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DDX23 [nucleoplasm]
Stable Identifier
R-HSA-71879
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
U5-100 kDa protein
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U4:U5:U6 tri-snRNP complex [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U4:U5:U6 tri-snRNP complex [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
U4:U5:U6 tri-snRNP complex [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
mRNA Splicing - Minor Pathway (Homo sapiens)
ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Homo sapiens)
ATAC C Complex with lariat containing 5'-end cleaved mRNA [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Homo sapiens)
ATAC C Complex [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
ATAC C Complex with lariat containing 5'-end cleaved mRNA [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
Formation of AT-AC B Complex (Homo sapiens)
ATAC B Complex [nucleoplasm] (Homo sapiens)
U4 ATAC:U5:U6 ATAC Complex [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
U4 ATAC:U5:U6 ATAC Complex [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
Formation of AT-AC C complex (Homo sapiens)
ATAC B Complex [nucleoplasm] (Homo sapiens)
U4 ATAC:U5:U6 ATAC Complex [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
ATAC C Complex [nucleoplasm] (Homo sapiens)
U5 snRNP [nucleoplasm] (Homo sapiens)
DDX23 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BUQ8 DDX23
Gene Names
DDX23
Chain
chain:1-820
Reference Genes
BioGPS Gene:9416 DDX23
COSMIC (genes):DDX23 DDX23
CTD Gene:9416 DDX23
dbSNP Gene:9416 DDX23
ENSEMBL:ENSG00000174243 DDX23
ENSEMBL_homo_sapiens_GENE:ENSG00000174243.11 DDX23
HGNC:17347 DDX23
KEGG Gene (Homo sapiens):9416 DDX23
Monarch:9416 DDX23
NCBI Gene:9416 DDX23
OMIM:612172 DDX23
UCSC:Q9BUQ8 DDX23
Reference Transcript
RefSeq:NM_004818.2 DDX23
Other Identifiers
11715902_a_at
11752973_a_at
16764019
201440_PM_at
201440_at
3415503
3415509
3415511
3415513
3415516
3415518
3453320
3453321
3453322
3453323
3453325
3453326
3453327
3453328
3453329
3453332
3453333
3453334
3453335
3453337
3453339
3453340
3453341
3453342
3453343
3453344
3453346
3453347
40465_PM_at
40465_at
71551_at
7962869
9416
A_23_P64770
GE81444
GO:0000166
GO:0000354
GO:0000375
GO:0000398
GO:0000785
GO:0003676
GO:0003723
GO:0003724
GO:0003824
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005681
GO:0005682
GO:0005694
GO:0005730
GO:0006325
GO:0006397
GO:0008380
GO:0016071
GO:0016787
GO:0016887
GO:0043226
GO:0046540
GO:0062176
GO:0065003
GO:0070062
GO:0071013
GO:0140098
GO:0140657
HMNXSV003016158
HMNXSV003032744
ILMN_1784218
PH_hs_0022434
TC12001458.hg
g4759277_3p_s_at
Participates
as an output of
Formation of the Spliceosomal B complex (Homo sapiens)
as a component of
U5 snRNP [nucleoplasm] (Homo sapiens)
Inferred To
DDX23 [nucleoplasm]
(Bos taurus)
DDX23 [nucleoplasm]
(Canis familiaris)
DDX23 [nucleoplasm]
(Dictyostelium discoideum)
DDX23 [nucleoplasm]
(Gallus gallus)
DDX23 [nucleoplasm]
(Schizosaccharomyces pombe)
ddx-23 [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of DDX23 [nucleoplasm]
(Plasmodium falciparum)
Ghost homologue of DDX23 [nucleoplasm]
(Sus scrofa)
Ddx23 [nucleoplasm]
(Mus musculus)
Ddx23 [nucleoplasm]
(Rattus norvegicus)
Dmel\CG10333 [nucleoplasm]
(Drosophila melanogaster)
ddx23 [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_004809.2
OpenTargets
ENSG00000174243
IntEnz
3.6.4.13
GeneCards
Q9BUQ8
HPA
ENSG00000174243-DDX23
Ensembl
ENSP00000446770
,
ENSG00000174243
,
ENST00000547135
,
ENSP00000310723
,
ENST00000308025
PRO
Q9BUQ8
Pharos - Targets
Q9BUQ8
HMDB Protein
HMDBP11666
PDB
4NHO
,
3JCR
,
6QW6
,
6QX9
,
6AH0
Interactors (27)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96DI7 SNRNP40
1
SNRNP40 [nucleoplasm]
(R-HSA-71877)
0.744
5
UniProt:O95400 CD2BP2
1
CD2BP2 [nucleoplasm]
(R-HSA-72054)
0.744
5
UniProt:O43172 PRPF4
1
PRPF4 [nucleoplasm]
(R-HSA-71890)
0.669
3
UniProt:Q15029 EFTUD2
1
EFTUD2 [nucleoplasm]
(R-HSA-71883)
0.643
4
UniProt:P62316 SNRPD2
2
SNRPD2 [nucleoplasm]
(R-HSA-71901)
SNRPD2 [cytosol]
(R-HSA-191810)
0.643
3
UniProt:Q6P2Q9 PRPF8
1
PRPF8 [nucleoplasm]
(R-HSA-83810)
0.643
4
UniProt:P62306 SNRPF
2
SNRPF [nucleoplasm]
(R-HSA-71907)
SNRPF [cytosol]
(R-HSA-191852)
0.643
4
UniProt:Q15428 SF3A2
1
SF3A2 [nucleoplasm]
(R-HSA-71964)
0.564
2
UniProt:P62304 SNRPE
2
SNRPE [nucleoplasm]
(R-HSA-71905)
SNRPE [cytosol]
(R-HSA-191782)
0.527
4
UniProt:Q9UBB9 TFIP11
1
TFIP11 [nucleoplasm]
(R-HSA-8869310)
0.527
2
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.527
2
UniProt:O43395 PRPF3
1
PRPF3 [nucleoplasm]
(R-HSA-6806806)
0.527
3
UniProt:P11387 TOP1
2
monoSUMO1-K117-TOP1 [nucleoplasm]
(R-HSA-4641364)
TOP1 [nucleoplasm]
(R-HSA-4641363)
0.527
2
UniProt:P14678 SNRPB
4
SNRPB [nucleoplasm]
(R-HSA-71896)
Me2-R108,R112-SNRPB [nucleoplasm]
(R-HSA-192213)
SNRPB [cytosol]
(R-HSA-191798)
2xMe-SNRPB [cytosol]
(R-HSA-192218)
0.527
3
UniProt:O43290 SART1
1
SART1 [nucleoplasm]
(R-HSA-4615999)
0.527
4
UniProt:P83876 TXNL4A
1
TXNL4A [nucleoplasm]
(R-HSA-71875)
0.527
3
UniProt:Q9Y5B6 PAXB1
0.527
2
UniProt:O75643 SNRNP200
1
SNRNP200 [nucleoplasm]
(R-HSA-71885)
0.527
3
UniProt:P63162 SNRPN
1
Me2-R108,R112-SNRPN [nucleoplasm]
(R-HSA-8865931)
0.527
3
UniProt:P16383 GCFC2
1
GCFC2 [nucleoplasm]
(R-HSA-8869311)
0.527
2
UniProt:Q13523 PRPF4B
1
PRPF4B [nucleoplasm]
(R-HSA-9769525)
0.527
2
UniProt:Q9Y312 AAR2
0.527
4
UniProt:O94906 PRPF6
1
PRPF6 [nucleoplasm]
(R-HSA-71881)
0.527
3
UniProt:Q13123 IK
1
IK [nucleoplasm]
(R-HSA-9770239)
0.527
2
UniProt:Q96LA8 PRMT6
1
PRMT6 [nucleoplasm]
(R-HSA-5226884)
0.527
2
UniProt:Q56P03 EAPP
0.527
2
UniProt:P54274 TERF1
1
TERF1 [nucleoplasm]
(R-HSA-164618)
0.508
2
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