nucleoplasm] (R-HSA-71877)	0.527	2
UniProt:O75643 SNRNP200	1	SNRNP200 [nucleoplasm] (R-HSA-71885)	0.508	5
UniProt:Q9H0F7 ARL6	2	ARL6 [cilium] (R-HSA-5617766) ARL6 [plasma membrane] (R-HSA-5624078)	0.508	2
UniProt:P63165 SUMO1	11	lysyl-G97-SUMO1 [plasma membrane] (R-HSA-9762382) lysyl-G97-SUMO1 [nucleolus] (R-HSA-9762385) lysyl-G97-SUMO1 [viral capsid] (R-HSA-9762386) UBE2I-G97-SUMO1 [cytosol] (R-HSA-4656941) lysyl-G97-SUMO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9762380) lysyl-G97-SUMO1 [cytosol] (R-HSA-9762266) UBE2I-G97-SUMO1 [nucleoplasm] (R-HSA-3730622) UBA2-G97-SUMO1 [nucleoplasm] (R-HSA-3730616) SUMO1 [nucleoplasm] (R-HSA-877304) SUMO1(2-101) [nucleoplasm] (R-HSA-2990831) lysyl-G97-SUMO1 [nucleoplasm] (R-HSA-9761562)	0.499	2
UniProt:P55854 SUMO3	5	SUMO3(1-103) [nucleoplasm] (R-HSA-2990830) UBA2-G92-SUMO3 [nucleoplasm] (R-HSA-3730627) lysyl-G92-SUMOyl-K11-SUMO3 [nucleoplasm] (R-HSA-9761547) SUMO3 [nucleoplasm] (R-HSA-2984269) UBE2I-G92-SUMO3 [nucleoplasm] (R-HSA-3730611)	0.499	2
UniProt:P26368 U2AF2	2	5OHK15,276-U2AF2 [nucleoplasm] (R-HSA-9630011) U2AF2 [nucleoplasm] (R-HSA-71987)	0.483	2
UniProt:Q9NR30 DDX21	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.483	2
UniProt:Q15029 EFTUD2	1	EFTUD2 [nucleoplasm] (R-HSA-71883)	0.483	2

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