Reactome | SMU1 [nucleoplasm]

SMU1 [nucleoplasm]

Stable Identifier

R-HSA-9770259

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

WD40 repeat-containing protein SMU1, SMU1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q2TAY7 SMU1

Gene Names

SMU1

Chain

chain:1-513, initiator methionine:, chain:2-513

Reference Genes

BioGPS Gene:55234 SMU1

COSMIC (genes):SMU1 SMU1

CTD Gene:55234 SMU1

dbSNP Gene:55234 SMU1

ENSEMBL:ENSG00000122692 SMU1

ENSEMBL_homo_sapiens_GENE:ENSG00000122692.9 SMU1

HGNC:18247 SMU1

KEGG Gene (Homo sapiens):55234 SMU1

Monarch:55234 SMU1

NCBI Gene:55234 SMU1

OMIM:617811 SMU1

UCSC:Q2TAY7 SMU1

Reference Transcript

RefSeq:NM_018225.2 SMU1

Other Identifiers

11730283_at

11730284_x_at

11730285_at

11730286_a_at

17093172

218393_PM_s_at

218393_s_at

222618_PM_at

222618_at

233946_PM_at

233946_at

2438748

2438749

2438750

2438751

2438752

2438753

2438754

2438755

2438757

3203378

3203380

3203381

3203383

3203384

3203385

3203386

3203387

3203390

3203394

3203395

3203396

3203398

3203400

3203401

3203404

3203405

3203407

3203408

48272_at

48401_at

55234

68374_at

73082_at

8160622

A_23_P123874

GE62325

GO:0000381

GO:0000398

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0006397

GO:0008380

GO:0016071

GO:0016607

GO:0043226

GO:0071005

GO:0071011

HMNXSV003022793

Hs.193128.0.S2_3p_at

ILMN_1764803

PH_hs_0032681

TC09001007.hg

g8922678_3p_a_at

Participates

as an output of

Formation of the Spliceosomal Bact complex (Homo sapiens)

as a component of

as an input of

Formation of the Spliceosomal Pre-B complex (Homo sapiens)

Inferred To

smu-1 [nucleoplasm] (Caenorhabditis elegans)

smu1 [nucleoplasm] (Dictyostelium discoideum)

smu1 [nucleoplasm] (Xenopus tropicalis)

Ghost homologue of SMU1 [nucleoplasm] (Schizosaccharomyces pombe)

Smu1 [nucleoplasm] (Drosophila melanogaster)

Smu1 [nucleoplasm] (Mus musculus)

Smu1 [nucleoplasm] (Rattus norvegicus)

SMU1 [nucleoplasm] (Bos taurus)

SMU1 [nucleoplasm] (Canis familiaris)

SMU1 [nucleoplasm] (Gallus gallus)

SMU1 [nucleoplasm] (Plasmodium falciparum)

SMU1 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_060695.2

OpenTargets

ENSG00000122692

GeneCards

Q2TAY7

HPA

ENSG00000122692-SMU1

Ensembl

ENST00000397149, ENSP00000380336, ENSG00000122692

PRO

Q2TAY7

Pharos - Targets

Q2TAY7

PDB

5O9Z, 6Q8J, 6Q8F, 8QO9, 6Q8I, 6AHD

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13123 IK	1	IK [nucleoplasm] (R-HSA-9770239)	0.872	8
UniProt:Q96HT8 MR1L1			0.831	9
UniProt:Q9Y605 MOFA1			0.556	5
UniProt:Q4VC12 MSS51			0.556	3
UniProt:A6NK89 RASFA			0.556	3
UniProt:O43711 TLX3			0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q9Y5P4-2 CERT1	5	p-S132-CERT1-2 [cytosol] (R-HSA-429704) p-S,S132,T-CERT1-2 [cytosol] (R-HSA-429695) p-S,S132,T-CERT1-2 [endoplasmic reticulum membrane] (R-HSA-429727) CERT1-2 [endoplasmic reticulum membrane] (R-HSA-429665) CERT1-2 [cytosol] (R-HSA-429712)	0.556	3
UniProt:P49821 NDUFV1	1	NDUFV1 [mitochondrial inner membrane] (R-HSA-163926)	0.556	3
UniProt:O94906 PRPF6	1	PRPF6 [nucleoplasm] (R-HSA-71881)	0.508	2
UniProt:O95400 CD2BP2	1	CD2BP2 [nucleoplasm] (R-HSA-72054)	0.502	2

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